Combination Therapy Against Multidrug Resistance, Wani, Mohmmad Younus
Автор: Maciej Banach Название: Combination Therapy In Dyslipidemia ISBN: 3319367218 ISBN-13(EAN): 9783319367217 Издательство: Springer Рейтинг: Цена: 12577.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Comprising contributions from leading lipidologists from around the world, this book presents the latest and most comprehensive knowledge on the different options for combination therapy of dyslipidemia and includes discussion of future therapies that are currently in late stages of clinical evaluation.
Автор: Erik De Clercq; Anne-Mieke Vandamme Название: Combination Therapy of AIDS ISBN: 3034896042 ISBN-13(EAN): 9783034896047 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An extensive assessment of combination therapy of AIDS. Main focus is put on the Highly Active Antiretroviral Therapy (HAART) but other therapies like salvage therapy are also discussed. The chapters cover efficacy, treatment, causes of treatment failure, clinical care, guidelines, pharmacology.
Автор: Maciej Banach Название: Combination Therapy In Dyslipidemia ISBN: 3319204327 ISBN-13(EAN): 9783319204321 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Comprising contributions from leading lipidologists from around the world, this book presents the latest and most comprehensive knowledge on the different options for combination therapy of dyslipidemia and includes discussion of future therapies that are currently in late stages of clinical evaluation. Dyslipidemia is a leading cause of cardiovascular morbidity and mortality and most patients with this condition fail to achieve adequate control of their serum lipid levels with monotherapy. However, recent US and European guideline recommendations, based on randomized, controlled trials, fail to discuss combination therapy options for patients with dyslipidemia.Statins remain the mainstay of drug therapy for hyperlipidemia and chapters in this book specifically examine the role of add-on therapy with different agents modulating the different lipid fractions in the blood, e.g. bile acid sequestrants, fibric acid derivatives (fibrates), omega-3 fatty acids (fish oils), inhibitors of Niemann-Pick C1 like 1 (NPC1L1) protein, cholesteryl ester transfer protein (CETP), apolipoprotein B-100 and microsomal triglyceride transfer protein (MTP) and the emerging proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. There is additional discussion of the role of non-drug therapy options such as nutraceuticals, functional foods and lipoprotein apheresis. The book also discusses the combination of antihypertensive drugs with lipid-lowering drugs in the management of cardiovascular risk in patents with dyslipidemia.
Автор: Neutel Название: Combination Therapy in Hypertension ISBN: 1908517255 ISBN-13(EAN): 9781908517258 Издательство: Springer Рейтинг: Цена: 6008.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book addresses combined therapies for managing and treating hypertension, discusses benefits of monotherapy and combination therapy, examines risk of adverse effects, compliance and cost of the available therapies. Reviews relevant outcome studies.
Автор: Harrison Название: Combination Treatment in Autoimmune Disseases ISBN: 3540430369 ISBN-13(EAN): 9783540430360 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book consists of contributions from the most prominent experts in this field. In the first section the general principles of combination treatment are discussed, from rationale and methodology to benefits of risks in daily practice. The second section concerns specific diseases. It is striking that although there is so much experience with combining DMARDS in RA, for several other autoimmune diseases combination therapy has not yet been developed. Denton and Black, on the other hand, are able to add a refreshing new meaning to the term "combination therapy" in systemic sclerosis by pointing out the aetiologies beyond those caused by immunopathology, and dealing with combinations of therapy to address issues beyond immunotherapy. The last section is devoted to the future, and the editors hope to come back in 2010 with an issue which will look back and determine whether the predictions of Brooks, Moore, Huizinga and Breedveld have come true.
Описание: This type of resistance, known as multidrug or pleiotropic drug resistance, is characterized by cross-resistance of cells to several different classes of cytotoxic drugs, including some of the most commonly used anticancer agents.
Автор: Akihito Yamaguchi; Kunihiko Nishino Название: Bacterial Multidrug Exporters ISBN: 1493974521 ISBN-13(EAN): 9781493974528 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed volume utilizes our current understanding of the structural basis of multidrug recognition and multidrug efflux mechanisms to provide protocols involving these vital intrinsic membrane proteins widely distributed in bacteria.
Автор: Akihito Yamaguchi; Kunihiko Nishino Название: Bacterial Multidrug Exporters ISBN: 149398490X ISBN-13(EAN): 9781493984909 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Поставка под заказ.
Описание: This detailed volume utilizes our current understanding of the structural basis of multidrug recognition and multidrug efflux mechanisms to provide protocols involving these vital intrinsic membrane proteins widely distributed in bacteria. Beginning with protocols for the structural analysis of bacterial multidrug exporters, the book continues with sections on biochemical and bioengineering analysis, computational analysis, biomedical approaches, as well as advanced technologies expected to be applied to multidrug efflux transport studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective chapters, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Bacterial Multidrug Exporters: Methods and Protocols serves as an ideal guide to this fast moving field of study.
Автор: W.B. Harrison; B.A.C. Dijkmans Название: Combination Treatment in Autoimmune Diseases ISBN: 3642077048 ISBN-13(EAN): 9783642077043 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Despite the advance of instituting monotherapy with a single optimised disease-modifying anti-rheumatic drug (DMARD) - with methotrexate as prototype agent in RA - adequate disease re- mission is not often achieved, and adverse events may well prevent the use of higher dosages of the single agent in question.
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