What was life like on our planet long before the early humans emerged?
Paleontologist Dr. Mark P. Witton draws on the latest twenty-first century discoveries to re-create the appearances and lifestyles of extinct, fascinating species, the environments they inhabited, and the challenges they faced living on an ever-changing planet. A worthy successor to Charles Knight's beloved 1946 classic, Life through the Ages II takes us on an unforgettable journey through the evolution of life on Earth.
Dozens of gorgeous color illustrations and meticulously researched, accompanying commentary showcase the succession of lost worlds, defining events, and ancient creatures that have appeared since the earth was formed, creating an indispensable guide to explore what came before us.
Автор: Humphries Mark Название: The Spike: An Epic Journey Through the Brain in 2.1 Seconds ISBN: 0691195889 ISBN-13(EAN): 9780691195889 Издательство: Wiley Рейтинг: Цена: 3168.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
The story of a neural impulse and what it reveals about how our brains work
We see the last cookie in the box and think, can I take that? We reach a hand out. In the 2.1 seconds that this impulse travels through our brain, billions of neurons communicate with one another, sending blips of voltage through our sensory and motor regions. Neuroscientists call these blips "spikes." Spikes enable us to do everything: talk, eat, run, see, plan, and decide. In The Spike, Mark Humphries takes readers on the epic journey of a spike through a single, brief reaction. In vivid language, Humphries tells the story of what happens in our brain, what we know about spikes, and what we still have left to understand about them. Drawing on decades of research in neuroscience, Humphries explores how spikes are born, how they are transmitted, and how they lead us to action. He dives into previously unanswered mysteries: Why are most neurons silent? What causes neurons to fire spikes spontaneously, without input from other neurons or the outside world? Why do most spikes fail to reach any destination? Humphries presents a new vision of the brain, one where fundamental computations are carried out by spontaneous spikes that predict what will happen in the world, helping us to perceive, decide, and react quickly enough for our survival. Traversing neuroscience's expansive terrain, The Spike follows a single electrical response to illuminate how our extraordinary brains work.
Автор: Strachan Название: Human Molecular Genetics ISBN: 0815345895 ISBN-13(EAN): 9780815345893 Издательство: Taylor&Francis Рейтинг: Цена: 12095.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology.
Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation.
Key features:
Fully integrated approach to the molecular aspects of human genetics, genomics, and cell biology
Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms
Summary boxes at the end of each chapter provide clear learning points
Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study
Reorganized into five sections for improved access to related topics
Also new to this edition - brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics
A proven and popular textbook for upper-level undergraduates and graduate students, the new edition of Human Molecular Genetics remains the 'go-to' book for those studying human molecular genetics or genomics courses around the world.
Автор: Tina M. Henkin, Joseph E. Peters Название: Snyder and Champness Molecular Genetics of Bacteria ISBN: 1555819753 ISBN-13(EAN): 9781555819750 Издательство: Wiley Рейтинг: Цена: 18208.00 р. Наличие на складе: Поставка под заказ.
Описание: Revised edition of: Molecular genetics of bacteria / Larry Snyder ... [et al.]. 4th ed. c2013.
Автор: Tseng Charles C Название: Learning Genetics Through Chromosome Modeling ISBN: 1461460824 ISBN-13(EAN): 9781461460824 Издательство: Springer Рейтинг: Цена: 10480.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Designed to help teach genetics with greater ease and less anxiety, this book includes a comprehensive, interactive learning program developed at at the University of Chicago and Purdue University, that focuses on chromosome simulation and model building.
For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions.
Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have engendered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field.
Название: Applying Pharmacogenomics in Therapeutics ISBN: 1466582677 ISBN-13(EAN): 9781466582675 Издательство: Taylor&Francis Рейтинг: Цена: 27562.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Recent advances in high-throughput gene sequencing and other omics biotechnologies have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is now generally accepted as the major determinant of variable drug safety, efficacy, and cost-effectiveness. Therefore, widespread use of pharmacogenomics for patient care has become a critical requirement. There is an unprecedented urgency for aspiring and practicing clinicians to become trained on how to interpret data from pharmacogenomic testing in preparation for the future of healthcare--i.e., personalized medicine.
Applying Pharmacogenomics in Therapeutics provides timely coverage of the principles, practice, and potential of pharmacogenomics and personalized medicine. Comprised of chapters contributed by well-established pharmacologists and scientists from US and Chinese academia and industry, this authoritative text:
Demonstrates how to apply the principles of pharmacogenomics and its biotechnologies in patient care
Depicts the use of genetic biomarkers in drug discovery and development, laboratory medicine, and clinical services
Describes the practice of pharmacogenomics in the treatment of cancers, cardiovascular diseases, neurologic and psychiatric disorders, and pulmonary diseases
Discusses the merging of pharmacogenomics and alternative medicine, as well as the integration of pharmacogenomics into pharmacoeconomics
Each chapter begins with the key concepts, followed by in-depth explorations of case reports or critical evaluations of genetic variants/biomarkers, and concludes with questions for self-examination.
Автор: Karobi Moitra Название: A Journey Through Genetics, Part 2 ISBN: 1615046623 ISBN-13(EAN): 9781615046621 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 9286.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Explores the exciting discoveries in genetics and molecular biology. This volume takes the reader on a journey to explore the frontiers of genetic diversity, gene cloning, the human journey, and the human genome project. The book is targeted at undergraduate non-majors and also as a "companion" to a standard genetics textbook for biology majors.
Автор: William S. Klug Название: Concepts of genetics, global edition 12 ed ISBN: 1292265329 ISBN-13(EAN): 9781292265322 Издательство: Pearson Education Рейтинг: Цена: 17224.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For all introductory genetics courses. Concepts of Genetics emphasises the fundamental ideas of genetics, while exploring modern techniques and applications of genetic analysis. This best-selling text continues to provide understandable explanations of complex, analytical topics and recognises the importance of teaching students how to become effective problem solvers.
The 12th Edition has been extensively updated to provide comprehensive coverage of important, emerging topics such as CRISPR-Cas and the study of posttranscriptional gene regulation in eukaryotes. An expanded emphasis on ethical considerations that genetics is bringing into everyday life is addressed in Genetics, Ethics, and Society and Case Study features.
Описание: Provides an overview of the progress made in molecular medicine applying genetics and genomics to the understanding, diagnosis, and treatment of human diseases. Specifically, the methods for identifying genes involved in human diseases are described. Examples from 10 genes and diseases are provided, drawing on the author`s research.
Описание: Lecture provides an overview of the progress made in molecular medicine applying genetics and genomics to the understanding, diagnosis, and treatment of human diseases. Specifically, the methods for identifying genes involved in human diseases are described. Examples from 10 genes and diseases will be provided, drawing on the author's research. Topics include examples from simple Mendelian diseases, such as cystic fibrosis, inherited cancers, oncogenes activated by chromosomal translocations, host genes involved in infectious disease, genes identified via genomewide association studies, pathogens causing cancer, and gene families contributing to multiple diseases. For each example, historical details will be provided as background for readers to understand the context and process of the discoveries, technologies explained, and current understanding and treatment implications detailed.
Описание: This book gives a basic and broad but innovative view of autism. It seeks to rupture stereotypes and stigmas and starts with the story and paintings of the artist Camila Falchi, who has an Autism Spectrum Disorder (ASD). Camila's art is evidence of the complexity of her internal world and its variety of themes, intensity of feelings, daydreaming, fantasy, and dreams. This complexity compels us to question and rethink our perceptions of the autism spectrum, the mind, and creativity. As a neurologist and a neuroscientist, our goal with this book is to disseminate knowledge about autism, its characteristics, and potentials by means of the example of this artist.
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