Автор: Jan Ponten Название: Spontaneous and Virus Induced Transformation in Cell Culture ISBN: 3709182603 ISBN-13(EAN): 9783709182604 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A. Definitions of Transformation in vitro When normal tissues or organs are explanted to conditions favoring the growth of cells as individual units ("cell culture"), the original cell population undergoes a large variety of modifications. Only a minority of the cells will thrive and multiply and within a rather short period of time, the complex composition of the original explant is replaced by a much simplified one of only a few recogniz- ably different cell types. With most organs fibroblast-like cells survive longest and outgrow other types. This is then a stable state of affairs for many gener- ations. This treatise will not discuss whether this simplification and stabilization represents selection of certain pre-existing cell types or a modification of cells into only a few recognizably different categories; for an excellent review see HARRIS. (1964). Table 1. Terminology Employed to Describe Transformations in vitro Type of transformation Essential features Irregular growth Lack of contact inhibition of cell membrane movement ("ruffled membranes") between juxtaposed cells Unrestrained growth Deficient inhibition of the cell cycle (mitosis) in a crowded culture Infinite growth Capacity of cells to undergo an infinite number of di- visions (formation of established cell lines) Cells may depart from this typical behavior in numerous ways involving for instance cellular morphology, immunology, chromosomes or metabolism. Such changes have, sometimes rather vaguely, been called "transformations". This is unprecise and the term "transformation" will here be used exclusively to indicate disturbances in cell growth related to neoplasia.
Автор: Eglen Название: Muscarinic Receptor Subtypes in Smooth Muscle ISBN: 0849385490 ISBN-13(EAN): 9780849385490 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Explores several subtypes of muscarinic receptors that modulate smooth muscle activity. This book contains topics such as a classification of muscarinic receptors, biochemical responses that occur in smooth muscle, and the role of muscarinic receptors in the function of gastrointestinal and genitourinary smooth muscle.
Описание: The latter part of the 3rd millennium BC witnessed severe dislocations in the social, economic and political structures of the lands at the eastern end of the Mediterranean Sea - the Levant. This volume contains the papers given at a conference held in 2004 at the British Museum, presenting both new evidence and new theories bearing on this transitional period.
Автор: David Raeburn; Mark A. Giembycz Название: Airways Smooth Muscle ISBN: 3034875606 ISBN-13(EAN): 9783034875608 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Many factors may influence the release of neurotransmitters from airway nerves [1]. There are marked differences be- tween species in airway innervation and in neuromodulatory effects and, wherever possible, studies in human airways have been emphasised, although information on neuromodulation in human airways is some- what limited at present.
Автор: David Raeburn; Mark A. Giembycz Название: Airways Smooth Muscle: Modelling the Asthmatic Response In Vivo ISBN: 3034898630 ISBN-13(EAN): 9783034898638 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Building on the existing titles in the "Airways Smooth Muscle" sub-series, the sixth volume explores physiological and pharmacological processes in the lung in vivo.
Автор: Eberhard Betz Название: Vascular Smooth Muscle / Der Gef??muskel ISBN: 3540057110 ISBN-13(EAN): 9783540057116 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book summarizes the papers presented at the International Symposium on vascular smooth muscle, organized in combination with the XXV Interna- tional Congress of Physiological Sciences by the German Society of Angiology e. V. Honorary Presidents were Professor Dr. Dr. h. c. K. Wezler and Profes- sor Dr. Dr. h. c. H. E. Bock. The annual meeting of the SOCiety of Angiology was combined with the Symposium. It was held at the Physiological Institute of the University of TUBINGEN, an appropriate setting, since in the last century numerous scientists from this institute were engaged in special problems con- nected with the vascular system and muscles. The topics of this meeting covered a wide field of vascular research; it was the aim of the organizers to the discuss the physiological, biochemical and morphological basis of the vascular muscles with clinicians and to stress some important aspects in the form of round table discussions. On the following pages the reader will therefore find numerous papers on spe- cial basic problems of the physiology, biochemistry and morphology of vascu- lar smooth muscle as well as on pathophysiological and pathological changes and papers about the clinical treatment of vascular disorders. The more ex- perimental and theoretical papers and discussions are concerned with the sin- gle smooth muscle cell and the different types of vessels in various organs whereas the discussion of the clinical sections concentrate on the coronary system.
Автор: Yong-Xiao Wang Название: Calcium Signaling In Airway Smooth Muscle Cells ISBN: 3319374583 ISBN-13(EAN): 9783319374581 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book features novel findings in the studies of the molecular genesis, networks, microdomains, regulation, and physiological functions of calcium signaling in animal and human airway SMCs.
Описание: When normal sleep patterns have been interrupted, learning to relax in some deeper ways can assist breaking the negative patterns and re-establishing the natural sleep that your body was designed for. This CD has been shown to help individuals reclaim natural and normal sleep after bouts with insomnia. It actually takes a lot of effort to block a p
Автор: Edwin Daniel Название: Smooth Muscle ISBN: 1468427539 ISBN-13(EAN): 9781468427530 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: One of the purposes of this volume is to provide pharmacologists with some understanding of the physiology, biophysics, and bio- chemistry of smooth muscle and of related advances in methodology so as to facilitate the incorporation of such knowledge and related methods into future pharmacological studies of smooth muscle and drug interactions.
Автор: Theodora Szasz, Rita C. A. Tostes Название: Vascular Smooth Muscle Function in Hypertension ISBN: 1615046844 ISBN-13(EAN): 9781615046843 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 5016.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Hypertension is defined by an increase in systemic blood pressure above limits considered normal. In this work, rather than providing the exhaustive list of modifications in the blood pressure regulating systems that ultimately affect the vasculature in hypertension, we will focus on the structural and functional alterations of vascular smooth muscle per se during hypertension.
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