Post-genomic Approaches in Cancer and Nano Medicine, Kishore R. Sakharkar, Meena K. Sakharkar, Ramesh Chandra
Автор: Kishore R. Sakharkar, Meena K. Sakharkar, Ramesh Chandra Название: Post-genomic Approaches in Drug and Vaccine Development ISBN: 8793102844 ISBN-13(EAN): 9788793102842 Издательство: Taylor&Francis Рейтинг: Цена: 13320.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Over the past decade, genome sequencing projects and associated efforts have facilitated the discovery of several novel disease targets and the approval of several innovative drugs. To further exploit this data for human health and disease, there is a need to understand the genome data itself in detail, discover novel targets, and understand their role in physiological pathways and associated diseases with the aim of translating these discoveries to clinical and preventive medicine. It is equally important to understand the labors and limitations in integrating clinical phenotypes with genomic, transcriptomic, proteomic, and metabolomic approaches. Post-genomic Approaches to Drug and Vaccine Development focuses on some key advances in the field.
Technical topics discussed in the book include: - Drug discovery - Target identification and prioritization - Hypothesis driven multi-target drug design - Genomics in vaccine development - Gene regulatory networks - Vaccine design and development - Prediction of drug side effects in silico
At a ceremony announcing the completion of the first draft of the human genome in 2000, President Bill Clinton declared, "I believe one of the great truths to emerge from this triumphant expedition inside the human genome is that in genetic terms, all human beings, regardless of race, are more than 99.9 percent the same." Yet despite this declaration of unity, biomedical research has focused increasingly on mapping that.1 percent of difference, particularly as it relates to race.
This trend is exemplified by the drug BiDil. Approved by the FDA in 2005 as the first drug with a race-specific indication on its label, BiDil was originally touted as a pathbreaking therapy to treat heart failure in black patients and help underserved populations. Upon closer examination, however, Jonathan Kahn reveals a far more complex story. At the most basic level, BiDil became racial through legal maneuvering and commercial pressure as much as through medical understandings of how the drug worked.
Using BiDil as a central case study, Kahn broadly examines the legal and commercial imperatives driving the expanding role of race in biomedicine, even as scientific advances in genomics could render the issue irrelevant. He surveys the distinct politics informing the use of race in medicine and the very real health disparities caused by racism and social injustice that are now being cast as a mere function of genetic difference. Calling for a more reasoned approach to using race in biomedical research and practice, Kahn asks readers to recognize that, just as genetics is a complex field requiring sensitivity and expertise, so too is race, particularly in the field of biomedicine.
Автор: Joel Weller Название: Genomic Selection in Animals ISBN: 0470960078 ISBN-13(EAN): 9780470960073 Издательство: Wiley Рейтинг: Цена: 20742.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The field of whole genome selection has quickly developed into the breeding methodology of the future. As efforts to map a wide variety of animal genomes have matured and full animal genomes are now available for many animal scientists and breeders are looking to apply these techniques to livestock production.
Автор: Enrico Mihich; Leland Hartwell Название: Genomic Instability and Immortality in Cancer ISBN: 1461374480 ISBN-13(EAN): 9781461374480 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Eighth Annual Pezcoller Symposium held in Trento, Italy, June 17-19, 1996
Автор: Igor Jurisica; Dennis A. Wigle; Bill Wong Название: Cancer Informatics in the Post Genomic Era ISBN: 1441943447 ISBN-13(EAN): 9781441943446 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools for analyzing data in the field of medical information science.
Автор: Ginsburg, Geoffrey S. Название: Genomic and Precision Medicine ISBN: 0128006854 ISBN-13(EAN): 9780128006856 Издательство: Elsevier Science Рейтинг: Цена: 15319.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Genomic and Precision Medicine: Primary Care, Third Edition is an invaluable resource on the state-of-the-art tools, technologies and policy issues that are required to fully realize personalized health care in the area of primary care.
One of the major areas where genomic and personalized medicine is most active is the realm of the primary care practitioner. Risk, family history, personal genomics and pharmacogenomics are becoming increasingly important to the PCP and their patients, and this book discusses the implications as they relate to primary care practitioners.
Presents a comprehensive volume for primary care providers
Provides succinct commentary and key learning points that will assist providers with their local needs for the implementation of genomic and personalized medicine
Includes a current overview on major opportunities for genomic and personalized medicine in practice
Highlights case studies that illustrate the practical use of genomics in the management in patients
Название: Genomic instability and cancer metastasis ISBN: 3319121359 ISBN-13(EAN): 9783319121352 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Genomic Instability and Cancer Metastasis
Автор: Chris Maxwell; Cal Roskelley Название: Genomic Instability and Cancer Metastasis ISBN: 3319352954 ISBN-13(EAN): 9783319352954 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse.
Автор: Jean Champagnat; Monique Denavit-Saubie; Gilles Fo Название: Post-Genomic Perspectives in Modeling and Control of Breathing ISBN: 1489973427 ISBN-13(EAN): 9781489973429 Издательство: Springer Рейтинг: Цена: 30039.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Post Genomic Perspectives in Modeling and Control of Breathing is comprised of the proceedings of the IXth Oxford Conference on Modeling and Control of Breathing, held September 13-16, 2003 in Paris, France.
Автор: Surinder Singh Papiha; Ranjan Deka; Ranajit Chakra Название: Genomic Diversity ISBN: 1461369142 ISBN-13(EAN): 9781461369141 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Symposium on Molecular Anthropology in the 21st Century, held during the 14th International Congress of the Association of Anthropological and Ethnological Sciences, 26 July to 1 August, 1998, in Williamsburg, Virginia, USA
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