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Crispr/cas9 system: applications and technology, 


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Название:  Crispr/cas9 system: applications and technology
ISBN: 9781536164268
Издательство: Nova Science
Классификация:

ISBN-10: 1536164267
Обложка/Формат: Paperback
Страницы: 180
Вес: 0.27 кг.
Дата издания: 30.08.2019
Серия: Biology
Язык: English
Размер: 154 x 228 x 16
Ключевые слова: Genetics (non-medical)
Подзаголовок: Applications and technology
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Поставляется из: Англии
Описание: This compilation focuses on the CRISPR/Cas9 system, a genome editing tool that has been hailed as the most profound molecular biology discovery in the past decade. By employing the natural process of bacterial immunity towards bacteriophages, the tool allows researchers to precisely excise and edit parts of the genetic sequence to modify them. The authors summarize the molecular pathogenesis of hepatocellular carcinoma, available treatments/drugs and their limitations, the landscape of CRISPR targeting hepatocellular carcinoma, limitations and potential targets in future. The closing review summarises the use of CRISPR/Cas9 gene editing in ophthalmology and focuses on the advancement of gene editing in the cornea. The majority of corneal dystrophies are the result an autosomal dominant inheritance pattern within the TGFBI gene, which presents an ideal model suited for a CRISPR/Cas9 knock out methodology.


CRISPR : methods and protocols

Автор: Magnus Lundgren
Название: CRISPR : methods and protocols
ISBN: 1493926861 ISBN-13(EAN): 9781493926862
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This volume presents a list of cutting-edge protocols for the study of CRISPR-Cas defense systems and their applications at the genomic, genetic, biochemical and structural levels. CRISPR: Methods and Protocols guides readers through techniques that have been developed specifically for the analysis of CRISPR-Cas and techniques adapted from standard protocols of DNA, RNA and protein biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, CRISPR: Methods and Protocols provides a broad list of tools and techniques to study the interdisciplinary aspects of the prokaryotic CRISPR-Cas defense systems.

Plant Genome Editing with Crispr Systems: Methods and Protocols

Автор: Qi Yiping
Название: Plant Genome Editing with Crispr Systems: Methods and Protocols
ISBN: 1493989901 ISBN-13(EAN): 9781493989904
Издательство: Springer
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Цена: 32142.00 р.
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Описание: This volume provides readers with wide-ranging coverage of CRISPR systems and their applications in various plant species. The chapters in this book discuss topics such as plant DNA repair and genome editing; analysis of CRISPR-induced mutations; multiplexed CRISPR/Cas9 systems; CRISPR-Cas12a (Cpf1) editing systems; and non-agrobacterium based CRISPR delivery systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and thorough, Plant Genome Editing with CRISPR Systems: Methods and Protocols is a valuable resource for any researcher interested in learning about and using CRISPR systems in plants.

Precision Medicine, CRISPR, and Genome Engineering

Автор: Stephen Tsang; George M. Church
Название: Precision Medicine, CRISPR, and Genome Engineering
ISBN: 331963903X ISBN-13(EAN): 9783319639031
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine.


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