Metabolism in Cancer, Thorsten Cramer; Clemens A. Schmitt
Автор: John Werning Название: Oral Cancer ISBN: 3131358114 ISBN-13(EAN): 9783131358110 Издательство: Thieme Verlagsgruppe Рейтинг: Цена: 15029.00 р. 21470.00-30% Наличие на складе: Есть (1 шт.) Описание: Oral Cancer: Diagnosis, Management, and Rehabilitation provides readers with a systematic review of the diagnostic and treatment principles that maximize the outcomes of patients who have been diagnosed with oral cancer. Written by authorities in the fields of head and neck surgical oncology, radiation oncology, reconstructive surgery, dentistry, and oral and maxillofacial surgery, this textbook provides clinicians with a unified management philosophy that is firmly based upon the best available evidence in the peer-reviewed literature. In-depth clinical reviews of preferred treatment approaches and reconstructive techniques for each oral mucosal site facilitate the development of effective treatment strategies that are tailored to the location and extent of the lesion. The book describes the interrelationship between the site of oral cancer involvement and its impact on outcomes, such as local-regional cancer control and quality of life following treatment. Features:
Insightful reviews of controversial clinical issues, such as the management of early mandibular invasion and the clinically negative neck
Step-by-step descriptions of surgical techniques which improve access to particular regions of the oral cavity, permit the resection of tumors with minimal morbidity, and result in optimal reconstructive outcomes
Exhaustive coverage of topics that have heretofore received limited attention in textbooks devoted to oral cancer, including the evaluation and management of oral premalignant lesions, osseointegrated implantation and dental implant imaging, and orofacial pain
Educational photographs and illustrations highlighting important teaching points and critical nuances in surgical technique
Ideal for reading cover-to-cover, this book is both an indispensable reference for experienced clinicians and an essential educational tool for residents and other members of the multidisciplinary oral cancer team.
Автор: Pecorino Lauren Название: Molecular Biology of Cancer ISBN: 0198717342 ISBN-13(EAN): 9780198717348 Издательство: Oxford Academ Рейтинг: Цена: 7126.00 р. Наличие на складе: Поставка под заказ.
Описание: Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers the most engaging and accessible account of cancer biology that makes the link between our understanding of cancer and the development of new therapeutics crystal clear.
Автор: Bence Название: Protein Tyrosine Phosphatase Control of Metabolism ISBN: 1461478545 ISBN-13(EAN): 9781461478546 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume highlights many aspects of PTP function in the context of metabolism. It covers the identification of new phosphatases that are involved in metabolic control and includes a review of tissue-specific effects of protein tyrosine phosphatase 1B.
Автор: James M. Ntambi, Ph.D. Название: Stearoyl-CoA Desaturase Genes in Lipid Metabolism ISBN: 1493901532 ISBN-13(EAN): 9781493901531 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an overview of the growth of research on the role of the stearoyl-CoA desaturase (SCD) genes in metabolism in different species, including humans.
Автор: Vazquez, Alexei Название: Overflow Metabolism ISBN: 0128122080 ISBN-13(EAN): 9780128122082 Издательство: Elsevier Science Рейтинг: Цена: 12624.00 р. Наличие на складе: Поставка под заказ.
Описание: Overflow Metabolism: From Yeast to Marathon Runners provides an overview of overflow metabolism, reviewing the major phenomenological aspects as observed in different organisms, followed by a critical analysis of proposed theories to explain overflow metabolism. In our ideal view of metabolism, we think of catabolism and anabolism. In catabolism nutrients break down to carbon dioxide and water to generate biochemical energy. In anabolism nutrients break down to generate building blocks for cell biosynthesis. Yet, when cells are pushed to high metabolic rates they exhibit incomplete catabolism of nutrients, with a lower energy yield and excretion of metabolic byproducts. . This phenomenon, characterized by the excretion of metabolic byproducts that could otherwise be used for catabolism or anabolism, is generally known as overflow metabolism. Overflow metabolism is a ubiquitous phenotype that has been conserved during evolution. Examples are the acetate switch in the bacterium E. coli, Crabtree effect in unicellular eukaryote yeasts, the lactate switch in sports medicine, and the Warburg effect in cancer. Several theories have been proposed to explain this seemingly wasteful phenotype. Yet, there is no consensus about what determines overflow metabolism and whether it offers any selective advantage.
Автор: Jordan Lisa Название: Handbook of Iron Metabolism ISBN: 1632412381 ISBN-13(EAN): 9781632412386 Издательство: Неизвестно Цена: 16553.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Iron is an essential of human life. This book deals with various aspects related to iron metabolism. Iron has a variety of functions in the body, inclusive of the metabolism of oxygen in a range of biochemical activities. Iron, as heme or in its nonheme f
Автор: Holmes Название: The Metabolism of Living Tissues ISBN: 1107494753 ISBN-13(EAN): 9781107494756 Издательство: Cambridge Academ Рейтинг: Цена: 3960.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Originally published in 1937, this book contains a general overview of `the dynamic side of biochemistry`, namely how cells process and produce energy. Holmes considers the metabolic activity of many different tissues, such as the liver and heart, as well as the role played by hormones and vitamins.
Автор: Cramer Название: Metabolism in Cancer ISBN: 3319421166 ISBN-13(EAN): 9783319421162 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.
Автор: Anne Le Название: The Heterogeneity of Cancer Metabolism ISBN: 3030085252 ISBN-13(EAN): 9783030085254 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Поставка под заказ.
Описание: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Автор: Peter W.T. Pisters; Murray F. Brennan Название: Protein and Amino Acid Metabolism in Cancer Cachexia ISBN: 3662223481 ISBN-13(EAN): 9783662223482 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cancer cachexia is a complex syndrome characterized by diminished nutrient intake and progressive tissue depletion manifest clinically as anorexia and weight loss.
Описание: Hamed Alborzinia uses the biosensor chip to monitor the metabolic and morphological changes in cancer cell lines in real time, particularly: (i) real-time measurements of basic cancer cell metabolism of different cancer cell lines;
Название: Cancer metabolism ISBN: 1493990268 ISBN-13(EAN): 9781493990269 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume details common experimental approaches in studies designed to illuminate various processes used to study cancer metabolism. Chapters are divided into three parts, the first part focuses on protocols commonly utilized in cancer metabolism studies, such as protocols comprising stable isotope labeling methods, protocols for studying glycolysis, gluconeogenesis and mitochondrial metabolism. The second part of the book describes methods used for generating hypotheses and identifying cancer markers, such as mass spectrometry- and NMR-based profiling tools. Last but not least, the third part is an overview of vital and actively researched topics in the field of cancer metabolism, as well as computational methodological approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Metabolism: Methods and Protocols aims to be an essential compilation of protocols utilized in many laboratories.
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