The Hypothalamic-Pituitary-Adrenal Axis in Health and Disease, Eliza B. Geer
Автор: Laws Название: Pituitary Disorders: Diagnosis and Management ISBN: 0470672013 ISBN-13(EAN): 9780470672013 Издательство: Wiley Рейтинг: Цена: 11415.00 р. 16307.00-30% Наличие на складе: Есть (1 шт.) Описание: This book is a highly clinical and practical resource for endocrinologists of all levels managing patients daily, as well as primary care physicians who are often the first port of call before patient referral. It guides the reader through each pituitary disorder, including those specific to men, women and children.
Описание: Truly unique cutting edge state of the art information on basic and clinical research.
A great help for the clinician to diagnose and treat this uncommon hormone resistance. Basic scientists learn how much has been discovered on the mechanism of hormone action from the mutations of the various genes involved to thyroid hormones and TSH.
Автор: Felipe F. Casanueva; Ezio Ghigo Название: Hypothalamic-Pituitary Diseases ISBN: 3319444441 ISBN-13(EAN): 9783319444444 Издательство: Springer Рейтинг: Цена: 48913.00 р. Наличие на складе: Поставка под заказ.
Описание: This book presents the state of the art in the pathophysiology, diagnosis, and therapy of hypothalamic and pituitary disorders. After an introduction devoted to the physiology of the neuroendocrine control of the hypothalamic-pituitary unit, the diverse disorders involving hormonal excess or deficiency are systematically addressed axis by axis. For each disorder, pathophysiology, clinical presentation, and management are discussed in detail. In addition, individual chapters focus on the neuroendocrinology of energy homeostasis and of bone metabolism, metabolic derangement secondary to pituitary dysfunction, and pituitary control of the endocrine pancreas. While the focus of the book is predominantly on pathophysiological and clinical aspects, due attention is also devoted to potential diagnostic and therapeutic innovations. The book is intended as a major reference for endocrinologists and basic and clinical scientists.
Автор: Felix G. Sulman; M. Ben-David Название: Hypothalamic Control of Lactation ISBN: 3642462359 ISBN-13(EAN): 9783642462351 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The contents of this monograph "Hypothalamic Control of Lacta- tion" are the result of studies by a nine-man team which has worked together for nine years. The topic is so fascinating that new research students are attracted to it every year, and the circle is growing steadily. This is, in fact, part of a much more extensive research field to which our Department is applying itself at present, viz. "Hypo- thalamic Pharmacology." Our work in this sphere was made possible by a generous grant from the United States Department of Agriculture, which helped us during the first 5 years of research with Grant No. FG-IS-147, Project No. A10-AH-3, and recently with another grant for a further 5-year period, No. FG-IS-259, Project No. A10-AH-33. Our thanks are due to Dr. JOEL BITMAN, Hormone Physiology Leader of the USDA Agri- cultural Research Service at Beltsville, Md., the sponsor of this research. As this monograph contains mainly references connected with our own work, the reader who wishes to make a survey of lactation should study the references cited in the bibliography, such as COWIE (1961, 1966), COWIE and FOLLEY (1957, 1961), FOLLEY (1952, 1956), JACOB- SOHN (1961), LYONS and DIXON (1966), MEITES (1959a, 1961, 1966), MEITES and NICOLL (1966).
Автор: Kurt, Gizem Woodworth, Hillary L. Leinninger, Gina M. Название: Lateral hypothalamic control of energy balance ISBN: 1615047654 ISBN-13(EAN): 9781615047659 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 5637.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Food and water are necessary for survival, but can only be obtained via ingestive behavior (feeding, drinking, and moving). Survival thus depends on the ability of the brain to coordinate the need for water and energy with appropriate behaviors to modify their intake as necessary for homeostasis. However, the balance of these behaviors also inherently determines body weight, and imbalances contribute to the development of weight disorders, such as obesity and anorexia nervosa. The lateral hypothalamic area (LHA) of the brain is anatomically positioned to coordinate the sensation of osmotic and energy status with goal-directed ingestive behaviors necessary to maintain homeostasis and body weight, and, hence, may hold insight into the potential treatment for energy balance disorders. This volume reviews the essential role of the LHA for the control of body weight, from its historical description as a ""feeding center"" to the current view of this LHA as a cellularly heterogeneous hub that regulates multiple aspects of physiology to influence body weight. Furthermore, we evaluate how specific LHA populations coordinate certain metabolic cues and behaviors, which may guide the development of pathway-specific interventions to improve the treatment of energy balance disorders.
Автор: Gizem Kurt, Hillary L. Woodworth, Gina M. Leinninger Название: Lateral Hypothalamic Control of Energy Balance ISBN: 1615047670 ISBN-13(EAN): 9781615047673 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 8772.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Reviews the essential role of the lateral hypothalamic area (LHA) for the control of body weight, from its historical description as a "feeding centre" to the current view of this LHA as a cellularly heterogeneous hub that regulates multiple aspects of physiology to influence body weight. The authors also evaluate how specific LHA populations coordinate certain metabolic cues and behaviours.
Описание: In The Pituitary Gland and Adrenal Glands: New Research, the authors first discuss pituicytomas, rare primary glial neoplasms that arise in the neurohypophysis (or posterior portion) of the pituitary gland. They typically present with signs and symptoms of a slow growing, non-hormonally active mass of the sellar and suprasellar region, compressing adjacent structures. Following this, the clinical and pathologic features of spindle cell oncocytomas are discussed. Spindle cell oncocytomas are rare tumors, accounting for less than 0.5% of sellar masses. Tumors typically present in adults and most commonly manifest with visual disturbances and pituitary hypofunction. Additionally, the authors review the clinical and pathological features of gangliocytomas, rare benign tumors of the neuroaxis. They are most commonly seen in children and young adults, and most often arise in the cerebellum as part of Cowdens disease, or in the sellar region. The clinicopathologic features of granular tumors, rare neoplasms that most commonly arise in the neurohypophysis or posterior portion of the pituitary gland, are also discussed. This compilation goes on to examine the adrenal glands, paired structures located superior to the kidneys in the retroperitoneal space. Mineralocorticoids, glucocorticoids and adrenal androgens are synthesized respectively in the zona glomerulosa, zona fasciculatis and zona reticularis that make up the cortex, while the inner adrenal medulla produces the catecholamines and peptides. The risk of developing adrenal insufficiency among glucocorticoid users is assessed, and risk factors are identified. Glucocorticoids are widely used for the treatment of various inflammatory conditions and malignancies, as well as after organ transplantation. The closing study explores hypothalamic-pituitary-adrenal axis activation, a potent and complex response to heat stress in domestic livestock. The hypothalamic-pituitary-adrenal axis is activated during stress, which leads to the secretion of cortisol and aldosterone from the adrenal gland.
Автор: E. V. Naumenko Название: Central Regulation of the Pituitary-Adrenal Complex ISBN: 1468416162 ISBN-13(EAN): 9781468416169 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This monograph gives an up-to-date account of the original results of the author`s research in the complex field of the central control over relationships which have become established in the course of evolution between the hypothalamus and the pituitary gland.
Описание: In recent years, a considerable amount of effort has been devoted, both in industry and academia, towards the behavioral modeling, evaluation and prediction of the hypothalamus pituitary thyroid system.Thyroid Systems Engineering targets an optimal treatment of people suffering from thyroid hormone disorders. The content is motivated by in-depth observations of such patients whose rich data supported the theoretical framework arising from formal mathematical reasoning, guided by the nature of thyroid physiology. Leveraging on the insights emerging from the unique combination of an electrical engineer working with a clinical thyroidologist, and both being scientists skilled in mathematics, the authors introduce this new discipline and field of scientific investigation aptly designated as Thyroid Systems Engineering.Readers will discover that mathematics can indeed model the behavior of the hypothalamus-pituitary-thyroid (HPT) axis. Focused on modeling, each of the eighteen chapters gives the reader a notion of the application of relevant mathematics to pertinent issues encountered in mainstream thyroidology. Many cellular processes resemble the flux of variables and states in a complex multi-parameter space through time analogous to current flow in electrical networks. It is then logical to apply the principles and physical laws of electrodynamics, electrical network theory, control systems theory and signal theory to many of the biological phenomena encountered in endocrinology. Such an approach is used liberally throughout the book and successfully yields elegant solutions to a number of models presented within.This book can serve as a reference to mathematical modeling in other aspects of endocrine physiology, and as the starting point for a fundamental course in medical modeling. It will appeal to postgraduates in electrical engineering, academic physicians and biomedical researchers. Further, readers equipped with advanced calculus, electrical network theory, control theory and signal theory should be able to follow the mathematical expositions that describe thyrotropic control. They represent a new discipline based on mathematical modeling in physiology applicable to medical diagnostics, measurement and treatment to cooperate in the clinical team and realize an optimized treatment for patients.
Автор: Melmed, Shlomo Название: The Pituitary ISBN: 0128041692 ISBN-13(EAN): 9780128041697 Издательство: Elsevier Science Рейтинг: Цена: 26444.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions. This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new edition has been extensively revised to reflect new knowledge derived from advances in molecular and cell biology, biochemistry, diagnostics, and therapeutics as they apply to the pituitary gland. . The wide spectrum of clinical disorders emanating from dysfunction of the master gland is described in detail by experts in the field. Fundamental mechanisms underlying disease pathogenesis are presented to provide the reader with an in-depth understanding of mechanisms subserving both normal and disordered pituitary hormone secretion and action. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. Chapters provide medical students, clinical and basic endocrinology trainees, endocrinologists, internists, pediatricians, gynecologists, and neurosurgeons with a comprehensive, yet integrated, text devoted to the science and art of pituitary medicine.
Автор: Margaret E. Wierman Название: Diseases of the Pituitary ISBN: 0896033643 ISBN-13(EAN): 9780896033641 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Contains nineteen review articles that provide an overview of the normal function of the pituitary and of the diagnosis and treatment of pituitary disorders. This title features topics that range from normal hypothalamic-pituitary interactions and the processes that disrupt them to advances in pituitary imaging.
Автор: Brooke Swearingen; Beverly M. K. Biller Название: Diagnosis and Management of Pituitary Disorders ISBN: 1617378461 ISBN-13(EAN): 9781617378461 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This text is a review of current management techniques for pituitary tumors, incorporating recent advances and discussions by experienced clinicians. The use of both endocrinologists and neurosurgeons as chapter authors allows differing perspectives to be incorporated.
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