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Bacterial Multidrug Exporters, Akihito Yamaguchi; Kunihiko Nishino


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Автор: Akihito Yamaguchi; Kunihiko Nishino
Название:  Bacterial Multidrug Exporters
ISBN: 9781493984909
Издательство: Springer
Классификация:
ISBN-10: 149398490X
Обложка/Формат: Soft cover
Страницы: 355
Вес: 0.70 кг.
Дата издания: 2018
Серия: Methods in Molecular Biology
Язык: English
Издание: Softcover reprint of
Иллюстрации: 53 illustrations, color; 38 illustrations, black and white; xii, 355 p. 91 illus., 53 illus. in color.
Размер: Book (Paperback Initiative)
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This detailed volume utilizes our current understanding of the structural basis of multidrug recognition and multidrug efflux mechanisms to provide protocols involving these vital intrinsic membrane proteins widely distributed in bacteria. Beginning with protocols for the structural analysis of bacterial multidrug exporters, the book continues with sections on biochemical and bioengineering analysis, computational analysis, biomedical approaches, as well as advanced technologies expected to be applied to multidrug efflux transport studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective chapters, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Bacterial Multidrug Exporters: Methods and Protocols serves as an ideal guide to this fast moving field of study.
Дополнительное описание: High Resolution Crystallographic Analysis of AcrB Using Designed Ankyrin Repeat Proteins (DARPins).- Crystallographic Analysis of Drug and Inhibitor-Binding Structure of RND-Type Multidrug Exporter AcrB in Physiologically-Relevant Asymmetric Crystals.- Cr



Bacterial Multidrug Exporters

Автор: Akihito Yamaguchi; Kunihiko Nishino
Название: Bacterial Multidrug Exporters
ISBN: 1493974521 ISBN-13(EAN): 9781493974528
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This detailed volume utilizes our current understanding of the structural basis of multidrug recognition and multidrug efflux mechanisms to provide protocols involving these vital intrinsic membrane proteins widely distributed in bacteria.

Combination Therapy Against Multidrug Resistance

Автор: Wani, Mohmmad Younus
Название: Combination Therapy Against Multidrug Resistance
ISBN: 0128205768 ISBN-13(EAN): 9780128205761
Издательство: Elsevier Science
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Цена: 19875.00 р.
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Описание:

Combination Therapy against Multidrug Resistance explores the potential of combination therapy as an efficient strategy to combat multi-drug resistance. Multidrug resistance (MDR) occurs when microorganisms such as bacteria, fungi, viruses, and parasites are excessively exposed to antimicrobial drugs such as antibiotics, antifungals, or antivirals, and in response the microorganism undergoes mutations or develops different resistance mechanisms to combat the drug for its survival. MDR is becoming an increasingly serious problem in both developed and developing nations. Bacterial resistance to antibiotics has developed faster than the production of new antibiotics, making bacterial infections increasingly difficult to treat, and the same is true for a variety of other diseases. Combination therapy proves to be a promising strategy as it offers potential benefits such as a broad spectrum of efficacy, greater potency than the drugs used in monotherapy, improved safety and tolerability, and reduction in the number of resistant organisms. This book considers how combination therapy can be applied in multiple situations, including cancer, HIV, tuberculosis, fungal infections, and more. Combination Therapy Against Multidrug Resistance gathers the most relevant information on the prospects of combination therapy as a strategy to combat multridrug resistance and helping to motivate the industrial sector and government agencies to invest more in research and development of this strategy as a weapon to tackle the multidrug resistance problem. It will be useful to academics and researchers involved in the development of new antimicrobial or antiinfective agents and treatment strtategies to combat multidrug resistance. Clinicians and medical nurses working in the field of infection prevention and control (IPC) will also find the book relevant

Protein Secretion and Export in Bacteria

Автор: Henry C. Wu; Phang C. Tai
Название: Protein Secretion and Export in Bacteria
ISBN: 3642712533 ISBN-13(EAN): 9783642712531
Издательство: Springer
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Цена: 18167.00 р.
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