Economic Evaluation In Genomic And Precision Medicine, Mitropoulou, Christina
Автор: Anthony J.F. Griffiths, John Doebley, Catherine Pe Название: An Introduction to Genetic Analysis ISBN: 1319114776 ISBN-13(EAN): 9781319114770 Издательство: Macmillan Learning Рейтинг: Цена: 15244.00 р. Наличие на складе: Нет в наличии.
Описание: The evolution of a classicThe new 12th edition of Introduction to Genetic Analysis takes this cornerstone textbook to the next level.
Автор: T. Brown Название: Genomes 4 ISBN: 0815345089 ISBN-13(EAN): 9780815345084 Издательство: Taylor&Francis Рейтинг: Цена: 9645.00 р. Наличие на складе: Нет в наличии.
Описание:
Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids.
Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important.
Each chapter has a set of short-answer questions, in-depth problems, and annotated further reading. There is also an extensive glossary. Genomes 4 is the ideal text for upper level courses focused on genomes and genomics.
Автор: Miedaner, Thomas Название: Applications of Genetic and Genomic Research in Cereals ISBN: 0081021631 ISBN-13(EAN): 9780081021637 Издательство: Elsevier Science Рейтинг: Цена: 32844.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Genetic and genomic research has and will continue to have fundamental impact on the future of plant breeding. Cereals are the crops with the highest impact worldwide, providing more than 50% of the calories of human mankind. Given projected population growth in the next decades, the challenges of global climate change, and the growing demand for qualitatively high feed for our animals, cereal scientists and cereal breeders have to provide big efforts for the years to come. . . Applications of Genetic and Genomic Research in Cereals reviews the contributions of genetics and genomics to cultivar development that are already implemented and will become even more important in the next decade. . . This book focuses on cereals grown in temperate regions, mainly bread wheat, durum wheat, and barley, but will cover also breeding aspects in triticale and rye. Split into three main parts Applications of Genetic and Genomic Research in Cereals covers the outreach of these new techniques for practical breeding in a first part, as well as covering genetic and genomic approaches for improving special traits - drought tolerance, biotic stress, biomass production and more in the second part. The final part discusses the impact of modern techniques on practical breeding including hybrid breeding, genetic diversity, genomic selection. . Written by an international team of top acadmics and edited by an expert in the field Applications of Genetic and Genomic Research in Cereals will be of value to academics working in the agricultural sciences the book will also be essential reading for professionals working in plant breeding.
Автор: Henrich, Vincent Название: Henrich-Managing Patient Health in the Genomic Era ISBN: 0128160152 ISBN-13(EAN): 9780128160152 Издательство: Elsevier Science Рейтинг: Цена: 17854.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
In recent years genomic medicine has grown from a new medical science to an implementable set of clinical methods and technologies whose concrete applications are revolutionizing the health sector. However, most primary care and family health practitioners still have limited experience employing genetic and genomic approaches effectively in their daily practice.
In Managing Patient Health in the Genomic Era: Family Health History and Chronic Disease Risk, Drs. Vincent Henrich, Lori Orlando, and Brian Shirts discuss the practical considerations surrounding the use of genomic and genetic tests to manage patient health, provide adult disease risk assessment, improve diagnosis, and support effective interventions and treatment. In ten chapters, evidence-based information and case studies are described and examine the central place of family health history (FHH) in genomic medicine, tools and strategies for compiling and analysing family health history, how to identify existing and novel genetic markers, how to identify lineage specific (or rare) variants within families, and how to find effective interventions based on genetic testing results and FHH. Factors which influence clinical practice, including gene-environment interactions, FHH social networking, direct to consumer (DTC) genetic testing and data sharing, algorithms for analyzing genetic data, and patient counseling are discussed from the standpoint of clinical practice.
Here frontline healthcare providers will discover succinct commentary and key examples to assist with their local needs. Relevant principles of genetic biology and inheritance are explored and guidance on available support networks and online resources is also provided.
Presents a practical, accessible resource for primary care providers, allied health professionals, pharmacologists, public health professionals, students and clinical researchers
Addresses genetic and genomic approaches in managing patient health, conducting and analyzing family health histories, and assessing adult disease risk
Features an expert author team with direct experience integrating genetics and genomics in primary care and family medicine settings
Examines the attributes and limitations of family health history, genetic testing, and genomic testing in clinical practice
Includes detailed explanations following practice-based examples
Автор: Smith, V. Anne Название: Code for carolyn ISBN: 303004551X ISBN-13(EAN): 9783030045517 Издательство: Springer Рейтинг: Цена: 3492.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Carolyn`s parents did not, after all, make genomics history by synthesizing her genome in a lab.
Название: Genomic designing of climate-smart oilseed crops ISBN: 3319935356 ISBN-13(EAN): 9783319935355 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book highlights modern strategies and methods to improve oilseed crops in the era of climate change, presenting the latest advances in plant molecular breeding and genomics-driven breeding. Spectacular achievements in the fields of molecular breeding, transgenics and genomics in the last three decades have facilitated revolutionary changes in oilseed- crop-improvement strategies and techniques. Since the genome sequencing of rice, as the first crop plant, in 2002, the genomes of about one dozen oilseed crops have been sequenced and more are to follow. This has made it possible to decipher the exact nucleotide sequence and chromosomal positions of agroeconomic genes. Most importantly, comparative genomics and genotyping-by-sequencing have opened up new vistas for exploring available biodiversity, particularly of wild crop relatives, for identifying useful donor genes.
Автор: Kollmar Название: Eukaryotic Genomic Databases ISBN: 1493977369 ISBN-13(EAN): 9781493977369 Издательство: Springer Рейтинг: Цена: 18866.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume explores databases containing genome-based data and genome-wide analyses. This book covers databases from all eukaryotic taxa, except plants. The chapters describe database contents and classic use-cases, which assist in accessing eukaryotic genomic data and encouraging comparative genomic research.
Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Eukaryotic Genomic Databases: Methods and Protocols is a valuable resource for geneticists and molecular biologists who are interested in the latest eukaryotic genomics data. The chapters 'PomBase: The Scientific Resource for Fission Yeast' and 'The Ensembl Genome Browser: Strategies for Accessing Eukaryotic Genome Data' are available open access under a CC BY 4.0 license via link.springer.com.
Описание: Sudden cardiac death is the leading cause of non-traumatic mortality in young (This book aims to provide an overview of the genetic and clinical aspects of SCD in young athletes, with particular emphasis on the specific issues related to diagnosis and management that these unique group of individuals pose to a physician. Specific diagnostic and management dilemmas will be illustrated through clinical cases and the most up-to-date guidelines regarding participation in sport outlined.
Автор: Yoshiji Yamada Название: Molecular Genetics of Stroke ISBN: 1615043705 ISBN-13(EAN): 9781615043705 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 6237.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent genome-wide association studies have identified various loci and genes that confer susceptibility to ischemic stroke or intracranial aneurysm. Such studies may provide insight into the function of implicated genes as well as into the role of genetic factors in the development of ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage.
Автор: Johnathan Cooper-Knock, Pamela Shaw, Thomas Jenkins Название: Clinical and Molecular Aspects of Motor Neuron Disease ISBN: 1615044280 ISBN-13(EAN): 9781615044283 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 9286.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Summarises both current clinical management of motor neuron disease (MND) and our present understanding of the molecular pathogenesis of MND. Study of C9ORF72-MND has the potential to rapidly advance both of these aspects in the coming years.
Автор: Meena Balasubramanian Название: Clinical and Molecular Heterogeneity of Osteogenesis Imperfecta ISBN: 1615047441 ISBN-13(EAN): 9781615047444 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 3762.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Osteogenesis imperfecta (OI) is a disease encompassing a group of disorders mainly characterized by bone fragility and is the commonest form of heritable bone fragility. In this book, the clinical presentations with particular emphasis on rare phenotypes associated with OI are discussed together with molecular advances in diagnosis and treatment of OI.
Автор: Emmert-Buck Michael R., Rosenberg Avi Z., Tangrea Michael A. Название: Pathological Specimens and Genomic Medicine - Emerging Issues ISBN: 9813276223 ISBN-13(EAN): 9789813276222 Издательство: World Scientific Publishing Рейтинг: Цена: 21384.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Pathological Specimens and Genomic Medicine -- Emerging Issues surveys various fields and medical disciplines related to the implementation of the new field of genomic medicine. The book includes sections on specimen processing, the effects of tissue fixation and storage impact on downstream molecular assays, image analysis and its role in the pathology workflow, molecular evaluation of samples, and how to present data to clinicians. The book contains examples of cases where these innovative technologies are applied in the real world, and also presents a look in to the future of the field of genomic medicine.
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