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The CAPRISA Clinical Trials: HIV Treatment and Prevention, Quarraisha Abdool Karim; Salim S. Abdool Karim; Ch


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Цена: 19564.00р.
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Автор: Quarraisha Abdool Karim; Salim S. Abdool Karim; Ch
Название:  The CAPRISA Clinical Trials: HIV Treatment and Prevention
ISBN: 9783319837567
Издательство: Springer
Классификация:



ISBN-10: 3319837567
Обложка/Формат: Soft cover
Страницы: 243
Вес: 0.39 кг.
Дата издания: 2017
Язык: English
Издание: Softcover reprint of
Иллюстрации: 24 tables, color; 23 illustrations, color; 1 illustrations, black and white; vi, 243 p. 24 illus., 23 illus. in color.
Размер: 234 x 156 x 14
Читательская аудитория: General (us: trade)
Основная тема: Health Promotion and Disease Prevention
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Since its inception 14 years ago, CAPRISA has conducted numerous clinical studies that have influenced international TB-HIV treatment guidelines as well as HIV prevention through innovations in the microbicide and vaccine fields. This book provides a historical account of how each of CAPRISA’s high impact studies was created, developed, implemented, analysed and communicated. In doing so, the reader is taken on a journey that provides glimpses into the genesis of research ideas and how this ultimately leads to a range of HIV prevention and treatment studies that have impacted the global response to the HIV and TB epidemics.Comprised of 5 sections, the book details the following:
    HIV epidemic in South Africa and the establishment of a research centre to undertake clinical, epidemiological and laboratory research on HIV. CAPRISA’s clinical trials on HIV and HSV-2 prevention. These studies investigated the impact of tenofovir gel as topical antiretroviral pre-exposure prophylaxis (PrEP), implementation of topical PrEP through family planning clinics, conditional cash incentives for HIV prevention, HIV vaccines, and passive immunisation with broadly neutralising antibodies. CAPRISA’s research on the treatment of HIV and TB co-infection. A review of the major scientific findings from the CAPRISA studies on acute infection and genital mucosal immunology. Essential support activities for the conduct of clinical trials, including research laboratories and pharmacies, as well as establishing effective communication and sustainable structures for community engagement to maintain effective and respectful partnerships with participating communities. The book concludes with a chapter about the challenges facing future HIV prevention and treatment trials.
The CAPRISA Clinical Trials: HIV Treatment and Prevention is a resource for undergraduate and postgraduate students, health care providers, doctors, decision-makers and researchers who are seeking guidance and insights on clinical trials – their creation, conduct and impact.

Дополнительное описание:
Part I. Introduction.- Studies Linked to the Evolving HIV Epidemic in South Africa: Informing the CAPRISA Scientific Agenda.- CAPRISA: Establishing A Research Center to Undertake HIV Clinical Trials.- Overview of Clinical Trials.- Part II. CAPRISA Cl



Stroke Prevention in Clinical Practice

Автор: Baker
Название: Stroke Prevention in Clinical Practice
ISBN: 1852339640 ISBN-13(EAN): 9781852339647
Издательство: Springer
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Цена: 4890.00 р. 6986.00 -30%
Наличие на складе: Есть (1 шт.)
Описание: Stroke is a brain attack and a major cause of disability and the third biggest killer. Active intervention can prevent stroke especially in high risk groups. This work explains how to accurately diagnose a TIA, determine what investigations are indicated and how and when to intervene to reduce the risk of stroke.

Health promotion and disease prevention in clinical practice

Автор: Coviello
Название: Health promotion and disease prevention in clinical practice
ISBN: 149639996X ISBN-13(EAN): 9781496399960
Издательство: Lippincott Williams & Wilkins
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Цена: 12355.00 р.
Наличие на складе: Поставка под заказ.

Описание: The Third Edition of Health Promotion and Disease Prevention in Clinical Practice reflects a clinically-focused, team-based approach to health promotion conversations. This practical reference incorporates the latest guidelines from major organizations, including the U.S. Preventive Services Task Force, and offers a complete overview of how to help patients adopt healthy behaviors and deliver recommended screening tests and immunizations. Packed with realistic strategies throughout, it offers expert guidance on counseling patients about exercise, nutrition, tobacco use, substance use, sexually transmitted infections, depression, and more.

  • Provides sample conversations and practical strategies for preventive counseling during each stage of the patient encounter: gathering information from the patient, ordering evidence-based screenings and lab tests, designing personalized health maintenance plans, facilitating behavior change, and more.
  • Incorporates real-world guidance from experts in behavioral change in the context of limited resources, tailoring advice to different ethnic, financial, and social viewpoints.
  • Helps you identify possible environmental or lifestyle risks and help patients develop strategies for mitigating those risks.
  • Addresses the importance of providing care through a population health lens.
  • Contains updated patient resource materials and instructions.


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HIV Prevention and Treatment

Автор: Quarraisha Abdool Karim; Salim Abdool Karim; Chery
Название: HIV Prevention and Treatment
ISBN: 3319475177 ISBN-13(EAN): 9783319475172
Издательство: Springer
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Цена: 19564.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Part I. Introduction.- Studies Linked to the Evolving HIV Epidemic in South Africa: Informing the CAPRISA Scientific Agenda.- CAPRISA: Establishing A Research Center to Undertake HIV Clinical Trials.- Overview of Clinical Trials.- Part II. CAPRISA Clinical Trials for HIV and HSV-2 Prevention.- Antiretrovirals for HIV Prevention.- Rolling out of tenofovir gel in family planning clinics: the CAPRISA 008 implementation trial.- Conditional cash transfers to reduce HIV risk in young women: the CAPRISA 007 cluster randomised control trial.- HIV vaccine and passive immunity trials.- Part III: CAPRISA Clinical Trials for HIV-TB Treatment.- CAPRISA 003: Timing of antiretroviral initiation in HIV-TB co-infected patients - The SAPiT Trial.- Scaling up TB-HIV integration in public health clinics: translating research findings into practice.- Part IV: Experiences and lessons learnt from clinical trials in CAPRISA.- Lessons from the Acute Infection Study: from Bench to Bedside.- Understanding sexual HIV transmission in women by focusing on the genital mucosa.- Part V: Essential support activities for the conduct of clinical trials.- Good practices in conducting clinical trials: Good Participatory Practice, Good Pharmacy Practice and Good Laboratory Practice.- Grants Management.- Taking science to the people: communication and media strategies for clinical trials.- Looking ahead: What Does the Future Hold for CAPRISA?.- Appendix.- Index.

Treatment and Prevention of Malaria

Автор: Henry M. Staines; Sanjeev Krishna
Название: Treatment and Prevention of Malaria
ISBN: 3034808089 ISBN-13(EAN): 9783034808088
Издательство: Springer
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Цена: 26120.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs.

Exercise for Cardiovascular Disease Prevention and Treatment

Автор: Junjie Xiao
Название: Exercise for Cardiovascular Disease Prevention and Treatment
ISBN: 981104306X ISBN-13(EAN): 9789811043062
Издательство: Springer
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Цена: 23757.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice.

Negotiating Pharmaceutical Uncertainty: Women`s Agency in a South African HIV Prevention Trial

Автор: Saethre Eirik, Stadler Jonathan
Название: Negotiating Pharmaceutical Uncertainty: Women`s Agency in a South African HIV Prevention Trial
ISBN: 0826521398 ISBN-13(EAN): 9780826521392
Издательство: Mare Nostrum (Eurospan)
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Цена: 11504.00 р.
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Описание: Telling the story of a clinical trial testing an innovative gel designed to prevent women from contracting HIV, Negotiating Pharmaceutical Uncertainty provides new insight into the complex and contradictory relationship between medical researchers and their subjects.

Hepatitis Prevention and Treatment

Автор: Joseph M. Colacino; Beverly A. Heinz
Название: Hepatitis Prevention and Treatment
ISBN: 3034896174 ISBN-13(EAN): 9783034896177
Издательство: Springer
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Цена: 20962.00 р.
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Описание:

Chronic viral hepatitis has emerged as one of the most common causes of disease and death worldwide. Because of their unique modes of replication and intimate association with the host immune system, hepatitis B virus (HBV) and hepatitis C virus (HCV) pose challenging problems to scientists in basic and applied research as well as to clinicians engaged in disease management. Although approved antiviral therapy is available for chronic HBV, the emergence of viral resistance provides a rationale for the development of novel chemotherapeutic agents. The lack of a robust cell culture system for HCV replication and a readily accessible small-animal model of HCV infection have hampered the development of antiviral agents for HCV. Neverthe-less, new antiviral agents targeting HCV are now in preclinical and clinical development.

This monograph, providing an up-to-date overview of the field of Hepatitis Prevention and Treatment, includes contributions from internationally recognized experts in the field of viral hepatitis, and covers the current state of knowledge and practice regarding the molecular biology, immunology, biochemistry, pharmacology and clinical aspects of chronic HBV and HCV infection. The volume includes salient topics such as: the history and epidemiology of HBV and HCV; recent insights into the molecular mechanisms of viral replication; the host immune response to infection and a discussion of the use (HBV) or potential development (HCV) of vaccines; the current standard of care for chronically-infected patients; and emerging therapies and issues associated with current antiviral treatments. The latest information to researchers and clinicians actively engaged in viral hepatitis research is provided, but also sufficient background and discussion of the literature to benefit the newcomer to the field.

Prevention and Treatment of Age-related Diseases

Автор: Rattan
Название: Prevention and Treatment of Age-related Diseases
ISBN: 9048172179 ISBN-13(EAN): 9789048172177
Издательство: Springer
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Цена: 26120.00 р.
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Описание: This book offers a broad-ranging assessment of current efforts of the molecular, cellular, hormonal, nutritional and lifestyle strategies being tested and applied by biogerontologists in the search for effective means of intervention, prevention and treatment of age-related diseases, and for achieving healthy old age.

Negotiating Pharmaceutical Uncertainty: Women`s Agency in a South African HIV Prevention Trial

Автор: Saethre Eirik, Stadler Jonathan
Название: Negotiating Pharmaceutical Uncertainty: Women`s Agency in a South African HIV Prevention Trial
ISBN: 0826521401 ISBN-13(EAN): 9780826521408
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 5821.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Telling the story of a clinical trial testing an innovative gel designed to prevent women from contracting HIV, Negotiating Pharmaceutical Uncertainty provides new insight into the complex and contradictory relationship between medical researchers and their subjects. Although clinical trials attempt to control and monitor participants' bodies, Saethre and Stadler argue that the inherent uncertainty of medical testing can create unanticipated opportunities for women to exercise control over their health, sexuality, and social relationships. Combining a critical analysis of the social production of biomedical knowledge and technologies with a detailed ethnography of the lives of female South African trial participants, this book brings to light issues of economic insecurity, racial disparities, and spiritual insecurities of Johannesburg's townships. Built on a series of tales ranging from strategy sessions at the National Institutes of Health to witchcraft accusations against the trial, Negotiating Pharmaceutical Uncertainty illuminates the everyday social lives of clinical trials.As embedded anthropologists, Saethre and Stadler provide a unique and nuanced perspective of the reality of a clinical trial that is often hidden from view.


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