Actin Cytoskeleton in Cancer Progression and Metastasis Part A, Volume 355, in the International Review of Cell and Molecular Biology series provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response.
Описание: The processes of tumor metastasis, apoptosis and anti-tumor immune response are among the most complex yet rapidly advancing fields in the area of cancer research. This monograph, with its leading authorship, presents a comprehensive coverage of the recent advances in the various key concepts in these fundamental aspects of human cancer.
Описание: Proprotein convertases (PCs) are a family of proteases including PC1, PC2, Furin, PC4, PACE4, PC5, and PC7. This title discusses a number of previous and recent findings on the PCs features, their implication in the regulation of multiple cellular functions that impact on the invasive/metastatic potential of cancer cells, and their clinical relevance in cancer patients.
Автор: Jonathan M. Lee Название: The Actin Cytoskeleton and the Regulation of Cell Migration ISBN: 1615043888 ISBN-13(EAN): 9781615043880 Издательство: Mare Nostrum (Eurospan) Цена: 9286.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The mammalian cytoskeleton is an internal framework of actin, tubulin, and intermediate filament proteins. Proteins of these three classes assemble non-covalently into filamentous polymers that support the structural integrity of the relatively fragile lipid plasma membrane. In addition, cytoskeletal polymers provide the mechanical strength that hold a cell together and anchor it to its growth substrate. The cytoskeleton must also have the capacity for rapid and substantial remodeling and provide the motive and tractor force necessary to drive motility. As such, the cytoskeleton has a functional duality: sufficiently rigid to prevent plasma membrane deformation but pliable enough to allow for cytokinesis; sufficiently adhesive to allow for traction but dynamic enough to allow movement from one place to another. A major research challenge in cytoskeleton biology is to understand how cytoskeletal proteins assemble and dissemble in support of physiological processes. This chapter will focus on the role of the actin cytoskeleton in cell migration. More specifically, we will focus on the actin cytoskeleton of vertebrate cells.
Автор: Hans Georg Mannherz Название: The Actin Cytoskeleton and Bacterial Infection ISBN: 3319500465 ISBN-13(EAN): 9783319500461 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells.
Описание: Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics, tumor microenvironment can also be a target and mediator of both standard and newly-emerging forms of cancer therapeutics.
Автор: Yaroslav B. Blume; W. Vance Baird; Alla I. Yemets; Название: The Plant Cytoskeleton: a Key Tool for Agro-Biotechnology ISBN: 1402088418 ISBN-13(EAN): 9781402088414 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The cytoskeleton is a key intracellular structure governing relevant processes such as cell division, growth, molecule trafficking, and response to internal and external signals. This work deals with the cytoskeleton as the `server` for these numerous and multi-tasked nodes. It presents achievements attained in basic research of the cytoskeleton.
Автор: A.D. Bershadsky; J.M. Vasiliev Название: Cytoskeleton ISBN: 1468452800 ISBN-13(EAN): 9781468452808 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book, like other monographs of the Cellular Organelles series, is not a comprehensive review, but an introduction to the study of cytoskeleton. these citations are given to help the reader find the source of certain new data and theories, which are not discussed at length in the reviews.
Описание: The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon, a new volume in the Methods in Cell Biology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in neuronal cells, and includes sections on such topics as actin transport in axons and neurofilament transport
Автор: Yaroslav B. Blume; W. Vance Baird; Alla I. Yemets; Название: The Plant Cytoskeleton: a Key Tool for Agro-Biotechnology ISBN: 1402088426 ISBN-13(EAN): 9781402088421 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The cytoskeleton is a key intracellular structure governing relevant processes such as cell division, growth, molecule trafficking, and response to internal and external signals. This work deals with the cytoskeleton as the `server` for these numerous and multi-tasked nodes. It presents achievements attained in basic research of the cytoskeleton.
Автор: Ralph A. Nixon; Aidong Yuan Название: Cytoskeleton of the Nervous System ISBN: 1493951424 ISBN-13(EAN): 9781493951420 Издательство: Springer Рейтинг: Цена: 49631.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cytoskeleton of the Nervous System provides an overview of the cytoskeleton in axonal development and pathology. Readers will find detailed descriptions of microtubules, neurofilaments and interacting proteins, in addition to the significance of the neuronal cytoskeleton in health and disease.
Автор: Manfred Schliwa Название: The Cytoskeleton ISBN: 3709176697 ISBN-13(EAN): 9783709176696 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The term cytoskeleton has become firmly established in today`s scientific vocabulary. Since then, the modern field of research on the structural organization of the cytoplasm has turned into one of the most productive and rapidly expanding research areas in Cell Biology today.
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