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Neurons and the DHA Principle, Valentine, Raymond C. , Valentine, David L.


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Автор: Valentine, Raymond C. , Valentine, David L.
Название:  Neurons and the DHA Principle
ISBN: 9780367380748
Издательство: Taylor&Francis
Классификация:


ISBN-10: 0367380749
Обложка/Формат: Paperback
Страницы: 288
Вес: 0.53 кг.
Дата издания: 20.12.2019
Язык: English
Размер: 154 x 235 x 16
Читательская аудитория: Tertiary education (us: college)
Основная тема: Nutrition
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Европейский союз
Описание:

Studies with bacteria and other systems suggest that the omega-3 fatty acid DHA confers great benefits to neurons in maximizing both speed of neural impulses and energy efficiency. Unfortunately, studies also show that DHAs ease of oxidation damages membrane integrity. Exploring this duality, Neurons and the DHA Principle proposes a new model for the causes of neurodegeneration, in which DHA-enriched membranes of neurons become dysfunctional and energetically wasteful, triggering the premature death of neurons.

The challenge of this book is to digest how DHA acts as an essential building block of neurons while also conspiring for their assassination during aging. As the book reviews the extraordinary properties of DHA in life forms from deep-sea bacteria to human neurons, it asks:

  • Is there a trade-off between speed and efficiency of brain function enabled by DHA versus longevity or life span?
  • Has modern medicine advanced significantly in the treatment of the body but not necessarily of the brain?
  • What are the molecular explanations for the decline in brain health during the age of longevity?

A full accounting of the roles of DHA in neurons requires balancing the enormous benefits of these molecules against the risks. Introducing the dual chemical personalities of DHA from an evolutionary perspective, Neurons and the DHA Principle explores DHA from the standpoint of benefit-risk analysis, opening new perspectives for understanding how DHA functions in neurons.




Techniques to Investigate Mitochondrial Function in Neurons

Автор: Stefan Strack; Yuriy M. Usachev
Название: Techniques to Investigate Mitochondrial Function in Neurons
ISBN: 1493968882 ISBN-13(EAN): 9781493968886
Издательство: Springer
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Цена: 20962.00 р.
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Описание:

Neuromethods Preface...
Preface...
Table of Contents...
Contributing Authors...

1. Three-Dimensional Reconstruction of Neuronal Mitochondria by Electron Tomography
Guy Perkins

2. Measuring Mitochondrial Shape with ImageJ
Ronald A. Merrill, Kyle H. Flippo, and Stefan Strack

3. Live Imaging Mitochondrial Transport in Neurons
Meredith M. Course, Chung-Han Hsieh, Pei-I Tsai, Jennifer A. Codding-Bui, Atossa Shaltouki, and Xinnan Wang

4. Techniques to Investigate Bioenergetics of Mitochondria
William I. Sivitz

5. Respirometry in Neurons
Liang Zhang and Eugenia Trushina

6. Measuring ATP in Axons with FRET
Lauren Y. Shields, Bryce A. Mendelsohn, and Ken Nakamura

7. Characterizing Metabolic States using Fluorescence Lifetime Imaging Microscopy (FLIM) of NAD(P)H
Thomas S. Blacker and Michael R. Duchen

8. Techniques for Simultaneous Mitochondrial and Cytosolic Ca2+ Imaging in Neurons
Jacob E. Rysted, Zhihong Lin, and Yuriy M. Usachev

9. Live Imaging of Mitochondrial ROS Production and Dynamic Redox Balance in Neurons
Karolina Can, Sebastian Kьgler, and Michael Mьller

10. Monitoring of Permeability Transition Pore Openings in Isolated Individual Brain Mitochondria
Nickolay Brustovetsky and Tatiana Brustovetsky

11. Examination of Mitochondrial Ion Conductance by Patch Clamp in Intact Neurons and Mitochondrial Membrane Preparations
Elizabeth A. Jonas and Nelli Mnatsakanyan

12. Monitoring of Permeability Transition Pore Openings in Mitochondria of Cultured Neurons
Tatiana Brustovetsky and Nickolay Brustovetsky

13. Protocols for Assessing Mitophagy in Neuronal Cell Lines and Primary Neurons
Ruben K. Dagda and Monica Rice

14. Examining Mitochondrial Function at Synapses In Situ
Gregory T. Macleod and Maxim V. Ivannikov

15. Proteomic Analysis of Neuronal Mitochondria
Kelly L. Stauch and Howard S. Fox

16. Measuring Mitochondrial Pyruvate Oxidation
Lawrence R. Gray, Alix A.J. Rouault, Lalita Oonthonpan, Adam J. Rauckhorst, Julien A. Sebag, and Eric B. Taylor

Interaction Between Neurons and Glia in Aging and Disease

Автор: Ana Cristina Rego; Joao Malva; Rodrigo Cunha; Cata
Название: Interaction Between Neurons and Glia in Aging and Disease
ISBN: 0387708294 ISBN-13(EAN): 9780387708294
Издательство: Springer
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Цена: 28734.00 р.
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Описание: A superb source of reference reviews as well as a concise overview of the functional cross-talk between neurons and glial cells, this book also focuses on microglia and inflammation in the aging brain and in neurological disorders.

Adrenergic Neurons

Автор: Geoffrey Burnstock and Marcello Costa
Название: Adrenergic Neurons
ISBN: 0412140608 ISBN-13(EAN): 9780412140600
Издательство: Springer
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Цена: 12157.00 р.
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Identified Neurons and Behavior of Arthropods

Автор: Graham Hoyle
Название: Identified Neurons and Behavior of Arthropods
ISBN: 146846969X ISBN-13(EAN): 9781468469691
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Identified Neurons and Behavior of Arthropods presents for the larger audience the papers delivered at a symposium of the same title. But in this subject, the role of identified nerve cells in determining behavior, Wiersma stood virtually alone for 30 years.

Development and Engineering of Dopamine Neurons

Автор: Jeroen Pasterkamp; Marten P. Smidt; J. Peter H. Bu
Название: Development and Engineering of Dopamine Neurons
ISBN: 1441903216 ISBN-13(EAN): 9781441903211
Издательство: Springer
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Цена: 23757.00 р.
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Описание: The initial identification of dopamine as a neurotransmitter in the central nervous system (CNS) and its relevance to psychiatric and neurological disorders have stimulated a plethora of neurochemical, pharmacological and genetic studies into the function of dopamine neurons and theirprojections.

Concussion Is Brain Injury: Treating the Neurons and Me

Автор: Jeejeebhoy Shireen
Название: Concussion Is Brain Injury: Treating the Neurons and Me
ISBN: 0991969863 ISBN-13(EAN): 9780991969869
Издательство: Неизвестно
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Цена: 3677.00 р.
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Описание:

Shireen is an artist, author, and blogger. She earned a B.Sc. in psychology from the University of Toronto, launched into writing and computer programming, and slammed and somersaulted into the unknown life of brain injury in the year 2000.

She emerged from the car crash still walking and talking, but the person she had been was forever gone. Although no one knew it at the time, she had sustained a concussion. The repercussions of that injury have shaped her life ever since.

Many believe a concussion is a mild injury, when in truth it is a traumatic brain injury in which the brain bangs about inside the skull. If not identified or treated within the first 48 hours, the injury can lead to secondary symptoms (euphemistically named post-concussive syndrome) that require years of rehabilitation. Traditional rehabilitation, involving cognitive therapy and rest, were ineffective. In addition to lost neurons, Jeejeebhoy was quickly losing her social connections and relationships. The concussion was threatening to cut her off from the world.

She wanted this hidden injury healed; she wanted the plethora of problems from it, especially the cognitive ones, treated. She wanted to return to society. And so began her long quest to find effective treatment. She found it and improved dramatically. In Concussion Is Brain Injury, Revised Edition, Jeejeebhoy shares this journey, her discoveries, and the latest research to give hope to those who have suffered from concussions and the people who care for them.

Birth, Life and Death of Dopaminergic Neurons in the Substantia Nigra

Автор: di Giovanni
Название: Birth, Life and Death of Dopaminergic Neurons in the Substantia Nigra
ISBN: 3709110920 ISBN-13(EAN): 9783709110928
Издательство: Springer
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Цена: 38992.00 р.
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Описание: This book provides a unique multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and pathology of the substantia nigra pars compacta (SNc) dopaminergic neurons. The book bridges basic science and clinical practice.


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