Targeting Protein-Protein Interactions by Small Molecules, Chunquan Sheng; Gunda I. Georg

Автор: Sheng
Название: Targeting Protein-Protein Interactions by Small Molecules
ISBN: 9811307725 ISBN-13(EAN): 9789811307720
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies of small molecule PPI inhibitors. The first part discusses various discovery strategies for small molecule PPI inhibitors, such as high throughput screening, hot spot-based design, computational approaches, and fragment-based design. The second part presents recent advances in small molecule inhibitors, focusing on clinical candidates and new PPI targets. This book has broad appeal and is of significant interest to the pharmaceutical science and medicinal chemistry communities.

Автор: Herbert Waldmann; Marcus Koppitz
Название: Small Molecule — Protein Interactions
ISBN: 3662053160 ISBN-13(EAN): 9783662053164
Издательство: Springer
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Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Based on the international workshop on `Small Molecule - Protein Interactions` held in Berlin, April 24-26, 2002, researchers from industry and academic laboratories describe novel and efficient ways selecting promising new drug targets and developing small molecule inhibitors against them.