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Structure and Function of GPCRs, Guillaume Lebon


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Цена: 30745.00р.
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При оформлении заказа до: 2025-07-28
Ориентировочная дата поставки: Август-начало Сентября
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Автор: Guillaume Lebon
Название:  Structure and Function of GPCRs
ISBN: 9783030245894
Издательство: Springer
Классификация:




ISBN-10: 3030245896
Обложка/Формат: Hardcover
Страницы: 289
Вес: 0.62 кг.
Дата издания: 2019
Серия: Topics in Medicinal Chemistry
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 52 illustrations, color; 19 illustrations, black and white; xiv, 289 p. 71 illus., 52 illus. in color.
Размер: 234 x 156 x 18
Читательская аудитория: Professional & vocational
Основная тема: Chemistry
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:
This book introduces readers to the latest advances in G protein-coupled receptor (GPCR) biology. It reviews our current understanding of the structural basis of ligand binding and allosteric mechanisms, following a decade of technological breakthroughs. Several examples of structure-based drug discovery are presented, together with the future challenges involved in designing better drugs that target GPCRs. In turn, the book illustrates the important concept of GPCR biased signaling in physiological contexts, and presents fluorescent- and light-based methodologies frequently used to measure GPCR signaling or to trace their dynamics in cells upon ligand activation.
Taken together, the chapters provide an essential overview and toolkit for new scientific investigators who plan to develop GPCR projects. All chapters were written by experts in their respective fields, and share valuable insights and powerful methodologies for the GPCR field.

Дополнительное описание: Structures of Non-rhodopsin GPCRs Elucidated Through X-Ray Crystallography.- NMR Spectroscopy for the Characterization of GPCR Energy Landscapes.- Structure and Activation Mechanism of GPCRs.- Structure-Based Discovery of GPCR Ligands from Crystal Structu



GPCRs: From Deorphanization to Lead Structure Identification

Автор: Bourne
Название: GPCRs: From Deorphanization to Lead Structure Identification
ISBN: 3642080316 ISBN-13(EAN): 9783642080319
Издательство: Springer
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Цена: 19589.00 р.
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Описание: This book offers an insight into the approaches taken by industry and academia to address GPCRs and depict how mature this target class-oriented research has become in the last decade. Coverage also reflects the actual trends in the fast-emerging field of GPCR research in academia and industry.

Proteins: Structure and Function

Автор: David Whitford
Название: Proteins: Structure and Function
ISBN: 0471498947 ISBN-13(EAN): 9780471498940
Издательство: Wiley
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Цена: 8546.00 р.
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Описание: * An accessible introduction to the principles of protein structure and function. * Beautifully illustrated throughout in full colour. * Includes end of chapter problems, references to further reading and a full glossary of terms. * Associated website including web-based tutorials, problems and additional content. .

Chemistry of Structure-Function Relationships in Cheese

Автор: Edyth L. Malin; Michael H. Tunick
Название: Chemistry of Structure-Function Relationships in Cheese
ISBN: 1461357829 ISBN-13(EAN): 9781461357827
Издательство: Springer
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Цена: 15672.00 р.
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Описание: The ability to accelerate traditional ripening procedures has altered the production of certain cheeses, and the emphasis on decreasing the intake of dietary fat, especially in the United States, has prompted the development of technology for producing low-fat cheeses with traditional texture and flavor.

Modelling of GPCRs

Автор: Andrea Strasser; Hans-Joachim Wittmann
Название: Modelling of GPCRs
ISBN: 9401780919 ISBN-13(EAN): 9789401780919
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This practical introduction to molecular modelling of GPCRs covers core principles, and moves on to present advanced GPCR modelling techniques. Includes data on crystal structures and essential amino acid sequences, as well as LINUX commands and examples.

Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases

Автор: Senthilkumar Rajagopal; Murugavel Ponnusamy
Название: Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases
ISBN: 9811315701 ISBN-13(EAN): 9789811315701
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This book will provide current understandings about two ubiquitously expressed metabotropic GPCRs, G-coupled purinoreceptor type 2 (P2Y) and Takeda G-protein-coupled bile acid receptor 5 (TGR5). G protein coupled receptors (GPCRs) are the largest family of proteins implicated in majority of cellular responses. The two receptor sub-families play a central role in many physiological functions as well as in many pathological conditions. This book offers up-to-date information on the physiological functions, signaling pathways and regulatory mechanisms of P2Y and TGR5 receptors. In addition, this book provides a comprehensive overview about the abnormalities of P2Y/TGR5 receptors and their contribution in the development and progression of pathological conditions. It also covers the currently available natural, chemical and pharmacological agents targeting these two receptor families and their therapeutic implications in P2Y and TGR5 associated disorders. This book is a valuable source for beginners and researchers to follow the rapidly progressing field of these two GPCR subfamily members.

GPCR Signalling Complexes – Synthesis, Assembly, Trafficking and Specificity

Автор: Denis J. Dupr?; Terence E. H?bert; Ralf Jockers
Название: GPCR Signalling Complexes – Synthesis, Assembly, Trafficking and Specificity
ISBN: 9401780994 ISBN-13(EAN): 9789401780995
Издательство: Springer
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Цена: 22201.00 р.
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Описание: Main Question: G protein coupled receptors are involved in highly efficient and specific activation of signalling pathways. How do GPCR signalling complexes get assembled to generate such specificity? Then, we need to understand how each partner of the signalling complex is selected to join a complex, and what makes this assembly possible.

Structure-function analysis of edible fats

Автор: Alejandro G. Marangoni
Название: Structure-function analysis of edible fats
ISBN: 0128140410 ISBN-13(EAN): 9780128140413
Издательство: Elsevier Science
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Цена: 16161.00 р.
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Описание:

Structure-Function Analysis of Edible Fats, Second Edition summarizes the latest approaches in the quantification of the physical structure of fats and its relationship to macroscopic functionality. The book takes a proven, general approach, presenting principles and techniques in a way that can be applied to any lipidic material. As the maturity of the field has increased since the first edition, there is an increased need for more sophisticated quantitative approaches to common problems encountered by industry. This book outlines modern methods used for this purpose by some of the leading authorities in the field today.

Edited by expert Alejandro Marangoni, and with contributions from leaders in field, the book features the latest developments, including chapters on Phase Behavior of Fat Mixtures and the Rheology and Mechanical Properties of Fats Methods Used in the Study of the Physical Properties of Fats (including a new section on microscopy).

  • Fully revised and updated with 30% new content, including new chapters on Phase Behavior of Fat Mixtures, Rheology and Mechanical Properties of Fats, and Methods Used in the Study of the Physical Properties of Fats
  • Includes a new section on microscopy
  • Presents the principles behind X-ray diffraction, crystallization theory, and the mechanics of fats
  • Provides theory for foundational understanding, examples for real-world insight, and tips for improving applied results
The Skin: Structure, Biochemistry, Function and Testing for Cosmetic Formulators

Автор: , McMullen Roger L., Wickett Randall R.
Название: The Skin: Structure, Biochemistry, Function and Testing for Cosmetic Formulators
ISBN: 0820604038 ISBN-13(EAN): 9780820604039
Издательство: Mare Nostrum (Eurospan)
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Цена: 21760.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The new 9th edition of Harry's Cosmeticology is available as a three-volume set containing over 2,600 pages of new information on the recent changes in the cosmetic and personal care industry. Chemical Publishing is now offering key parts of the title for those interested in a particular subject area covered in the book with a new line of ‘Focus Books’ for this purpose. Each Focus Book contains a series of selected chapters that can be used as a reference guide for a particular subject area. This focus book covers The Skin: Structure, Biochemistry, Function and Testing for Cosmetic Formulators.

Supramolecular Structure and Function

Автор: Greta Pifat-Mrzljak
Название: Supramolecular Structure and Function
ISBN: 3642709079 ISBN-13(EAN): 9783642709074
Издательство: Springer
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Цена: 18284.00 р.
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Описание: During the past decade we have witnessed not only an increase in knowledge of the "traditional" biophysical problems, but also an understanding of the molecular basis of various biological phenomena.


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