Forensic dna profiling, Bright, Jo-anne Coble, Michael

Автор: J?rg Epplen; Thomas Lubjuhnn
Название: DNA Profiling and DNA Fingerprinting
ISBN: 3764360186 ISBN-13(EAN): 9783764360184
Издательство: Springer
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Цена: 13060.00 р.
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Описание: This text reflects practical approaches to answering a variety of biological and medical questions, using DNA fingerprinting and genetic profiling in a broad sense that also includes statistical evaluation of the data. The book is aimed at students as well as academic teachers and researchers.

Автор: Robert Gr?tzmann; Christian Pilarsky
Название: Cancer Gene Profiling
ISBN: 1493932039 ISBN-13(EAN): 9781493932030
Издательство: Springer
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Цена: 19564.00 р.
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Описание: Cancer Gene Profiling

Автор: Mathias Munschauer
Название: High-Resolution Profiling of Protein-RNA Interactions
ISBN: 3319368486 ISBN-13(EAN): 9783319368481
Издательство: Springer
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Цена: 14365.00 р.
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Описание: The book describes how the study of a single RNA-binding protein and its interaction sites led to the development of the novel `protein occupancy profiling` technology that for the first time captured the mRNA sequence space contacted by the ensemble of expressed RNA binders.

Название: Risk Profiling in Genomics
ISBN: 0367356694 ISBN-13(EAN): 9780367356699
Издательство: Taylor&Francis
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Цена: 22202.00 р.
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Описание: This volume presents the ethical implications of risk information as related to genetics and other health data for policy decisions at clinical, research and societal levels. It will be of great interest to students and scholars of theoretical and clinical medical ethics, medical sociology, risk communication and ethics of risk.

Автор: Mathias Munschauer
Название: High-Resolution Profiling of Protein-RNA Interactions
ISBN: 3319162527 ISBN-13(EAN): 9783319162522
Издательство: Springer
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Цена: 18167.00 р.
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Описание: The work reported in this book represents an excellent example of how creative experimentation and technology development, complemented by computational data analysis, can yield important insights that further our understanding of biological entities from a systems perspective. The book describes how the study of a single RNA-binding protein and its interaction sites led to the development of the novel ‘protein occupancy profiling’ technology that for the first time captured the mRNA sequence space contacted by the ensemble of expressed RNA binders. Application of protein occupancy profiling to eukaryotic cells revealed that extensive sequence stretches in 3’ UTRs can be contacted by RBPs and that evolutionary conservation as well as negative selection act on protein-RNA contact sites, suggesting functional importance. Comparative analysis of the RBP-bound sequence space has the potential to unravel putative cis-acting RNA elements without a priori knowledge of the bound regulators. Here, Dr. Munschauer provides a comprehensive introduction to the field of post-transcriptional gene regulation, examines state-of-the-art technologies, and combines the conclusions from several journal articles into a coherent and logical story from the frontiers of systems-biology inspired life science. This thesis, submitted to the Department of Biology, Chemistry and Pharmacy at Freie Universit?t Berlin, was selected as outstanding work by the Berlin Institute for Medical Systems Biology at the Max-Delbrueck Center for Molecular Medicine, Germany.

Автор: Rani
Название: MicroRNA Profiling
ISBN: 1493965220 ISBN-13(EAN): 9781493965229
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This volume includes comprehensive descriptions of miRNA biogenesis and their role in the development and progression of various human diseases. The first few chapters of MicroRNA Profiling: Methods and Protocols discuss the effects of over-expressing and repressing of a target miRNA and their effects on cell viability and proliferation. The next few chapters explore the protocols for total RNA isolation from cells and cell-derived product including formalin fixed paraffin embedded tissue and plant tissue. The last few chapters discuss isolation and characterization of exosomes from medium conditioned by cell lines, serum, and plasma specimens. This book also includes discussions of several software tools, such as miRandola, PicTar, DIANA, and miRWalk. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and cutting-edge, MicroRNA Profiling: Methods and Protocols is a valuable resource for anyone interested in the field of Micro RNAs.