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Genetics of Rare Autoimmune Diseases, Mart?n


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Автор: Mart?n
Название:  Genetics of Rare Autoimmune Diseases
ISBN: 9783030039332
Издательство: Springer
Классификация:



ISBN-10: 3030039331
Обложка/Формат: Hardcover
Страницы: 240
Вес: 0.63 кг.
Дата издания: 2019
Серия: Rare Diseases of the Immune System
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 10 illustrations, color; 2 illustrations, black and white; viii, 240 p. 12 illus., 10 illus. in color.
Размер: 238 x 162 x 14
Читательская аудитория: Professional & vocational
Основная тема: Rheumatology
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The main aim of this volume is to provide an updated overview of the genetic basis of a group of complex disorders that are considered rare individually, but show a relatively high prevalence on the whole in developed countries: the rare autoimmune diseases. These are chronic disorders that involve long and expensive treatments with considerable side effects that may dramatically reduce the quality of life of affected people. Therefore, shedding light into their pathologic mechanisms is a major concern given their growing social and economic awareness and impact.

General sections include different chapters on single entities as systemic lupus and sclerosis, Behcets disease, Sjogrens syndrome and polymiositis, and sections devoted to autoimmune vasculitis, hepatic autoimmune conditions, as well as those affecting the nervous system, and a concluding chapter in which the shared predisposition amongst all diseases is discussed. All the chapters are given a homogeneous scheme in which the authors explain the clinical singularities of every disease and report the recent breakthrough discoveries related to them, giving a critical interpretation and suggesting future perspectives. All contributors are renowned researchers with high expertise in each disease.

Due to the exponential increase in our understanding of the genetic causes of these complex diseases, a major advance in biomedical discovery is taking place. However, most of the achievements in this field are very recent and there is a lack of bibliography gathering them together. This book is thus filling a gap and will prove a useful companion to clinicians in the first place (internists, rheumatologists, clinical immunologists, and hematologists) but also to basic and applied researchers.




Autoimmune diseases

Название: Autoimmune diseases
ISBN: 0128121025 ISBN-13(EAN): 9780128121023
Издательство: Elsevier Science
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Цена: 39582.00 р.
Наличие на складе: Поставка под заказ.

Описание: The Very Hungry Caterpillar is a classic childhood character which is not only fun and engaging but educational too! The Large Hungry Caterpillar is the perfect present for newborns upwards and works wonders as a gift on its own or when given together with Eric Carle`s international best-selling literary classic - the perfect accompaniment! This gorgeous plush gift will `eat` its way into the hearts of boys and girls of all ages the minute they set eyes on it. Perfect as a first Christmas, first birthday or Christening gift, the Large Very Hungry Caterpillar is also wonderful for marking the arrival of a new baby. It is a fun, vibrant and eye-catching addition to the nursery and the playroom.

Autoimmune diseases acute and complex situations

Автор: Khamashta Munther A., Ramos-Casals Manuel
Название: Autoimmune diseases acute and complex situations
ISBN: 0857293575 ISBN-13(EAN): 9780857293572
Издательство: Springer
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Цена: 21522.00 р. 30745.00 -30%
Наличие на складе: Есть (1 шт.)
Описание: Autoimmune Diseases: Acute and Complex Situations provides a detailed overview of conditions associated with autoimmune diseases that are considered either life-threatening or requiring complex management. These include abdominal pain, arthritis, cutaneous ulcers, gastrointestinal hemorrhage, epilepsy, pancreatitis, stroke and white-matter CNS lesions. Autoimmune Diseases: Acute and Complex Situations addresses the latest clinical and immunological prognostic factors that may help to identify patients at higher risk of developing potentially life-threatening involvement. This book comprehensively helps the reader to diagnose these patients, in whom an early therapeutic approach is essential. Autoimmune Diseases: Acute and Complex Situations is a valuable reference tool for rheumatologists, internists, immunologists, and all the specialists involved in the multidisciplinary care of patient with rheumatic and systemic autoimmune diseases.

Autoimmune Diseases

Автор: Hertl
Название: Autoimmune Diseases
ISBN: 3211835989 ISBN-13(EAN): 9783211835982
Издательство: Springer
Цена: 6848.00 р.
Наличие на складе: Поставка под заказ.

Описание: Cutaneous autoimmune diseases of the skin remain an enigma for many clinicians and scientists who are not familiar with these mostly severe and chronic diseases. The book presented provides an overview and the latest information on the broad spectrum of cutaneous autoimmune disorders for clinicians, scientists and practitioners in dermatology, medicine, rheumatology, ENT, pediatrics and ophthalmology. The book is unique since it presents the state-of-the-art knowledge on pathophysiology, clinical diagnosis and management of these disorders provided by the world experts in the field. The primary intention is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and handle these conditions. The book is illustrated with many tables, illustrative figures and clinical color photographs.

The Heart in Rheumatic, Autoimmune and Inflammatory Diseases

Автор: Nussinovitch, Udi
Название: The Heart in Rheumatic, Autoimmune and Inflammatory Diseases
ISBN: 0128032677 ISBN-13(EAN): 9780128032671
Издательство: Elsevier Science
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Цена: 21054.00 р.
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Описание:

The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives.

This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe.

  • A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases.
  • Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches.
  • Presents an up-to-date "level of evidence" and "strengths of recommendations" for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.
Autoimmune Diseases of the Skin

Автор: Michael Hertl
Название: Autoimmune Diseases of the Skin
ISBN: 3709119057 ISBN-13(EAN): 9783709119051
Издательство: Springer
Рейтинг:
Цена: 18167.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Autoimmune disorders of the skin remain an enigma for many clinicians and scientists not familiar with these mostly severe and chronic diseases. The book provides an overview and the latest information on the broad spectrum of cutaneous autoimmune disorders for clinicians, scientists and practitioners in dermatology, medicine, rheumatology, ENT, pediatrics and ophthalmology. The book is unique since it presents the state-of-the-art knowledge on pathophysiology, clinical diagnosis and management of these disorders provided by the world experts in the field. The primary intention is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and handle these conditions. The book is illustrated with many tables, illustrative figures and clinical color photographs. The third edition has been thoroughly updated and extended by chapters on paraneoplastic cutaneous syndromes, atopic dermatitis and autoimmunity and Skin manifestations of rheumatic diseases.

Immunopharmacology in Autoimmune Diseases and Transplantation

Автор: L. Endresen; ?. F?rre; H.E. Rugstad
Название: Immunopharmacology in Autoimmune Diseases and Transplantation
ISBN: 1489911693 ISBN-13(EAN): 9781489911698
Издательство: Springer
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Цена: 27950.00 р.
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Описание: The specific disease section also covers rare situations, fluctuations in disease patterns, and subgroups of patients and immunophar- macological treatment in these situations.

The Heart in Systemic Autoimmune Diseases,14

Автор: Atzeni, Fabiola
Название: The Heart in Systemic Autoimmune Diseases,14
ISBN: 0128039973 ISBN-13(EAN): 9780128039977
Издательство: Elsevier Science
Рейтинг:
Цена: 21559.00 р.
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Описание:

The Heart in Systemic Autoimmune Diseases, Second Edition, provides an overview on our current understanding of major complications relating to the heart and autoimmune diseases. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations of these important comortbidities. Mortality in autoimmune diseases, in particular, rheumatoid arthritis and SLE, has increased when compared with the general population. This excess mortality is largely due to cardiovascular diseases (CVDs)-particularly those of atherosclerotic origin, such as ischemic heart disease-and is gaining recognition in all branches of medicine, from cardiology, to internal medicine, and from rheumatologists to orthopedics.

An Epidemic of Absence: A New Way of Understanding Allergies and Autoimmune Diseases

Автор: Velasquez-Manoff Moises
Название: An Epidemic of Absence: A New Way of Understanding Allergies and Autoimmune Diseases
ISBN: 1439199396 ISBN-13(EAN): 9781439199398
Издательство: Simon & Schuster
Цена: 2298.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: From asthma to Crohn s disease, everyone knows someone who suffers from an allergic or autoimmune disorder. And if it appears that the prevalence of these maladies has increased recently, that s because it has to levels never before seen in human history. These days no fewer than one in five and likely more Americans suffers from one of these ailments. We seem newly, and bafflingly, vulnerable to immune system malfunction. Why? One possibility is that we have systematically cleaned ourselves to illness; this belief challenges deeply entrenched notions about the value of societal hygiene and the harmful nature of microbes. Yet scientists investigating the rampant immune dysfunction in the developed world have inevitably arrived at this conclusion. To address this global epidemic of absence, they must restore the human ecosystem.
This groundbreaking book explores the promising but controversial worm therapy deliberate infection with parasitic worms in development to treat autoimmune disease. It explains why farmers children so rarely get hay fever, why allergy is less prevalent in former Eastern Bloc countries, and how one cancer-causing bacterium may be good for us. It probes the link between autism and a dysfunctional immune system. It investigates the newly apparent fetal origins of allergic disease that a mother s inflammatory response imprints on her unborn child, tipping the scales toward allergy.
"An Epidemic of Absence" is a brilliant, cutting-edge exploration of the dramatic rise of allergic and autoimmune diseases and the controversial, potentially groundbreaking therapies that scientists are developing to correct these disorders."

Microorganisms and Autoimmune Diseases

Автор: Herman Friedman; Noel R. Rose; Mauro Bendinelli
Название: Microorganisms and Autoimmune Diseases
ISBN: 146138009X ISBN-13(EAN): 9781461380092
Издательство: Springer
Рейтинг:
Цена: 6986.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Experts in microbiology and autoimmunity examine the association between microorganisms and the development of specific categories of autoimmune diseases. Subsequent chapters describe the role of viruses in the induction of these diseases and of diseases with an autoimmune component.

Autoimmune Diseases: Clinical Theory

Автор: Ward Marcy
Название: Autoimmune Diseases: Clinical Theory
ISBN: 1632410524 ISBN-13(EAN): 9781632410528
Издательство: Неизвестно
Цена: 18507.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Autoimmune Disorders, a heterogeneous and multifaceted group of diseases, affect virtually any organ of the human body. This book intends to present currently accessible manifestations by providing an etiopathogenetic overview of both systemic and organ d

Autoimmune Diseases & Treatment: Organ-Specific and Systemic Disorders. 2005

Автор: Shoenfeld
Название: Autoimmune Diseases & Treatment: Organ-Specific and Systemic Disorders. 2005
ISBN: 157331613X ISBN-13(EAN): 9781573316132
Издательство: Wiley
Рейтинг:
Цена: 18770.00 р.
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Описание: Only in very recent times have therapies been developed that are specific to a particular manifestation of autoimmune disease, and these have begun to replace the all-purpose remedies of the past 30 years.

Cytokines and Autoimmune Diseases

Автор: Vijay K. Kuchroo; Nora Sarvetnick; David A. Hafler
Название: Cytokines and Autoimmune Diseases
ISBN: 1617372250 ISBN-13(EAN): 9781617372254
Издательство: Springer
Рейтинг:
Цена: 25853.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases.


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