Название: Dna replication-repair interface ISBN: 0323907334 ISBN-13(EAN): 9780323907330 Издательство: Elsevier Science Рейтинг: Цена: 23244.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Replication-Coupled Repair, Volume 661 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including the Repair of replication-born DNA breaks by sister chromatid recombination, High resolution and high throughput DNA cyclization measurements to interrogate DNA bendability, A programmable detection method for genomic signatures: from disease diagnosis to genome editing, Characterization of the telomerase modulating activities of yeast DNA helicases, Eukaryotic DNA replication with purified budding yeast proteins, Single molecule studies of yeast Rad51 paralogs, Light activation and deactivation of Cas9 for DNA repair studies, and more.
Other chapters explore MIDAS: Direct sequencing to map mitotic DNA synthesis and common fragile sites at high precision, Studying the DNA damage response in embryonic systems, GLASS-ChIP to map Mre11 cleavage sites in the human genome, New chemical biology approaches to trap reaction intermediates in living cells, Single-molecule imaging approaches for monitoring replication fork conflicts at genomic DNA G4 structures and R-loops in human cells, Monitoring the replication of structured DNA through heritable epigenetic change, Visualizing replication fork encounters with DNA interstrand crosslinks, and much more.
Автор: Lee Tom Название: DNA Replication ISBN: 163239152X ISBN-13(EAN): 9781632391520 Издательство: Random House (USA) Цена: 11035.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: DNA replication is a basic part of the life cycle of all the organisms. Many characteristics of this process show thorough conservation across organisms in all domains of life. This book outlines and reviews the present condition of knowledge on numerous crucial aspects of the DNA replication procedure. DNA replication is a crucial process in both development and growth and in relation to a wide variety of pathological conditions including cancer. The book contains novel insights into the whole process of DNA replication covered under two broad sections, "Machines that Drive DNA Replication" and "Mechanisms that Protect Chromosome Integrity during DNA Replication". It is also a compilation of thought provoking questions and summaries to give way to future investigations.
Автор: Yang, Wei Название: DNA Repair and Replication ISBN: 0120342693 ISBN-13(EAN): 9780120342693 Издательство: Elsevier Science Рейтинг: Цена: 19370.00 р. Наличие на складе: Поставка под заказ.
Автор: Laura Kaguni Название: DNA Replication Across Taxa,39 ISBN: 0128047356 ISBN-13(EAN): 9780128047354 Издательство: Elsevier Science Рейтинг: Цена: 18528.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
DNA Replication Across Taxa, the latest volume in The Enzymes series summarizes the most important discoveries associated with DNA replication.
Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair, Volume 601, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field.
Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The molecular machines of recombination preserve the integrity of the genetic material in all organisms and generate genetic diversity in evolution. The same molecular machines that support genetic integrity by orchestrating accurate repair of the most deleterious DNA lesions, however, also promote survival of cancerous cells and emergence of radiation and chemotherapy resistance. This two-volume set offers a comprehensive set of cutting edge methods to study various aspects of homologous recombination and cellular processes that utilize the enzymatic machinery of recombination. The chapters are written by the leading researches and cover a broad range of topics from the basic molecular mechanisms of recombinational proteins and enzymes to emerging cellular techniques and drug discovery efforts.
contributions by the leading experts in the field of DNA repair, recombination, replication and genome stability
documents cutting edge methods
Автор: Lee Tom Название: DNA Replication: Procedures and Applications ISBN: 1632391538 ISBN-13(EAN): 9781632391537 Издательство: Random House (USA) Цена: 10116.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book outlines and reviews the present condition of knowledge on numerous crucial aspects of the DNA replication procedure. DNA replication is a basic part of the life cycle of all the organisms. Many characteristics of this process show thorough conservation across organisms in all domains of life. DNA replication is a crucial process in both development and growth and in relation to a wide variety of pathological conditions including cancer. The book contains novel insights into the whole process of DNA replication under these sections: "Replication of Organellar Chromosome", "Chromatin and Epigenetic Influences" and "Telomeres". The topics provide the basis for thought provoking questions and summaries to give way to future investigations.
Название: Innovations in government ISBN: 0815713770 ISBN-13(EAN): 9780815713777 Издательство: Rowman & Littlefield Publishers Рейтинг: Цена: 4222.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
The Innovations in American Government Awards Program began in 1985 with a grant from the Ford Foundation to the Kennedy School of Government at Harvard to conduct a program of awards for innovations in state and local government. The foundation's objective was ambitious and, in an era of "government is the problem" rhetoric, determinedly proactive. It sought to counter declining public confidence in government by highlighting innovative and effective programs. Over twenty years later, research, recognition, and replication are the source of the program's continuing influence and its vitality. What is the future of government innovation? How can innovation enhance the quality of life for citizens and strengthen democratic governance? Innovations in Government: Research, Recognition, and Replication answers these questions by presenting a comprehensive approach to advancing the practice and study of innovation in government. The authors discuss new research on innovation, explore the impact of several programs that recognize innovation, and consider challenges to the replication of innovations. Contributors include Eugene Bardach (University of California- Berkeley), Robert Behn (Harvard University), John D. Donahue (Harvard University), Marta Ferreira Santos Farah (Center for Public Administration and Government, Fundacao Getulio Vargas), Archon Fung (Harvard University), Jean Hartley (University of Warwick), Steven Kelman (Harvard University), Gowher Rizvi (Ash Institute for Democratic Governance and Innovation, Harvard University), Peter Spink (Center for Public Administration and Government, Fundacao Getulio Vargas), and Jonathan Walters (Governing).
Автор: Boszormenyi Zoltan Название: PostgreSQL Replication ISBN: 1849516723 ISBN-13(EAN): 9781849516723 Издательство: Неизвестно Рейтинг: Цена: 6896.00 р. Наличие на складе: Нет в наличии.
Описание: Veeam provides data protection for modern-day technical organizations. This book takes you through installation best practices, optimizations, and the 3-2-1-1-0 rule, before going on to examine repository and proxy-related topics and advanced concepts such as CDP, extended object storage support, Veeam ONE enhancement, and Orchestrator.
