Prognostic and therapeutic applications of rkip in cancer,
Автор: Antonio Russo; Stefano Iacobelli; Juan Iovanna Название: Diagnostic, Prognostic and Therapeutic Value of Gene Signatures ISBN: 1493962590 ISBN-13(EAN): 9781493962594 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Gene expression studies have revealed diagnostic profiles and upregulation of specific pathways in many solid tumors. The explosion of new information in gene expression profiling could potentially lead to the development of tailored treatments in many solid tumors. In addition many studies are ongoing to validate these signatures also in predicting response to hormonal, chemotherapeutic and targeted agents in breast cancer as well as in other tumors. Diagnostic, Prognostic and Therapeutic Value of Gene Signatures provides readers a useful and comprehensive resource about the range of applications of microarray technology in oncological diseases. Topics covered include gene signatures and soft tissue sarcomas, prognostic relevance of breast cancer signatures, gene expression profiling of colorectal cancer and liver metastasis, gene signatures in GISTs, CNVs and gene expression profiles in pancreatic cancer, and gene signatures in head/neck, lung and gastric tumors. Diagnostic, Prognostic and Therapeutic Value of Gene Signatures will be of great value to residents and fellows, physicians, pathologists and medical oncologists.
Автор: Walker Название: Prognostic and Predictive Factors in Breast Cancer 2E ISBN: 0415422256 ISBN-13(EAN): 9780415422253 Издательство: Taylor&Francis Рейтинг: Цена: 26796.00 р. Наличие на складе: Поставка под заказ.
Описание: The first edition of this groundbreaking text established itself as the definitive reference on a topic of extreme interest and relevance to those involved in breast cancer management.This new Second Edition is filled with over 250 full-color images, illustrations, and photographs, and showcases cutting-edge translational research not included in the first edition. The broader scope of information in this text is essential reading for gynecologic surgeons, oncologists, pathologists, and molecular biologists.
Автор: Gospodarowicz Название: Prognostic Factors in Cancer. 3ed. 2006 ISBN: 0470038012 ISBN-13(EAN): 9780470038017 Издательство: Wiley Рейтинг: Цена: 17574.00 р. Наличие на складе: Поставка под заказ.
Описание: Prognostic Factors in Cancer, Third Edition examines the prognostic factors associated with each cancer site and provides insight into potential treatments and therapies.
Описание: Discussing the methodologies involved in measuring and reporting, this book reviews the latest research from international regarding the identification of markers typing breast cancer behavior. It also examines the roles of major predictive markers such as the steroid receptors, p53, and HER-2. The book provides an overview of the prognostic and predictive factors, the role of the pathologist in prognostic factors, determination of occult auxiliary lymph node metastases, and risk factors for recurrence. That focus makes this text extremely useful for oncologists and researchers who want to learn more about best practices in prognoses.
Diagnostic and Therapeutic Applications of Exosomes in Cancer evaluates the potential of exosome content manipulation in the development of novel therapeutics. In recent years, exosomes, the small vesicles produced by all cell types, have been identified as contributors to cancer growth and metastasis. However, due to their unique biophysical properties, they are also being tested for use in therapeutic design and delivery, as well as in diagnostics. This book presents a comprehensive analysis on exosomes, with a main emphasis on their biogenesis and signaling, use as biomarkers, and as tools for imaging, drug delivery and the treatment of cancer.
Covers emerging pharmaceutical and diagnostic applications, including exosomes being tested as carriers of anticancer drugs, ongoing clinical trials, and exosomes as imaging agents for cancer diagnosis and treatment
Brings together a team of highly regarded international authors who provide a full-rounded analysis
Presents comprehensive coverage of the unique biophysical properties of exosomes
Explores current and future possibilities
Автор: Hideo Kimura Название: Hydrogen Sulfide and its Therapeutic Applications ISBN: 370911974X ISBN-13(EAN): 9783709119747 Издательство: Springer Рейтинг: Цена: 16070.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The metabolism of sulfur especially by sulfurtransferases had been intensively studied in mid 1900’s. Three enzymes, cystathionine ?–synthase (CBS), cystathionine ?–lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3MST) were found to have the capacity to produce H2S in vitro. However, H2S was recognized simply as a by-product of the metabolic pathways or as a marker for evaluating the activity of enzymes rather than as a physiological active molecule. In the late 1980’s relatively high concentrations of sulfide were measured in the brain that led to the successive studies of identifying the physiological functions of H2S. Recently, the steady-state concentrations of H2S have been re-evaluated and found to be much less than that initially measured. However, despite these differences, such re-evaluations served to further confirm the existence of H2S in mammalian tissues. H2S is produced in almost every organ and plays various roles such as neuromodulation, vasodilation, insulin release, inflammation, angiogenesis and cytoprotection. The unregulated production of H2S and improper responses of target molecules are involved in the pathogenesis of various diseases. This book focuses on these topics as well as on the recent progress in the biology and the therapeutic development of this molecule.
Автор: Paul Hermanek; Mary K. Gospodarowicz; Donald E. He Название: Prognostic Factors in Cancer ISBN: 3540586881 ISBN-13(EAN): 9783540586883 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This compilation represents the first phase of a more extensive process to integrate all prognostic factors in cancer to further enhance the prediction of outcome following treatment. Importance of Prognostic Factors Prognostic factors in cancer often have an immense influence on outcome, while treatment often has a much weaker effect.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
