Antibacterials, Jed F. Fisher; Shahriar Mobashery; Marvin J. Mille
Автор: Jed Fisher; Shahriar Mobashery; Marvin Miller Название: Antibacterials ISBN: 3319708384 ISBN-13(EAN): 9783319708386 Издательство: Springer Рейтинг: Цена: 30745 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors
Автор: Jochen Kuhlmann; A. Dalhoff; H.-J. Zeiler Название: Quinolone Antibacterials ISBN: 3642803660 ISBN-13(EAN): 9783642803666 Издательство: Springer Рейтинг: Цена: 18167 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As this series deals predominantly with "experimental" characteristics of drugs, our volume is dedicated specifically to quinolones and emphasizes principally their preclinical and clinical phar- macological characteristics, despite the existence of several summaries on quinolones.
Описание: Offers many antibiotics and antimicrobial compounds: in development, experimental, and in use. This title covers chemistry and synthesis, classification, structure-activity relationships, mechanisms of action and resistance, breakpoints, in vitro/in vivo activities, epidemiology, pharmacokinetics, metabolism, and adverse events.
Автор: Joyce Sutcliffe; Nafsika Georgopapadakou Название: Emerging Targets in Antibacterial and Antifungal Chemotherapy ISBN: 146136440X ISBN-13(EAN): 9781461364405 Издательство: Springer Рейтинг: Цена: 30039 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Emerging Targets in Antibacterial and Antifungal Chemotherapy offers constructive ideas to researchers that could lead to the discovery of entirely new classes of drugs.
Автор: Elena Ivanova; Russell Crawford Название: Antibacterial Surfaces ISBN: 3319360000 ISBN-13(EAN): 9783319360003 Издательство: Springer Рейтинг: Цена: 15672 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
'Antibacterial Surfaces' reports the advances being made in the design of antibacterial surfaces, which have the ability to either prevent the initial attachment of bacterial cells, or kill any cells that do come into contact.
This book discusses the mechanisms associated with the attachment of bacteria to surfaces and the main strategies currently being employed to control the initial attachment processes. These strategies are expanded upon in the subsequent chapters, where the definition and description of antibacterial surfaces are clarified, as are the mechanisms that come into play when determining the effectiveness of an antibacterial surface.
Subsequent chapters discuss a number of naturally occurring antibacterial surfaces, the methods currently being used for producing synthetic antibacterial surfaces, and the current and potential applications of such materials.
This book will be of great interest to people who work with materials that need to remain free of bacterial films, from designing safer biomedical implants to the production of self-cleaning materials where the prevention of biofilm formation has significant economic advantages.
Автор: Jed F. Fisher; Shahriar Mobashery; Marvin J. Mille Название: Antibacterials ISBN: 3030099962 ISBN-13(EAN): 9783030099961 Издательство: Springer Рейтинг: Цена: 32142 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors
Описание: Enterococcus faecalis is a gram-positive, coccus shaped, lactic acid bacterium, with demonstrated ubiquity across multiple anatomical sites. Enterococcus faecalis isolates have been isolated from clinical samples as the etiological agent in patients with overt infections, and from body sites previously thought to be sterile but absent of signs and symptoms of infection. E. faecalis is implicated in both human health and disease, recognised as a commensal, a probiotic and an opportunistic multiply resistant pathogen. E faecalis has emerged as a key pathogen in nosocomial infections. Enterococcus faecalis is a commensal bacterium inhabiting the gastro-intestinal tract of humans. Interestingly, although it is not clear whether E faecalis is part of the oral cavity microbiome, it is frequently recovered from root canal infections. Specifically, it is the major pathogen found in persistent infections associated with root canal treatment failure. Moreover, E faecalis is one of the leading multidrug resistant nosocomial pathogens, causing infective endocarditis, and participating in urinary tract, wound, and device- device-related infections. This book discusses the molecular characteristics, its role in nonsocomial infections and the antibacterial effects of Enterococcus faecalis. It begins by discussing the virulence factors of enterococcus faecalis and concludes with E faecalis in dental infections.
Автор: William Shafer Название: Antibacterial Peptide Protocols ISBN: 1617370274 ISBN-13(EAN): 9781617370274 Издательство: Springer Рейтинг: Цена: 20263 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Antibacterial Peptide Protocols, will attest, my enthusi- asm for the field of antibacterial peptides is based on a conviction (and I am unashamed to say, prejudice) that these substances are in essence antibiotics produced by the host that then participate in host defense against infectious agents.
Автор: S.L. Dax Название: Antibacterial Chemotherapeutic Agents ISBN: 9401065314 ISBN-13(EAN): 9789401065313 Издательство: Springer Рейтинг: Цена: 28732 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Over the past 50 years a wide variety of antibacterial substances have been discovered and synthesised, and their use in treating bacterial infection has been spectacularly successful.
Описание: Examines various aspects of antibacterial drugs - from basic concepts to complex therapeutic mechanisms of polymer systems, including an extensive overview of antibacterial drugs. The book provides the reader with insights into the development and history of antibacterial drugs.
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