Applied Genomics And Public Health, Patrinos, George P.
Автор: Glaser, Anthony N. Название: High-Yield Biostatistics, Epidemiology, and Public Health. 4 ed. ISBN: 1451130171 ISBN-13(EAN): 9781451130171 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 5010.00 р. 6263.00-20% Наличие на складе: Есть (1 шт.) Описание: Provides a review of the biostatistics concepts that are tested in the USMLE Step 1. With tables, diagrams, photographs, and images to clarify important material, this book offers a concentrated, efficient review for both course exams and the USMLE.
Автор: Kishore R. Sakharkar, Meena K. Sakharkar, Ramesh Chandra Название: Post-genomic Approaches in Cancer and Nano Medicine ISBN: 8793102860 ISBN-13(EAN): 9788793102866 Издательство: Taylor&Francis Рейтинг: Цена: 13320.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Understanding the molecular mechanisms of cancer is the key for transforming cancer medicine. Seen in several cancers is a substantial proportion of human genes showing alternative splicing and mis-regulation of Pre-mRNA splicing.
Post-genomic Approaches in Cancer and Nano Medicine further investigates these matters. The first few chapters provide an update on the role of genomics in understanding alternative splicing and targets in cancer pathogenesis. Advances and prospects in applications of nanotechnology for cancer prevention, detection, and treatment are a promising field of research. The subsequent chapters provide insights on how nanotechnology-based therapeutics are moving toward revolutionizing cancer and infectious disease treatment by minimizing toxicity and facilitating targeted delivery of drugs.
Technical topics discussed in the book include: - Alternative splicing and cancer - Cancer imaging - Nanomaterials in infectious diseases - Nanomedicine in oxidative stress and cancer - Nanoparticle based drug delivery systems
Автор: David J. Balding, Ida Moltke, John Marioni Название: Handbook of Statistical Genomics ISBN: 1119429145 ISBN-13(EAN): 9781119429142 Издательство: Wiley Рейтинг: Цена: 46086.00 р. Наличие на складе: Поставка под заказ.
Описание: Previous title: Handbook of statistical genetics.
Автор: P Poltronieri Название: Applied Plant Genomics and Biotechnology ISBN: 0081000685 ISBN-13(EAN): 9780081000687 Издательство: Elsevier Science Рейтинг: Цена: 24423.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Applied plant genomics and biotechnology reviews the recent advancements in the post-genomic era, discussing how different varieties respond to abiotic and biotic stresses, investigating epigenetic modifications and epigenetic memory through analysis of DNA methylation states, applicative uses of RNA silencing and RNA interference in plant physiology and in experimental transgenics, and plants modified to produce high-value pharmaceutical proteins. The book provides an overview of research advances in application of RNA silencing and RNA interference, through Virus-based transient gene expression systems, Virus induced gene complementation (VIGC), Virus induced gene silencing (Sir VIGS, Mr VIGS) Virus-based microRNA silencing (VbMS) and Virus-based RNA mobility assays (VRMA); RNA based vaccines and expression of virus proteins or RNA, and virus-like particles in plants, the potential of virus vaccines and therapeutics, and exploring plants as factories for useful products and pharmaceuticals are topics wholly deepened. The book reviews and discuss Plant Functional Genomic studies discussing the technologies supporting the genetic improvement of plants and the production of plant varieties more resistant to biotic and abiotic stresses. Several important crops are analysed providing a glimpse on the most up-to-date methods and topics of investigation. The book presents a review on current state of GMO, the cisgenesis-derived plants and novel plant products devoid of transgene elements, discuss their regulation and the production of desired traits such as resistance to viruses and disease also in fruit trees and wood trees with long vegetative periods. Several chapters cover aspects of plant physiology related to plant improvement: cytokinin metabolism and hormone signaling pathways are discussed in barley; PARP-domain proteins involved in Stress-Induced Morphogenetic Response, regulation of NAD signaling and ROS dependent synthesis of anthocyanins. Apple allergen isoforms and the various content in different varieties are discussed and approaches to reduce their presence. Euphorbiaceae, castor bean, cassava and Jathropa are discussed at genomic structure, their diseases and viruses, and methods of transformation. Rice genomics and agricultural traits are discussed, and biotechnology for engineering and improve rice varieties. Mango topics are presented with an overview of molecular methods for variety differentiation, and aspects of fruit improvement by traditional and biotechnology methods. Oilseed rape is presented, discussing the genetic diversity, quality traits, genetic maps, genomic selection and comparative genomics for improvement of varieties. Tomato studies are presented, with an overview on the knowledge of the regulatory networks involved in flowering, methods applied to study the tomato genome-wide DNA methylation, its regulation by small RNAs, microRNA-dependent control of transcription factors expression, the development and ripening processes in tomato, genomic studies and fruit modelling to establish fleshy fruit traits of interest; the gene reprogramming during fruit ripening, and the ethylene dependent and independent DNA methylation changes.
Описание: Presents a systematic treatment of Markov chains, diffusion processes and state space models, as well as alternative approaches to Markov chains through stochastic difference equations and stochastic differential equations. This title illustrates how these processes and approaches are applied to many problems in genetics, carcinogenesis, and more.
Автор: Burdge Graham, Lillycrop Karen Название: Nutrition, Epigenetics and Health ISBN: 9813143304 ISBN-13(EAN): 9789813143302 Издательство: World Scientific Publishing Цена: 13781.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Epigenetics is emerging as an important factor in risk of diseases of global importance including obesity, cardiovascular disease and cancer. Unlike gene polymorphisms which have been the focus of understanding the role of inherited disease susceptibility for some time, epigenetic can be modified by environmental factors, in particular nutrition. Thus research into the role of epigenetics in disease has substantial potential for explaining the impact of the environmental factors such as diet on disease risk. Since epigenetic processes can be modified by nutrition, it may be possible to modify inappropriate epigenetic marks by nutritional interventions to reduce disease risk. This book will explore current understanding of the interaction between nutrition, epigenetics and disease risk, will place this knowledge in the context of global health and discuss the ethical implications of this research.
Автор: Pierce Benjamin A Название: Genetics Essentials. Concepts and Connections. - 3th ed. ISBN: 1464190755 ISBN-13(EAN): 9781464190759 Издательство: Springer Рейтинг: Цена: 9083.00 р. Наличие на складе: Поставка под заказ.
Описание: Derived from Ben Pierce's popular and acclaimed Genetics: A Conceptual Approach, this streamlined text covers basic transmission, molecular, and population genetics.
Автор: Goodenough Anne Название: Applied Ecology ISBN: 0198723288 ISBN-13(EAN): 9780198723288 Издательство: Oxford Academ Рейтинг: Цена: 9027.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Applied Ecology shows students how an understanding of ecological theory can be used to address the important issues facing ecologists today. Its problem-solving approach reflects the reality of using ecological tools in applied contexts, while highlighting the underlying theories so the link between theory and practice is clear.
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