Cafer's Antipsychotics is an essential resource for any prescriber of psychiatric medication. Filled with pictures, this book makes complex concepts easy to understand and provides tools for remembering more than you thought possible.
To help you match trade names with generic names of 40 medications, this book features mascots akin to the Xyzal "Wise Owl" and Myrbetriq Bladder characters.
Each medication's mascot is incorporated into a visual-mnemonic framework designed for recollection of pharmacokinetic interactions. For instance, CYP2C19 substrates are represented as flowers with CYP2C19 inhibitors as watering cans to make the flowers grow. CYP1A2 substrates are trees to be chopped down by axes (CYP1A2 inducers).
In addition to antipsychotics, this book features medications used for treatment of antipsychotic-induced side effects, including dopamine-depleting agents and anticholinergics.
Название: Methods for Studying Nucleic Acid/Drug Interactions ISBN: 1138382035 ISBN-13(EAN): 9781138382039 Издательство: Taylor&Francis Рейтинг: Цена: 9492.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Since most therapeutic efforts have been predominantly focused on pharmaceuticals that target proteins, there is an unmet need to develop drugs that intercept cellular pathways that critically involve nucleic acids. Progress in the discovery of nucleic acid binding drugs naturally relies on the availability of analytical methods that assess the efficacy and nature of interactions between nucleic acids and their putative ligands. This progress can benefit tremendously from new methods that probe nucleic acid/ligand interactions both rapidly and quantitatively.
A variety of novel methods for these studies have emerged in recent years, and Methods for Studying DNA/Drug Interactions highlights new and non-conventional methods for exploring nucleic acid/ligand interactions. Designed to present drug-developing companies with a survey of possible future techniques, the book compares their drawbacks and advantages with respect to commonly used tools. Perhaps more importantly, this book was written to inspire young scientists to continue to advance these methods into fruition, especially in light of current capabilities for assay miniaturization and enhanced sensitivity using microfluidics and nanomaterials.
Название: Drug-Drug Interactions ISBN: 036745274X ISBN-13(EAN): 9780367452742 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Authored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical, clinical, toxicological, and regulatory perspectives.
Thoroughly updated, this second edition reflects the significant advances and includes extensive new material on:
key interplay between transporters and enzymes in drug metabolism and drug interactions
the integral role of pharmacogenetics in metabolism-based drug-drug interactions
in vivo - in vitro correlations (reversible, mechanism-based inhibition, induction)
in silico approaches enabling structure-activity and structure-function studies
high-throughput screening and GLP methods for evaluating drug interactions in vitro
the use of transgenic animal models to evaluate drug interactions
Providing helpful case examples and computer-aided modeling, Drug-Drug Interactions is filled with over 200 invaluable tables, equations, and figures to clarify key concepts, and incorporates critical new updated information.
Описание: The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Antimicrobial Drug Interactions,” delivers a quick clinical resource that distills relevant drug interactions by antimicrobial drug class. The book provides informative tables on specific drug-drug interactions that include the degree and severity of the expected interaction. A mechanistic basis for drug-drug interactions is also provided to link observed interactions to pharmacologic characteristics of key drug classes. This complete resource is organized by major antibacterial, antimycobacterial, antiviral, antifungal, antimalarial, and antiprotozoal class. In line with current innovations in antimicrobial drug development, a distinct chapter on the pharmacologic management of drug interactions in hepatitis B virus (HBV) and hepatitis C virus (HCV)-related infections is included. Two new chapters are dedicated to the management of human immunodeficiency virus (HIV) drug-drug interactions given the breadth of antiretroviral class-specific effects. This comprehensive review of known drug interactions and strategies to manage them is an invaluable resource to all health care practitioners.
Автор: K. Baxter (ed.) Название: Stockley`s Drug Interactions - Book & CD-ROM Package ISBN: 085369916X ISBN-13(EAN): 9780853699163 Издательство: Pharmaceutical Press Рейтинг: Цена: 46530.00 р. Наличие на складе: Поставка под заказ.
Описание: The most indispensable and authoritative international source of drug interaction information.
Автор: Karen Baxter (ed.) Название: Stockley`s Drug Interactions Pocket Companion ISBN: 0853699178 ISBN-13(EAN): 9780853699170 Издательство: Pharmaceutical Press Цена: 4552.00 р. Наличие на складе: Поставка под заказ.
Описание: A-Z of drugs listed in Stockley’s Drug Interactions
Описание: This comprehensive review provides a systematic, unbiased analysis, critique and summary of the available literature and generates novel clinical decision-making algorithms which can aid clinicians and scientists in practice management and research development. Potential mechanisms for the identified drug interactions are deduced from available preclinical and in vitro data which are interpreted in the context of the in vivo findings. Current limitations and gaps in the literature are summarized, and potential future research directions / experimentations are also suggested. In addition to the main objective to review the available clinical pharmacokinetic and pharmacodynamic drug interactions associated with WHO-recommended antimalarial drugs on the market today (i.e. chloroquine, amodiaquine, sulfadoxine, pyrimethamine, mefloquine, artemisinin, artemether, artesunate, dihydroartemisinin, artemotil, lumefantrine, primaquine, atovaquone, proguanil, piperaquine and quinine), this book also provides succinct chapter summaries on the epidemiology of malaria infection, diagnosis and therapeutics, in vivo pharmacology and chemistry, preclinical pharmacology, in vitro pharmacodynamics, in vitro reaction phenotyping, and in vitro drug-drug interaction data associated with the identified antimalarial drugs.
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