Описание: Describing the use of biophysical and biochemical methods to prove that calcium has a positive feedback effect on amplifying and sustaining CD3 phosphorylation and should enhance T-cell sensitivity to foreign antigens, this thesis couples the use of nuclear magnetic resonance (NMR) to the analysis of signaling phenomena in living cells.
Автор: Sudhir Gupta; Thomas Waldmann Название: Mechanisms of Lymphocyte Activation and Immune Regulation IV ISBN: 1461365007 ISBN-13(EAN): 9781461365006 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent data suggest a role of interaction between plasma membrane molecules of activated T helper cells and B cells, B cells primed with plasma membrane of activated T helper cells and cytokines, and interaction between bone marrow stromal cells and B cell progenitors and precursors, in the B cell development, proliferation, and differentiation.
Автор: Sudhir Gupta; Alan Sher; Rafi Ahmed Название: Mechanisms of Lymphocyte Activation and Immune Regulation VII ISBN: 146137443X ISBN-13(EAN): 9781461374435 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Seventh International Conference held in New Port Beach, California, February 6-8, 1998
Автор: Sudhir Gupta; Eugene Butcher; William E. Paul Название: Lymphocyte Activation and Immune Regulation IX ISBN: 1461352266 ISBN-13(EAN): 9781461352266 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Ninth International Conference on Lymphocyte Activation and Immune Regulation held on February 8-10, 2002 in Newport Beach, California, U.S.A
Описание: Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases.
Автор: Sudhir Gupta; William E. Paul; Ralph Steinman Название: Mechanisms of Lymphocyte Activation and Immune Regulation X ISBN: 1441937005 ISBN-13(EAN): 9781441937001 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is edited by Dr. Sudhir Gupta, internationally recognized expert in Immunology, Professor of Medicine, Pathology, Microbiology and Molecular Genetics. Topics include toll receptors, dendritic cells, NK cells, and complement receptors.
Автор: Sudhir Gupta; William E. Paul; Max D. Cooper; Elle Название: Mechanisms of Lymphocyte Activation and Immune Regulation III ISBN: 1468459457 ISBN-13(EAN): 9781468459456 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Third International Conference on Lymphocyte Activation and Immune Regulation, held in Newport Beach, California, February 16--18, 1990
Автор: Sudhir Gupta; William E. Paul; Anthony DeFranco; R Название: Mechanisms of Lymphocyte Activation and Immune Regulation V ISBN: 0306448971 ISBN-13(EAN): 9780306448973 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It includes a contemporary assessment of B cell antigen receptor structures, and discussion of the role of Ig-a/lg-B polypeptides in linking the antigen receptor to intracellular signal transduction pathways.
Автор: Sudhir Gupta; J. John Cohen Название: Mechanisms of Lymphocyte Activation and Immune Regulation VI ISBN: 1489902767 ISBN-13(EAN): 9781489902764 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Since programmed cell death was first described in insects in 1964 and apoptosis was described in 1972, rapid progress has been made in understanding the basic mechanisms and genes regulating programmed cell death and apoptosis. In addition, defects in various genes regulating programmed cell death have been delineated in several experimental models of human diseases. This volume surveys various aspects of these rapidly developing areas of research in programmed cell death/apoptosis. This volume should be of interest to basic immunologists and molecular biologists. The volume begins with a historical perspective of cell death. The remainder of the volume is divided into four different parts. Part I deals with the signaling pathways in apoptosis, including cell cycle control of apoptosis, role of ceramide in apoptosis, role of antibody signaling, and biochemical regulation of apoptosis. The mechanisms for recognition of apoptotic lymphocytes by macrophages are also reviewed. Part II examines the role of various genes that regulate apoptosis, including the role ofFas, FasL, and other TNF family members in apoptosis and homeostatic regulation of immune response. Recently described splice variants and their influence on apoptosis are also reviewed, and the role of the members of the Bcl-2 family in apoptosis is discussed in detail. Part III reviews various aspects of apoptosis in B lymphocytes, including mechanisms that regulate apoptosis/survival of B lymphocytes and the regulation of Fas-mediated apoptosis in B lymphocytes.
Автор: Sudhir Gupta; J. John Cohen Название: Mechanisms of Lymphocyte Activation and Immune Regulation VI ISBN: 0306454831 ISBN-13(EAN): 9780306454837 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Sixth International Conference held in Newport Beach, California, Feb 2-4, 1996
Описание: It includes a model for the T cell receptor interaction with a complex of MHC plus antigen, structure of y c`i T cell receptor and their distinct isotypic forms, the role of zeta chain in the expression and structure of T cell receptors and its role in transmembrane signalling.
Автор: Sudhir Gupta; Frederick W. Alt; Max D. Cooper; Fri Название: Mechanisms of Lymphocyte Activation and Immune Regulation XI ISBN: 1441942831 ISBN-13(EAN): 9781441942838 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In recent years, major developments have increased understanding of various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires.
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