Mechanisms of Lymphocyte Activation and Immune Regulation XI, Sudhir Gupta; Frederick W. Alt; Max D. Cooper; Fri

Автор: Stenmark Harald
Название: Phosphoinositides in Subcellular Targeting and Enzyme Activation
ISBN: 3540009507 ISBN-13(EAN): 9783540009504
Издательство: Springer
Рейтинг:
Цена: 1092.00 р.
Наличие на складе: Есть (3 шт.)
Описание: Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.

Автор: Rast
Название: Immune Receptors
ISBN: 1617791385 ISBN-13(EAN): 9781617791383
Издательство: Springer
Рейтинг:
Цена: 20263.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Immunology has made significant progress in the past decade, driven forward by rapidly advancing technology and a renewed interest in the vast realm of innate immunity. The receptors that mediate these functions are at the front lines of both protective and regulative roles of the immune system.  In Immune Receptors: Methods and Protocols, expert researchers present a variety of experimental approaches to the characterization of immune receptors and the cell biology that mediates their functions.  These include imaging techniques that aim to understand receptor localization and trafficking, techniques to measure receptor-ligand interactions, strategies to identify novel ligands and methods to analyze downstream receptor signaling, as well as strategies for genomic and proteomic characterization of receptor repertoires. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Immune Receptors: Methods and Protocols offers technical descriptions and protocols that will be useful both to investigators who are interested in carrying out these procedures and to those who seek a deeper understanding of the bench science that lies behind the immunology literature.

Автор: Cornelis Murre
Название: Epigenetic Regulation of Lymphocyte Development
ISBN: 3642447678 ISBN-13(EAN): 9783642447679
Издательство: Springer
Рейтинг:
Цена: 32004.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.

Автор: Constantine Tsoukas
Название: Lymphocyte Signal Transduction
ISBN: 1489990135 ISBN-13(EAN): 9781489990136
Издательство: Springer
Рейтинг:
Цена: 34937.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Signal transduction through leukocyte receptors involves a variety of signaling molecules including kinases, phosphatases, adaptor proteins, small GTPases GTP exchange factors, membrane phospholipids as well as others. These signal transducers, regulated by inter- and intra-molecular interactions, as well as by various post-translational modifications, lead to the activation of transcription factors that mediate cellular differentiation and growth, effector cell functions, and apoptotic cell death. Several investigators from various parts of the world convened at the 3rd Lymphocyte Signal Transduction Workshop in Crete, Greece from May 27 to June 1, 2005 to discuss their most recent findings in leukocyte signaling. This volume represents a collection of topics discussed during the conference.