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Resistance to Targeted Therapies in Lymphomas, Ana C. Xavier; Mitchell S. Cairo


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Автор: Ana C. Xavier; Mitchell S. Cairo
Название:  Resistance to Targeted Therapies in Lymphomas
ISBN: 9783030244231
Издательство: Springer
Классификация:

ISBN-10: 3030244237
Обложка/Формат: Hardcover
Страницы: 210
Вес: 0.52 кг.
Дата издания: 2019
Серия: Resistance to Targeted Anti-Cancer Therapeutics
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 25 tables, color; 26 illustrations, color; 1 illustrations, black and white; xx, 210 p. 27 illus., 26 illus. in color.
Размер: 234 x 156 x 14
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Over the past few decades, lymphoma patient outcomes have improved as a result of multidrug chemotherapy and radiation therapy, intensification of treatment, improvement in supportive care, and better imaging and staging systems. Even more recently, there has been tremendous progress in the understanding of cancer cell biology and its microenvironment which has resulted in the development of biologic agents, also called target therapies. These therapies are more specific in targeting cancer cells either directly or via enhancement of the immune system. Many clinical studies have focused on biological agents in combination with traditional chemotherapy with the goal of improved outcomes, or reduced acute long term complications that are associated with lymphoma therapy. This volume will review different classes of target drugs that have been developed, approved, or are under investigation in the field of lymphoma therapy. The discussion will not only be on the understanding of the mechanisms of action or clinical response of those agents, but will also help the reader to understand the nature of lymphoma biology in patients who relapse or are refractor after exposure to those drugs. Contributors will discuss what is currently known about mechanisms of tumor-related or host-related resistance, and how to overcome this resistance. This understanding is crucial given the dismal outcomes of patients with relapsed or refractory lymphomas. The book provides a unique opportunity to review and reflect on the recent successes and pitfalls of the modern lymphoma therapy era.
Дополнительное описание: Mechanisms of Glucocorticoid Response and Resistance in Lymphoid Malignancies.- Resistance to Monoclonal Antibody Therapeutics in Lymphoma.- Resistance to Antibody-Drug Conjugate.- Resistance to Proteasome Inhibitor Therapy in Non-Hodgkin Lymphoma.- Resis



Resistance of Targeted Therapies Excluding Antibodies for Lymphomas

Автор: Ferreri
Название: Resistance of Targeted Therapies Excluding Antibodies for Lymphomas
ISBN: 3319751832 ISBN-13(EAN): 9783319751832
Издательство: Springer
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Цена: 16769.00 р.
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Описание: In the last decade, the literature on molecular mechanisms and activated pathways in the different lymphoma categories increased exponentially, which was followed by a more diffuse and successful use of targeted therapies.

Malignant Lymphomas Other than Hodgkin`s Disease

Автор: Karl Lennert
Название: Malignant Lymphomas Other than Hodgkin`s Disease
ISBN: 3642810942 ISBN-13(EAN): 9783642810947
Издательство: Springer
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Цена: 12157.00 р.
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Описание: First, there is a chapter on normal cytology that supplements and, in some respects, revises the presentation given in Part A of this Handbook (1961). The second chapter is a brief description of the light-microscopic techniques that are used in our laboratories and have proved to be suitable for a precise diagnosis of lymph-node diseases.

MALT Lymphomas

Автор: Zucca Emanuele, Bertoni Francesco
Название: MALT Lymphomas
ISBN: 0306479869 ISBN-13(EAN): 9780306479861
Издательство: Springer
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Цена: 19564.00 р.
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Описание: MALT Lymphomas is a multidisciplinary book that covers all the aspects of MALT lymphomas, from the molecular biology, the aetiology and the pathology, to all the possible therapeutic approaches. Extranodal marginal zone B cell lymphoma of MALT type (MALT lymphoma) is one of the lymphoma subtypes that has allowed us some of the most interesting steps forward in the understanding and treatment of human cancers. The eight contributions have been written by a team of international experts and represent an essential reading for oncologists, haematologists, gastroenterologists, pathologists and all the other physicians and researchers involved in cancer. The book is also supported by a series of figures illustrating the histology and the clinical features and the treatment.

Pediatric Lymphomas

Автор: Howard J. Weinstein; Melissa M. Hudson; Michael P.
Название: Pediatric Lymphomas
ISBN: 3642057969 ISBN-13(EAN): 9783642057960
Издательство: Springer
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Цена: 23058.00 р.
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Описание: This is a comprehensive textbook of Hodgkin`s and non-Hodgkin`s lymphomas written by leaders in the field of childhood lymphomas. The book is at the level of subspecialists in pediatric hematology and oncology, radiation oncology, pediatric surgery and hematopathology.

Rare Lymphomas

Автор: Dreyling
Название: Rare Lymphomas
ISBN: 3642395899 ISBN-13(EAN): 9783642395895
Издательство: Springer
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Цена: 23058.00 р.
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Описание: After a decade of tremendous progress in the diagnostic and therapeutic approaches to malignant lymphoma, optimal treatment strategies are now based not only on accurate diagnosis but also on thorough evaluation of clinical and molecular risk factors.

Aggressive Lymphomas

Автор: Lenz
Название: Aggressive Lymphomas
ISBN: 3030003612 ISBN-13(EAN): 9783030003616
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This book summarizes current knowledge of the biology and molecular pathogenesis of aggressive lymphomas and reviews the state of the art in diagnostic and therapeutic strategies.

Pediatric lymphomas

Автор: Weinstein
Название: Pediatric lymphomas
ISBN: 3540203567 ISBN-13(EAN): 9783540203568
Издательство: Springer
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Цена: 23058.00 р.
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Описание: Covers the epidemiology, pathology, molecular biology, clinical features, diagnosis, and treatment of Hodgkin and non-Hodgkin lymphomas in children and adolescents. This book is useful for sub-specialists in pediatric hematology and oncology, radiation oncology, pediatric surgery and hematopathology.

Histopathology of Non-Hodgkin`s Lymphomas

Автор: Alfred C. Feller; M. Soehring; M. Paulli; M. Engel
Название: Histopathology of Non-Hodgkin`s Lymphomas
ISBN: 364297189X ISBN-13(EAN): 9783642971891
Издательство: Springer
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Цена: 15372.00 р.
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Описание: (Based on the WHO Classification)

Atlas of Cutaneous Lymphomas

Автор: Joi B. Carter; Amrita Goyal; Lyn McDivitt Duncan
Название: Atlas of Cutaneous Lymphomas
ISBN: 3319354779 ISBN-13(EAN): 9783319354774
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This atlas contains excellent clinical and histopathologic images and text of each of the types of cutaneous lymphoma (around 25 entities).

Tumours, Lymphomas and Selected Paraproteinaemias

Автор: J. Verbov
Название: Tumours, Lymphomas and Selected Paraproteinaemias
ISBN: 9401076839 ISBN-13(EAN): 9789401076838
Издательство: Springer
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Цена: 23058.00 р.
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Описание: JULIAN VERBOV ix ABOUT THE EDITOR Dr Julian Verbov is Consultant Dermatologist to Liverpool Health Authority and Clinical Lecturer in Dermatology at the University of Liverpool.

T-Cell and NK-Cell Lymphomas

Автор: Querfeld
Название: T-Cell and NK-Cell Lymphomas
ISBN: 3319997157 ISBN-13(EAN): 9783319997155
Издательство: Springer
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Цена: 20962.00 р.
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Описание: In this book, a group of internationally distinguished lymphoma experts provide a comprehensive review of the most important advances in the biology, diagnosis, and therapy of T cell and NK cell malignancies.

Diagnostic Pathology: Lymph Nodes and Spleen With Extranodal Lymphomas

Название: Diagnostic Pathology: Lymph Nodes and Spleen With Extranodal Lymphomas
ISBN: 0323477798 ISBN-13(EAN): 9780323477796
Издательство: Elsevier Science
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Цена: 37138.00 р.
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Описание:

Part of the highly regarded Diagnostic Pathology series, this updated volume is a visually stunning, easy-to-use reference covering all aspects of benign and malignant lesions of lymph node, spleen, and extranodal lymphomas. Outstanding images make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. This second edition incorporates the most recent clinical, pathological, histological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice.

  • Unsurpassed visual coverage with carefully annotated gross and microscopic pathology, stains, ancillary tests, and detailed medical illustrations that provide clinically and diagnostically important information on typical and variant disease features
  • Designed to help the reader identify crucial elements of each diagnosis, along with associated differential diagnoses and pitfalls, to more quickly resolve problems during routine signout of cases
  • Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index
  • Thoroughly updated content throughout, reflecting the 2016 revision of the WHO classification of lymphoid neoplasms, the latest nomenclature of diseases, and a current review of the literature of each disease
  • New coverage of classification of B-cell lymphomas, subtypes of diffuse large B-cell lymphoma, and gray zone lymphoma; classification of T-cell lymphomas, recent genomic discoveries, and their effect in classification; and an updated review of provisional entities such as breast implant-associated anaplastic large cell lymphoma, cutaneous lymphomas, and lymphomas derived of cytotoxic lymphocytes
  • Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

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