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Methods for Studying Nucleic Acid/Drug Interactions, 


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Цена: 9492.00р.
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Название:  Methods for Studying Nucleic Acid/Drug Interactions
ISBN: 9781138382039
Издательство: Taylor&Francis
Классификация:


ISBN-10: 1138382035
Обложка/Формат: Paperback
Страницы: 408
Вес: 0.75 кг.
Дата издания: 30.08.2019
Язык: English
Иллюстрации: 19 tables, black and white; 154 illustrations, black and white
Размер: 234 x 156
Читательская аудитория: Tertiary education (us: college)
Основная тема: Biotechnology
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

Since most therapeutic efforts have been predominantly focused on pharmaceuticals that target proteins, there is an unmet need to develop drugs that intercept cellular pathways that critically involve nucleic acids. Progress in the discovery of nucleic acid binding drugs naturally relies on the availability of analytical methods that assess the efficacy and nature of interactions between nucleic acids and their putative ligands. This progress can benefit tremendously from new methods that probe nucleic acid/ligand interactions both rapidly and quantitatively.

A variety of novel methods for these studies have emerged in recent years, and Methods for Studying DNA/Drug Interactions highlights new and non-conventional methods for exploring nucleic acid/ligand interactions. Designed to present drug-developing companies with a survey of possible future techniques, the book compares their drawbacks and advantages with respect to commonly used tools. Perhaps more importantly, this book was written to inspire young scientists to continue to advance these methods into fruition, especially in light of current capabilities for assay miniaturization and enhanced sensitivity using microfluidics and nanomaterials.




Protein-Ligand Interactions: Methods and Applications

Автор: Daviter Tina, Johnson Christopher M., McLaughlin Stephen H.
Название: Protein-Ligand Interactions: Methods and Applications
ISBN: 1071611992 ISBN-13(EAN): 9781071611999
Издательство: Springer
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Цена: 18167.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This third edition provides new and updated chapters detailing a complete introduction to common and emerging procedures for characterizing the interactions of individual proteins with their natural ligands, drugs or other binding partners.

Mechanisms of Drug Interactions

Автор: Patrick F. D`Arcy; James C. McElnay; Peter G. Well
Название: Mechanisms of Drug Interactions
ISBN: 3642646581 ISBN-13(EAN): 9783642646584
Издательство: Springer
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Цена: 18284.00 р.
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Описание: With contributions by numerous experts

Electron Spin Interactions in Chemistry and Biology: Fundamentals, Methods, Reactions Mechanisms, Magnetic Phenomena, Structure Investigation

Автор: Likhtenshtein Gertz
Название: Electron Spin Interactions in Chemistry and Biology: Fundamentals, Methods, Reactions Mechanisms, Magnetic Phenomena, Structure Investigation
ISBN: 3319816349 ISBN-13(EAN): 9783319816340
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This book presents the versatile and pivotal role of electron spin interactions in nature. It provides the background, methodologies and tools for basic areas related to spin interactions, such as spin chemistry and biology, electron transfer, light energy conversion, photochemistry, radical reactions, magneto-chemistry and magneto-biology.

Protein-Ligand Interactions: Methods and Applications

Автор: Daviter Tina, Johnson Christopher M., McLaughlin Stephen H.
Название: Protein-Ligand Interactions: Methods and Applications
ISBN: 1071611968 ISBN-13(EAN): 9781071611968
Издательство: Springer
Цена: 18167.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This third edition provides new and updated chapters detailing a complete introduction to common and emerging procedures for characterizing the interactions of individual proteins with their natural ligands, drugs or other binding partners.

Nanotechnology for Nucleic Acid Delivery: Methods and Protocols

Автор: Ogris Manfred, Oupicky David
Название: Nanotechnology for Nucleic Acid Delivery: Methods and Protocols
ISBN: 1493959328 ISBN-13(EAN): 9781493959327
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This Methods in Molecular Biology (TM) series book covers nanoparticulate delivery of nucleic acids in terms of biosafety, particle synthesis as well as its application in cell culture. Includes materials and reagents, protocols, notes on troubleshooting and more.

Molecular Beacons: Signalling Nucleic Acid Probes, Methods, and Protocols

Автор: Marx
Название: Molecular Beacons: Signalling Nucleic Acid Probes, Methods, and Protocols
ISBN: 1617377260 ISBN-13(EAN): 9781617377266
Издательство: Springer
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Цена: 18167.00 р.
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Описание: From probe design to applications in clinical settings, this book provides a diverse set of instructive examples, guided by experts in the field who offer easy-to-follow experimentals.

Diet and Drug Interactions

Автор: Daphne A. Roe
Название: Diet and Drug Interactions
ISBN: 940116049X ISBN-13(EAN): 9789401160490
Издательство: Springer
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Цена: 13060.00 р.
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Описание: When we learn from a patient, clinician, or medical record that a drug has been discontinued, it is logical to ask why. Drugs may also produce nutritional deficiencies, especially in a patient whose diet is marginal in those nutrients depleted by the particular drug.

Enzyme- and Transporter-Based Drug-Drug Interactions

Автор: K. Sandy Pang; A. David Rodrigues; Raimund M. Pete
Название: Enzyme- and Transporter-Based Drug-Drug Interactions
ISBN: 1441908390 ISBN-13(EAN): 9781441908391
Издательство: Springer
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Цена: 32652.00 р.
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Описание: This proceedings volume from the annual meeting of The American Association of Pharmaceutical Scientists, held November 2007, examines enzyme- and transporter-based DDIs that impact the absorption and disposition of drugs and impact on adverse outcomes.

Affinity And Efficacy: The Components Of Drug-Receptor Interactions

Автор: Ehlert Frederick J
Название: Affinity And Efficacy: The Components Of Drug-Receptor Interactions
ISBN: 9814322563 ISBN-13(EAN): 9789814322560
Издательство: World Scientific Publishing
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Цена: 38016.00 р.
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Описание: The interaction of a drug with a receptor encodes a vector of information having components of affinity and efficacy. This book describes how to analyze various responses to estimate the affinity and efficacy components of the initial drug-receptor interaction.

Enzyme- and Transporter-Based Drug-Drug Interactions

Автор: K. Sandy Pang; A. David Rodrigues; Raimund M. Pete
Название: Enzyme- and Transporter-Based Drug-Drug Interactions
ISBN: 1489994890 ISBN-13(EAN): 9781489994899
Издательство: Springer
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Цена: 28732.00 р.
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Описание: This proceedings volume from the annual meeting of The American Association of Pharmaceutical Scientists, held November 2007, examines enzyme- and transporter-based DDIs that impact the absorption and disposition of drugs and impact on adverse outcomes.

Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials

Автор: Tony K.L. Kiang; Kyle John Wilby; Mary H.H. Ensom
Название: Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials
ISBN: 3319381938 ISBN-13(EAN): 9783319381930
Издательство: Springer
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Цена: 8384.00 р.
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Описание: Introduction.- Pharmacology of Recommended Antimalarial Agents.- Drug Interaction Potential of Antimalarial Drugs Based on Known Metabolic Properties of Antimalarials.- Pharmacokinetic Drug Interactions Affecting Antimalarials.- Effects of Antimalarials on the Pharmacokinetics of Co-Administered Drugs.- Effects of Antimalarials on the Pharmacokinetics of Co-Administered Antimalarials.- Pharmacodynamic Interactions: Clinical Evidence for Combination Therapy, In Vitro Interactions, and In Vivo Interactions.- Limitations, Future Directions, and Conclusions.

Handbook of Drug Interactions

Автор: Ashraf Mozayani; Lionel Raymon
Название: Handbook of Drug Interactions
ISBN: 1493958232 ISBN-13(EAN): 9781493958238
Издательство: Springer
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Цена: 30606.00 р.
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Описание: Adverse drug reactions and interactions are still a major headache for healthcare professionals around the world. The US Food and Drug Administration's database recorded almost 300,000 serious adverse events in 2009 alone, of which 45,000 instances proved fatal. This updated new edition of the indispensable guide to drug interactions incorporates fresh research completed since the book's original publication by Humana Press in 2004. Additions include a new section on pharmacogenomics, a rapidly growing field that explores the genetic basis for the variability of responses to drugs. This new material reviews important polymorphisms in drug metabolizing enzymes and applies the findings to forensic interpretation, using case studies involving opiates as exemplars. Existing chapters from the first edition have in most cases been updated and reworked to reflect new data or incorporate better tables and diagrams, as well as to include recent drugs and formulations. Recent references have been inserted too. The handbook features extra material on illicit drug use, with a new chapter tackling the subject that covers cocaine, amphetamines and cannabis, among others. The section on the central nervous system also deals with a number of drugs that are abused illicitly, such as benzodiazepines, opiates flunitrazepam and GHB, while so-called 'social' drugs such as alcohol and nicotine are still discussed in the book's section on environmental and social pharmacology. Focusing as before on detailed explanation and incorporating both pharmacokinetic and pharmacodynamic drug interactions, this book will continue to be a lodestar for health and forensic professionals as well as students.


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