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The Heterogeneity of Cancer Metabolism, Anne Le


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Автор: Anne Le
Название:  The Heterogeneity of Cancer Metabolism
ISBN: 9783030085254
Издательство: Springer
Классификация:


ISBN-10: 3030085252
Обложка/Формат: Soft cover
Страницы: 183
Вес: 0.31 кг.
Дата издания: 2018
Серия: Advances in Experimental Medicine and Biology
Язык: English
Издание: Softcover reprint of
Иллюстрации: 30 tables, color; 31 illustrations, color; xv, 183 p. 31 illus. in color.
Размер: Book (Paperback Initiative)
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Дополнительное описание: Part 1: The metabolism of cancer cells.- Chapter 1: Glucose Metabolism.- Chapter 2: Glutamine Metabolism.- Chapter 3: Amino Acid Metabolism.- Chapter 4: Lipid Metabolism.- Chapter 5: Epigenetics and oncometabolites.- Part 2: Heterogeneity of Cancer Metabo



Cancer Principles and Practice of Oncology: Handbook of Clinical Cancer Genetics

Автор: Matloff
Название: Cancer Principles and Practice of Oncology: Handbook of Clinical Cancer Genetics
ISBN: 1451190980 ISBN-13(EAN): 9781451190984
Издательство: Lippincott Williams & Wilkins
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Цена: 9608.00 р.
Наличие на складе: Поставка под заказ.

Описание: Genetic testing and counseling for cancer have made great strides in recent years. The popular demand for advanced screening, advances in testing, and the response of insurance companies and corporations have all served to shape this important area of cancer risk management. This practical, user-friendly guidebook allows you to search by disease site for the hereditary cancer syndromes relevant to your patient's cancer. This handy resource will help you formulate questions when expanding that patient's personal and family history, identify the genes that are most relevant, determine whether to refer that patient for genetic counseling and testing, and guide the patient’s long-term management based on the patient’s mutation-positive or –negative status. The guidebook will be of equal value to the practicing oncologist, surgeon, urologist, endocrinologist, gynecologist, primary care physician, physician's assistant, advanced practice nurse, and any other clinician counseling a patient who has had cancer. Look inside and discover… • Informative overview summarizes the history and current state of genetic cancer testing. • Site-specific chapters help you locate essential facts quickly. • Expert contributors share their years of experience in genetic testing and counseling. • Timely insights address key medical, ethical, legal, and financial implications of genetic cancer testing. Be sure your patients have the advance information they need… Pick up your copy today!

Metabolism in Cancer

Автор: Cramer
Название: Metabolism in Cancer
ISBN: 3319421166 ISBN-13(EAN): 9783319421162
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.

Real-Time Monitoring of Cancer Cell Metabolism for Drug Testing

Автор: Hamed Alborzinia
Название: Real-Time Monitoring of Cancer Cell Metabolism for Drug Testing
ISBN: 3658101601 ISBN-13(EAN): 9783658101602
Издательство: Springer
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Цена: 11179.00 р.
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Описание: Hamed Alborzinia uses the biosensor chip to monitor the metabolic and morphological changes in cancer cell lines in real time, particularly: (i) real-time measurements of basic cancer cell metabolism of different cancer cell lines;

Protein and Amino Acid Metabolism in Cancer Cachexia

Автор: Peter W.T. Pisters; Murray F. Brennan
Название: Protein and Amino Acid Metabolism in Cancer Cachexia
ISBN: 3662223481 ISBN-13(EAN): 9783662223482
Издательство: Springer
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Цена: 15672.00 р.
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Описание: Cancer cachexia is a complex syndrome characterized by diminished nutrient intake and progressive tissue depletion manifest clinically as anorexia and weight loss.

Cancer metabolism

Название: Cancer metabolism
ISBN: 1493990268 ISBN-13(EAN): 9781493990269
Издательство: Springer
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Цена: 30745.00 р.
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Описание: This volume details common experimental approaches in studies designed to illuminate various processes used to study cancer metabolism. Chapters are divided into three parts, the first part focuses on protocols commonly utilized in cancer metabolism studies, such as protocols comprising stable isotope labeling methods, protocols for studying glycolysis, gluconeogenesis and mitochondrial metabolism. The second part of the book describes methods used for generating hypotheses and identifying cancer markers, such as mass spectrometry- and NMR-based profiling tools. Last but not least, the third part is an overview of vital and actively researched topics in the field of cancer metabolism, as well as computational methodological approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Metabolism: Methods and Protocols aims to be an essential compilation of protocols utilized in many laboratories.

Stem Cells Heterogeneity in Cancer

Автор: Alexander Birbrair
Название: Stem Cells Heterogeneity in Cancer
ISBN: 3030143651 ISBN-13(EAN): 9783030143657
Издательство: Springer
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Цена: 22359.00 р.
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Описание:

This book presents a comprehensive discussion on the heterogeneity existing between different types of stem cells within the same tissue, for several types of cancers, e.g. glioblastoma stem cells. Recent developments have revealed completely different roles of distinct stem cells within the same organ.
Thus, Stem Cells Heterogeneity in Cancer provides a timely update us on the current information on stem cells heterogeneity in various tissues. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity – Novel Concepts, and Stem Cells Heterogeneity in Different Organs, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians.
Stem Cells Heterogeneity - Novel Concepts

Автор: Alexander Birbrair
Название: Stem Cells Heterogeneity - Novel Concepts
ISBN: 3030110958 ISBN-13(EAN): 9783030110956
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This book presents a comprehensive discussion on the novel concepts in stem cell heterogeneity, from pluripotent stem cells to human mesenchymal stem cells, adult and cancer stem cells of the thyroid, sarcoma, and more. Thus, Stem Cell Heterogeneity - Novel Concepts starts from a timely update on the current information on stem cells heterogeneity in various tissues and discusses new concepts and future directions. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity in Different Organs, and Stem Cells Heterogeneity in Cancer, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians.

Metabolism in Cancer

Автор: Thorsten Cramer; Clemens A. Schmitt
Название: Metabolism in Cancer
ISBN: 3319825011 ISBN-13(EAN): 9783319825014
Издательство: Springer
Рейтинг:
Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.


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