Metabolism in Cancer, Thorsten Cramer; Clemens A. Schmitt
Автор: John Werning Название: Oral Cancer ISBN: 3131358114 ISBN-13(EAN): 9783131358110 Издательство: Thieme Verlagsgruppe Рейтинг: Цена: 15029.00 р. 21470.00-30% Наличие на складе: Есть (1 шт.) Описание: Oral Cancer: Diagnosis, Management, and Rehabilitation provides readers with a systematic review of the diagnostic and treatment principles that maximize the outcomes of patients who have been diagnosed with oral cancer. Written by authorities in the fields of head and neck surgical oncology, radiation oncology, reconstructive surgery, dentistry, and oral and maxillofacial surgery, this textbook provides clinicians with a unified management philosophy that is firmly based upon the best available evidence in the peer-reviewed literature. In-depth clinical reviews of preferred treatment approaches and reconstructive techniques for each oral mucosal site facilitate the development of effective treatment strategies that are tailored to the location and extent of the lesion. The book describes the interrelationship between the site of oral cancer involvement and its impact on outcomes, such as local-regional cancer control and quality of life following treatment. Features:
Insightful reviews of controversial clinical issues, such as the management of early mandibular invasion and the clinically negative neck
Step-by-step descriptions of surgical techniques which improve access to particular regions of the oral cavity, permit the resection of tumors with minimal morbidity, and result in optimal reconstructive outcomes
Exhaustive coverage of topics that have heretofore received limited attention in textbooks devoted to oral cancer, including the evaluation and management of oral premalignant lesions, osseointegrated implantation and dental implant imaging, and orofacial pain
Educational photographs and illustrations highlighting important teaching points and critical nuances in surgical technique
Ideal for reading cover-to-cover, this book is both an indispensable reference for experienced clinicians and an essential educational tool for residents and other members of the multidisciplinary oral cancer team.
Автор: Pecorino Lauren Название: Molecular Biology of Cancer ISBN: 0198717342 ISBN-13(EAN): 9780198717348 Издательство: Oxford Academ Рейтинг: Цена: 7126.00 р. Наличие на складе: Поставка под заказ.
Описание: Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers the most engaging and accessible account of cancer biology that makes the link between our understanding of cancer and the development of new therapeutics crystal clear.
Автор: Vazquez, Alexei Название: Overflow Metabolism ISBN: 0128122080 ISBN-13(EAN): 9780128122082 Издательство: Elsevier Science Рейтинг: Цена: 12624.00 р. Наличие на складе: Нет в наличии.
Описание: Overflow Metabolism: From Yeast to Marathon Runners provides an overview of overflow metabolism, reviewing the major phenomenological aspects as observed in different organisms, followed by a critical analysis of proposed theories to explain overflow metabolism. In our ideal view of metabolism, we think of catabolism and anabolism. In catabolism nutrients break down to carbon dioxide and water to generate biochemical energy. In anabolism nutrients break down to generate building blocks for cell biosynthesis. Yet, when cells are pushed to high metabolic rates they exhibit incomplete catabolism of nutrients, with a lower energy yield and excretion of metabolic byproducts. . This phenomenon, characterized by the excretion of metabolic byproducts that could otherwise be used for catabolism or anabolism, is generally known as overflow metabolism. Overflow metabolism is a ubiquitous phenotype that has been conserved during evolution. Examples are the acetate switch in the bacterium E. coli, Crabtree effect in unicellular eukaryote yeasts, the lactate switch in sports medicine, and the Warburg effect in cancer. Several theories have been proposed to explain this seemingly wasteful phenotype. Yet, there is no consensus about what determines overflow metabolism and whether it offers any selective advantage.
Автор: Bence Название: Protein Tyrosine Phosphatase Control of Metabolism ISBN: 1461478545 ISBN-13(EAN): 9781461478546 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume highlights many aspects of PTP function in the context of metabolism. It covers the identification of new phosphatases that are involved in metabolic control and includes a review of tissue-specific effects of protein tyrosine phosphatase 1B.
Автор: Holmes Название: The Metabolism of Living Tissues ISBN: 1107494753 ISBN-13(EAN): 9781107494756 Издательство: Cambridge Academ Рейтинг: Цена: 3960.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Originally published in 1937, this book contains a general overview of `the dynamic side of biochemistry`, namely how cells process and produce energy. Holmes considers the metabolic activity of many different tissues, such as the liver and heart, as well as the role played by hormones and vitamins.
Автор: Jordan Lisa Название: Handbook of Iron Metabolism ISBN: 1632412381 ISBN-13(EAN): 9781632412386 Издательство: Неизвестно Цена: 16553.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Iron is an essential of human life. This book deals with various aspects related to iron metabolism. Iron has a variety of functions in the body, inclusive of the metabolism of oxygen in a range of biochemical activities. Iron, as heme or in its nonheme f
Автор: James M. Ntambi, Ph.D. Название: Stearoyl-CoA Desaturase Genes in Lipid Metabolism ISBN: 1493901532 ISBN-13(EAN): 9781493901531 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an overview of the growth of research on the role of the stearoyl-CoA desaturase (SCD) genes in metabolism in different species, including humans.
Описание: Genetic testing and counseling for cancer have made great strides in recent years. The popular demand for advanced screening, advances in testing, and the response of insurance companies and corporations have all served to shape this important area of cancer risk management. This practical, user-friendly guidebook allows you to search by disease site for the hereditary cancer syndromes relevant to your patient's cancer. This handy resource will help you formulate questions when expanding that patient's personal and family history, identify the genes that are most relevant, determine whether to refer that patient for genetic counseling and testing, and guide the patient’s long-term management based on the patient’s mutation-positive or –negative status. The guidebook will be of equal value to the practicing oncologist, surgeon, urologist, endocrinologist, gynecologist, primary care physician, physician's assistant, advanced practice nurse, and any other clinician counseling a patient who has had cancer. Look inside and discover… • Informative overview summarizes the history and current state of genetic cancer testing. • Site-specific chapters help you locate essential facts quickly. • Expert contributors share their years of experience in genetic testing and counseling. • Timely insights address key medical, ethical, legal, and financial implications of genetic cancer testing. Be sure your patients have the advance information they need… Pick up your copy today!
Автор: Cramer Название: Metabolism in Cancer ISBN: 3319421166 ISBN-13(EAN): 9783319421162 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.
Автор: Anne Le Название: The Heterogeneity of Cancer Metabolism ISBN: 3030085252 ISBN-13(EAN): 9783030085254 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Поставка под заказ.
Описание: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Автор: Peter W.T. Pisters; Murray F. Brennan Название: Protein and Amino Acid Metabolism in Cancer Cachexia ISBN: 3662223481 ISBN-13(EAN): 9783662223482 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cancer cachexia is a complex syndrome characterized by diminished nutrient intake and progressive tissue depletion manifest clinically as anorexia and weight loss.
Описание: Hamed Alborzinia uses the biosensor chip to monitor the metabolic and morphological changes in cancer cell lines in real time, particularly: (i) real-time measurements of basic cancer cell metabolism of different cancer cell lines;
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