Автор: Pimentel, Enrique Название: Revival: Handbook of Growth Factors (1994) ISBN: 1138559512 ISBN-13(EAN): 9781138559516 Издательство: Taylor&Francis Рейтинг: Цена: 9492.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Volume I of this book provides a comprehensive discussion of the factors involved in regulation of the cell cycle, the general biological properties of growth factors, and the receptor and postreceptor mechanisms of action of these signaling agents.
Автор: Timothy R. Hughes Название: A Handbook of Transcription Factors ISBN: 9400736045 ISBN-13(EAN): 9789400736047 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Written from a genome-based perspective, this volume provides an objective overview of transcription factor biochemistry. Topics include known transcription factor classes, origins and evolution of transcription factor types, and mechanisms of interaction with chromatin.
The fibroblast growth factor (FGF) family of ligands and the corresponding family of FGF receptor tyrosine kinases comprise one of the most versatile and diverse growth factor signaling families in vertebrates, found virtually in every tissue and cell type where they regulate metabolic and physiologic function, maintain tissue homeostasis, and mediate injury response, tissue repair, and regeneration. As a result, FGFs play critical roles in a wide variety of normal biological and abnormalities in FGF signaling can lead to a variety of disease states from developmental malformations, to atherosclerosis, pulmonary hypertension and cancer among many others. A thorough understanding of this system is necessary for critical insights into both normal and disease biology and is essential to development of rationale therapeutic strategies aimed at treatment of FGF-dependent diseases states.
Recent years have seen advances in our understanding of FGFs role in endothelial and, more general, vascular biology, the subject of this book. In particular, FGFs have been implicated in the maintenance of vascular homeostasis and control of blood vessel permeability while aberrant FGF signaling has been shown to be central to the development of pulmonary hypertension, and endothelial-to-mesenchymal transition, a process implicated in the development of atherosclerosis. Finally, FGFs ability to stimulate blood vessel growth has been explored in therapeutic angiogenesis approaches.
With this in mind, the present monograph is structured to provide comprehensive information to a reader interested in FGFs in general and vascular biology in particular. To this end, we explore everything from the structure and signaling of FGFs and their receptors (Chapters 1, 2 and 3) to their role in the regulation of vascular homeostasis (Chapter 4) and cardiovascular diseases (Chapters 5 and 6). We then address new developments in FGF therapeutics (chapter 7) and explore FGF biology in the epithelium (Chapter 8) thereby providing a complete analysis of this growth factor family biology in two closely related but distinctly different environments -- endothelium and epithelium. Finally, we examine FGF biology in eye disease and in cancer.
It is our hope that this comprehensive treatment of FGF vascular biology and its application will provide the reader with the accurate and timely summary of this rapidly moving field.
Автор: John R. Wingard; George D. Demetri Название: Clinical Applications of Cytokines and Growth Factors ISBN: 0792384865 ISBN-13(EAN): 9780792384861 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Reviews the biological interactions between hematopoietic progenitors, growth factors and cytokines, and the stromal micro-environment that have provided the scientific basis for our understanding of hematopoiesis. This book presents the pathophysiology of neutropenia, anemia and thrombocytopenia.
Автор: Lena Claesson-Welsh Название: Vascular Growth Factors and Angiogenesis ISBN: 3642641954 ISBN-13(EAN): 9783642641954 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Argues that cell signalling via nerves, hormones, local mediators and growth factors are not distinct phenomena, but branches of one general mechanism. This volume is designed to act as a bridge between general texts and is aimed at biologists coming to the topic from a variety of backgrounds.
Автор: David W. Schomberg Название: Growth Factors in Reproduction ISBN: 1461278198 ISBN-13(EAN): 9781461278191 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Symposium on Growth Factors in Reproduction, sponsored by Serono Symposia, USA, held April 1 to 4, 1990, in Savannah, Georgia
Автор: Piero P. Foa Название: Humoral Factors in the Regulation of Tissue Growth ISBN: 1461392748 ISBN-13(EAN): 9781461392743 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Experts in the field of endocrinology as well as ophthalmologists, oncologists, orthopedists and oral surgeons discuss the nature and mechanism of action of growth-stimulating substances whose biological and clinical activities in humans have been demonstrated or are being investigated.
Автор: Mark Bothwell Название: Neuronal Growth Factors ISBN: 3642757499 ISBN-13(EAN): 9783642757495 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Nerve growth factor (NGF) was the first such factor to be characterized (LEVI- MONTALCINI and HAMBURGER 1953) and has served as the model against which all similar factors are compared. These include: three structurally related factors, NGF itself (SCOTT et al. acidic and basic fibroblast growth factors (aFGF, bFGF) (ABRAHAM et al.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
