Описание: Rarely have the many mechanisms that might underlie neural plasticity been examined as explicitly as they are in this broad, lavishly illustrated treatment of plasticity in the somatosensory system.
Автор: Ballanyi Название: Isolated Central Nervous System Circuits ISBN: 1627030190 ISBN-13(EAN): 9781627030199 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Advances in methodologies and experimental models are pivotal to furthering our understanding of central nervous system (CNS) functions in mammals. Isolated Central Nervous System Circuits examines the application a variety of technologies to mostly active in vitro preparations from basically different CNS regions with a diversity of functions. From patch-clamp, multiphoton imaging, live fluorescent protein expression, or immunohistochemistry techniques to acute or 'organotypic' slices and en bloc preparations, this detailed volume features key protocols and examples for exciting results from the labs of renowned experts. Written for the popular Neuromethods series, chapters include the kind of thorough implementation advice that is vital for achieving successful results. Comprehensive and cutting-edge, Isolated Central Nervous System Circuits will greatly aid scientists to further improve models and to develop corresponding models of not yet intensively studied structures such as nucleus ruber, superior colliculus, or basal ganglia.
Автор: Bruno P. Guiard; Giuseppe Di Giovanni Название: 5-HT2A Receptors in the Central Nervous System ISBN: 3319704729 ISBN-13(EAN): 9783319704722 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 5-HT2A receptors are G-protein coupled receptors that are widely distributed throughout the brain, most notably on neuronal and glial cells. 5-HT2A receptors have been implicated in various central physiological functions including mood regulation, memory, sleep, nociception, eating, and reward behaviors, and they are also believed to control the cardiovascular system. This book provides a comprehensive overview of these receptors including sections on their properties and distribution, approaches for their study, their role in a number of brain functions and diseases, and their role as therapeutic targets. ?
Nanomedicine in Central Nervous System Injury and Repair (IRN), Volume 137, the latest release in the International Review of Neurobiology series presents comprehensive chapters that cover a broad range of topics, including, but not limited to, how Diabetes exacerbates methamphetamine induced blood-brain barrier breakdown, edema formation, oxidative stress and myelin damage, and how Focal blast brain injury induces rapid edema formation, blood-brain barrier breakdown and intensive cellular damage. In addition, the Neuroprotective effects of a multimodal drug cerebrolysin are explored, as is how Nanowired cerebrolysin potentiates neuroprotective effects of histamine H3 receptor inverse agonist and antagonist with partial H4 agonist in Alzheimer's Disease.
This series reviews current knowledge and understanding on how to repair the damaged spinal cord and brain with nanomedicine, detailing new therapeutic advances and providing a starting point for researchers and practitioners entering the field.
Provides cutting-edge research on the damaged spinal cord and brain
Presents new therapeutic advances
Reviews current knowledge and understanding
Автор: Firas H. Kobeissy et al Название: Injury Models of the Central Nervous System ISBN: 1493938142 ISBN-13(EAN): 9781493938148 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume discusses experimental brain injury models thatcontain valuable information carefully chosen to widen the researchers’ horizonabout neurotrauma. Injury Models of Central Nervous System: Methods and Protocols contains relevant experimental design approaches that have beenadapted and made ready for application in laboratory settings. For easiernavigation, the chapters are categorized into 6 parts: Introduction, GeneralConsideration in Using Animal Laboratory in CNS Injury Research, Classical TBIModels and Their Link with Pathophysiological Features of CBS Injury – Models,Special Topics in CNS Trauma: Comorbid Conditions in CNS Injury, OutcomeMeasures in Brain Injury Models, and Future Directions. Written in the highly successful Methods inMolecular Biology series format, chapters include introductions to theirrespective topics, lists of the necessary materials and reagents, step-by-step,readily reproducible laboratory protocols, and tips on troubleshooting andavoiding known pitfalls.Practical and thorough, Injury Models of Central Nervous Systems: Methods and Protocols, is a very useful reference towards theprogress of this discipline.
Автор: Abel Lajtha Название: Receptors in the Nervous System ISBN: 1468445707 ISBN-13(EAN): 9781468445701 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A major advance in the biological sciences in the past decade has been the biochemical identification of cell membrane receptors. It was only in the early 1970s that methods for the specific measurement, chemical characterization, and physical isolation of cell membrane receptors were developed.
Автор: Ian S. Zagon; Patricia J. McLaughlin Название: Receptors in the Developing Nervous System ISBN: 9401046743 ISBN-13(EAN): 9789401046749 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Receptors for cell hormones, growth factors, Fourth, alterations in the development of neu- and neurotransmitters are involved in the ral receptors may have profound implications control and modulation of an enormous array for the structure and function of the of biological processes.
Автор: Zagon; McLaughlin Название: Receptors in the Developing Nervous System ISBN: 9401046727 ISBN-13(EAN): 9789401046725 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Receptors for cell hormones, growth factors, Fourth, alterations in the development of and neurotransmitters are involved in the neural receptors may have profound implica- control and modulation of an enormous array tions for the structure and function of the of biological processes.
Автор: Dwaine F. Emerich; Reginald L. Dean III; Paul R. S Название: Central Nervous System Diseases ISBN: 089603724X ISBN-13(EAN): 9780896037243 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A critical review of the animal models used in developing powerful new therapies for central nervous system diseases. Techniques that rely heavily on behavioural analyses, as well as models developed from infusions of neurotoxins and from advances in molecular biology, are thoroughly explicated.
Автор: Kewal K. Jain Название: Drug Delivery to the Central Nervous System ISBN: 1493961594 ISBN-13(EAN): 9781493961597 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In addition to those methods, several overviews of innovative methods and their applications are presented in order to give a glimpse of the future of this research. As a volume in the successful Neuromethods series, this book presents its protocols with the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Drug Delivery to the Central Nervous System serves as an ideal guide to scientists continuing to pursue knowledge of the delicate interactions between pharmaceuticals and the brain.
Автор: Dwaine F. Emerich; Reginald L. Dean III; Paul R. S Название: Central Nervous System Diseases ISBN: 1617371521 ISBN-13(EAN): 9781617371523 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Prominent experimentalists critically review the animal models widely used in developing powerful new therapies for central nervous system diseases.
Автор: Francesco Clementi; Cecilia Gotti; Emanuele Sher Название: Nicotinic Acetylcholine Receptors in the Nervous System ISBN: 364274169X ISBN-13(EAN): 9783642741692 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop on Nicotine Acetylcholine Receptors in the Nervous System held in Venice, Italy, April 18-21, 1988
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