Автор: Gary P. Moss; Darren R. Gullick; Simon C. Wilkinso Название: Predictive Methods in Percutaneous Absorption ISBN: 3662508311 ISBN-13(EAN): 9783662508312 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book sheds new light on the development and use of quantitative models to describe the process of skin permeation.
Автор: Gary P. Moss; Darren R. Gullick; Simon C. Wilkinso Название: Predictive Methods in Percutaneous Absorption ISBN: 3662473704 ISBN-13(EAN): 9783662473702 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book sheds new light on the development and use of quantitative models to describe the process of skin permeation. It critically reviews the development of quantitative predictive models of skin absorption and discusses key recommendations for model development. Topics presented include an introduction to skin physiology; the underlying theories of skin absorption; the physical laboratory-based processes used to generate skin absorption data, which is in turn used to construct mathematical models describing the skin permeation process; algorithms of skin permeability including quantitative structure-activity (or permeability) relationships (QSARs or QSPRs); relationships between permeability and molecular properties; the development of formulation-focused approaches to models of skin permeability prediction; the use of artificial membranes, e.g. polydimethylsiloxane as alternatives to mammalian skin; and lastly, the use of novel Machine Learning methods in developing the next generation of predictive skin permeability models. The book will be of interest to all researchers in academia and industry working in pharmaceutical discovery and development, as well as readers from the field of occupational exposure and risk assessment, especially those whose work involves agrochemicals, bulk chemicals and cosmetics.
Автор: J.W. Gorrod; J. Wahren Название: Nicotine and Related Alkaloids ISBN: 940104936X ISBN-13(EAN): 9789401049368 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Nicotine is an alkaloid which is present, together with a number of minor alkaloids, in tobacco and a wide variety of other plants.
Автор: D.J. Atherton Название: Pharmacology of the Skin II ISBN: 3642740561 ISBN-13(EAN): 9783642740565 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes analytical methods used to estimate the processes set in motion by percutaneous absorption of UV filters in sunscreen cosmetic products. It details these methods in both in vitro and non-invasive in vivo methodologies.
Описание: This book describes analytical methods used to estimate the processes set in motion by percutaneous absorption of UV filters in sunscreen cosmetic products. It details these methods in both in vitro and non-invasive in vivo methodologies.
Автор: Dragicevic Nina, Maibach Howard Название: Percutaneous Absorption: Drugs, Cosmetics, Mechanisms, Methods ISBN: 1138351237 ISBN-13(EAN): 9781138351233 Издательство: Taylor&Francis Рейтинг: Цена: 32921.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Updating and expanding the scope of topics covered in the previous edition, Percutaneous Absorption supplies new studies on the role of the skin as a key portal of entry for chemicals into the body this book serves as a detailed reference source for recent advances in the field, as well as an experimental guide for laboratory personnel.
Автор: Riviere, Jim E. Название: Percutaneous Absorption ISBN: 1574448692 ISBN-13(EAN): 9781574448696 Издательство: Taylor&Francis Рейтинг: Цена: 30624.00 р. Наличие на складе: Нет в наличии.
Автор: Washington Название: Physiological Pharmaceutics ISBN: 0748405623 ISBN-13(EAN): 9780748405626 Издательство: Taylor&Francis Рейтинг: Цена: 16843.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It is the aim of innovative pharmaceutical scientists to design the new dosage forms to overcome the body`s barrier mechanisms which have specifically evolved to exclude foreign material. This book provides an integrated approach to the study of drug formulation in the body with the emphasis on the formulation variables rather than the drugs.
Development of strategies to assist the movement of poorly permeable molecules across biological barriers has long been the goal of drug delivery science. In the last three decades, there has been an exponential increase in advanced drug delivery systems that aim to address this issue. However, most proprietary delivery technologies that have progressed to clinical development are based on permeation enhancers (PEs) that have a history of safe use in man. This Special Issue entitled "Transmucosal Absorption Enhancers in the Drug Delivery Field" aims to present the current state-of-the-art in the application of PEs to improve drug absorption. Emphasis is placed on identification of novel permeation enhancers, mechanisms of barrier alteration, physicochemical properties of PEs that contribute to optimal enhancement action, new delivery models to assess PEs, studies assessing safety of PEs, approaches to assist translation of PEs into effective oral, nasal, ocular and vaginal dosage forms and combining PEs with other delivery strategies.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
