Автор: K. Okita Название: HCV/Oxidative Stress and Liver Disease ISBN: 4431670076 ISBN-13(EAN): 9784431670070 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume containing the proceedings of the 13th Yamaguchi Symposium on Liver Disease includes discussion of the direct cellular effects of hepatitis C virus (HCV) proteins on hepatocytes and reviews evidence that oxidative stress caused primarily by the HCV core protein plays a key role in disease pathogenesis.
Автор: Armstrong Donald Название: Oxidative Stress Biomarkers and Antioxidant Protocols ISBN: 0896038505 ISBN-13(EAN): 9780896038509 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Donald Armstrong updates and expands his highly praised Free Radical and Antioxidant Protocols (Humana, 1998) with a collection of new and valuable methods for evaluating the pertubations in cell function resulting from increased oxidative stress. Presented in a user-friendly, step-by-step format, these readily reproducible techniques cover both free radical-derived and antioxidant biomarkers. The methodologies demonstrated include ELISA, HPLC, infrared spectroscopy, gas chromatography-mass spectroscopy, immunoblotting, electroelution fractionation, isoelectric focusing, voltametry, and electron paramagnetic resonance imaging. Special emphasis is given to the separation of complex mixtures of plant antioxidants, soft drug design to protect from toxic oxidative metabolites, in vitro oxidation conditions, and correcting for random measurement error to improve statistical interpretation. A soon-to-be-published companion volume, Oxidants and Antioxidants: Ultrastructural and Molecular Biology Protocols (0-89603-851-3), contains state-of-the-art molecular and ultrastructural methods that expand the total number of protocols to 109 assays.
Автор: Ursula Jakob; Dana Reichmann Название: Oxidative Stress and Redox Regulation ISBN: 9400794444 ISBN-13(EAN): 9789400794443 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book examines how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.
Автор: Chakraborti Sajal, Chakraborti Tapati, Das Salil Kumar Название: Oxidative Stress in Lung Diseases: Volume 1 ISBN: 9811384126 ISBN-13(EAN): 9789811384127 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This first volume of the comprehensive, two-volume work on oxidative stress in lung disease introduces the molecular mechanisms, and the role of oxidants in the progression of different lung diseases. The lungs of humans and animals are under constant threat from oxidants from either endogenous (e.g. in situ metabolic reactions) or exogenous sources (e.g. air pollutants). Further, oxidative stress causes the oxidation of proteins, DNA and lipids, which in turn generates secondary metabolic products. The book consists of sections, each focusing on different aspects of oxidant-mediated lung diseases. As such it is a unique reference resource for postgraduate students, biomedical researchers and also for the clinicians who are interested in studying and understanding oxidant-mediated lung diseases. The second volume will incorporate other aspects of oxidant-mediated lung diseases, including prevention and therapeutics.
Автор: Chakraborti Название: Oxidative Stress in Lung Diseases ISBN: 9813293659 ISBN-13(EAN): 9789813293656 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
A. General Aspects of reactive oxygen species-mediated lung diseases
1. "Pathology of lung diseases affected by oxidative stress"
2. "Approach of smoke-related lung damage"
3. "The state of art of NADPH Oxidase-dependent oxidative stress in lung diseases"
4. "Effects of radicals on pulmonary surfactant and role of lipid in this scenario"
5. "Infection induced oxidation and DNA repair"
6. "Oxidative stress in experimental models of acute lung injury" 7. "Oxidative Lipidomics of Lung Diseases"
B. Chronic lung diseases
8. "Oxidative stress in Lung Fibrosis"
9. "Oxidative Stress Biomarkers in COPD"
10. "Oxidative stress in emphysema"
11. "Oxidative stress induced mitochondrial dysfunction and asthma"
12. "Oxidative stress in asthma and COPD"
D. Other lung diseases
13. "Oxidative stress in environmental lung diseases"
14. "Bronchopulmonary dysplasia and oxidative stress in preterm newborns"
15. "Effect of exogeneous chemical exposure on oxidative stress induced lung diseases"
16. "Pulmonary antioxidant system in acute and chronic lung injury, pulmonary fibrosis in diabetes"
17."Mitochondrial alterations and oxidative stress in cystic fibrosis"
E. Prevention and therapeutics
18. "Flagellin/Toll-like receptor 5 response was specifically attenuated by keratin sulfate disaccharide via decreased EGFR phosphorylation in human bronchial epithelial cells"\
19. "Therapeutic targeting of oxidative stress and inflammation in COPD and asthma: Pharmacological intervention with phytochemicals"
20. "ROS: modulator of therapeutic response in non-small cell lung cancer (NSCLC)"
21. "Arsenic-induced lung injury in rats and its reversal by a garlic polysulfide"
22. "The Mitochondria-targeted Drugs for Protection of Lung Damage and Pulmonary Diseases".
23. "The use of ozone as redox modulator in the treatment of chronic pulmonary disease (COPD)"
24. "Oxidative stress and therapeutic development in lung cancer"
25.The state of art of NADPH Oxidase-dependent oxidative stress in lung diseases.
26. Pharmacological modulation of ROS impairs the airway hyper responsiveness by shifting the Th1 response in allergic inflammation induced by ovalbumin
27. Flagellin/Toll-like receptor 5 response was specifically attenuated by keratin sulfate disaccharide via decreased EGFR phosphorylation in human bronchial epithelial cells.
28. Oxidative stress in experimental models of acute lung injury.
29. Pharmacokinetics, pharmacodynamics and safety of ISO1957, a preclinical candidate possessing activity against infection.
30. Rho kinase as a therapeutic target in pulmonary vascular diseases.
31. Mesenchymal stromal cell injection protects against oxidative stress in E.coli induced lung injury in mice.
32. Phosgene induced lung damage and its amelioration by cAMP elevating compounds.
Автор: Sajal Chakraborti; Tapati Chakraborti; Dhrubajyoti Название: Oxidative Stress in Microbial Diseases ISBN: 9811387621 ISBN-13(EAN): 9789811387623 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book discusses recent advances in our understanding of the role of oxidants in microbial pathophysiology, providing valuable insights into the complex role of reactive oxygen species (ROS) in host-microbial interactions. The various chapters take readers through the function of ROS in infections ranging from viral to bacterial, and describe how microorganisms have developed complex strategies to not only avoid contact with phagocyte-derived oxidants, but also protect themselves from injury when oxidants are encountered. Featuring the latest research in the field of microbial diseases, this timely book is a ready reference for scientists looking to develop new anti-microbial drugs.
Автор: Mohinder Bansal; Naveen Kaushal Название: Oxidative Stress Mechanisms and their Modulation ISBN: 8132220315 ISBN-13(EAN): 9788132220312 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Research over the years has demonstrated that free radicals mediated oxidative stress lies at the helm of almost all patho-physiological phenomena. These findings emphasize on the need to understand the underlying molecular mechanism(s) and their critical role in the pathogenesis. This book aims to focus on these areas to provide readers a comprehensive outlook about the major redox sensitive pathways and networks involved in various disease conditions. In the first chapter of the book, basic information about the oxidative stress, its generation, its biomarkers and its role in body are discussed. In the next three chapters, the role of oxidative stress in various pathologies ranging from neurological disorders, to cardiovascular diseases, cancers, metabolic diseases and ageing have been described. Chapter 5 cumulatively describes the most important molecular signaling pathways that are affected by reactive oxygen species (ROS). These are the mechanisms which are common denominators in various pathological states. In the next part of the book, various antioxidant strategies to target and mitigate ROS have been discussed with details on the mechanisms. Selenium, being the research focus and interest of the authors for years, the role of selenium as an antioxidant as part of selenoproteins has been included in the book. Finally, the book culminates with authors’ perspective on the future of the redox biology field. Throughout the book, efforts have been made to use simplified language and suitable figures for ease to understand the contents. Although the authors have tried to touch on all the different aspects of oxidative stress in detail, the fact that it is a continuously growing field with updates coming every day, there might be some areas which might not be described in depth. This book is designed for students, young scientists to get acquainted with the redox biology. Overall, this book is a reference to understand the redox regulation of cellular signaling pathways involved in pathogenesis.
Автор: Sanjay K. Srivastava Название: Role of Capsaicin in Oxidative Stress and Cancer ISBN: 9401784299 ISBN-13(EAN): 9789401784290 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress and much more.
Описание: This volume presents a unique comparative treatment of the role oxidative stress plays in vertebrates and invertebrates in multiple organ systems with regards to cell death, development, aging, and human diseases, and anti-oxidant therapy.
Автор: Tomris ?zben Название: Free Radicals, Oxidative Stress, and Antioxidants ISBN: 0306458136 ISBN-13(EAN): 9780306458132 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a NATO ASI held in Antalya, Turkey, May 24-June 4, 1997
Автор: Donald Armstrong Название: Advanced Protocols in Oxidative Stress II ISBN: 1493957031 ISBN-13(EAN): 9781493957033 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This second volume of Advanced Protocols in Oxidative Stress focuses on novel techniques for detecting ROS/RNS, unique AOX technology and applications, gene expression and biostatistics for evaluating OS-derived experimental data.
Автор: Donald Armstrong Название: Advanced Protocols in Oxidative Stress III ISBN: 1493914405 ISBN-13(EAN): 9781493914401 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Advanced Protocols in Oxidative Stress III continues the thread of the first two books by covering technology ranging from a portable hand-held detector for remote analysis of antioxidant capacity to sophisticated technology such as shotgun lipidomics, mitochondrial imaging, nano sensors, fluorescent probes, chromatographic fingerprints, computational models and bio statistical applications. Several chapters have shown the effect of pro-oxidation and antioxidants as inflammatory mediators in signaling pathways leading from the initial stimulus to termination through redox cycles. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Advanced Protocols in Oxidative Stress III offers to save investigators significant time and effort, allowing them to focus on their own personal topic of interest.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
