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Genomic Instability and Cancer Metastasis, Chris Maxwell; Cal Roskelley


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Автор: Chris Maxwell; Cal Roskelley
Название:  Genomic Instability and Cancer Metastasis
ISBN: 9783319352954
Издательство: Springer
Классификация:

ISBN-10: 3319352954
Обложка/Формат: Paperback
Страницы: 247
Вес: 0.37 кг.
Дата издания: 10.09.2016
Серия: Cancer Metastasis - Biology and Treatment
Язык: English
Размер: 234 x 156 x 14
Основная тема: Biomedicine
Подзаголовок: Mechanisms, Emerging Themes, and Novel Therapeutic Strategies
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse.


Metastasis of Colorectal Cancer

Автор: Beauchemin
Название: Metastasis of Colorectal Cancer
ISBN: 9048188326 ISBN-13(EAN): 9789048188321
Издательство: Springer
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Цена: 28734.00 р.
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Описание: This book covers colon cancer metastasis from fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, and more.

Introduction to Cancer Metastasis

Автор: Ahmad Aamir
Название: Introduction to Cancer Metastasis
ISBN: 0128040033 ISBN-13(EAN): 9780128040034
Издательство: Elsevier Science
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Цена: 20380.00 р.
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Описание: Introduction to Cancer Metastasis provides, in one place, an overview of organ-specific cancer metastasis and the most common sites of cancer metastasis. Through specific chapters on individual primary cancers, their metastasis, and chapters on common metastatic sites, this volume comprehensively informs readers about the broader knowledge base in cancer metastasis. The process of metastasis is particularly responsible for making cancer so lethal. This volume explores both metastasis from sites of origin and common metastatic sites, thus increasing understanding of both perspectives.

Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention

Автор: Wen G. Jiang; R.E. Mansel
Название: Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention
ISBN: 0792363957 ISBN-13(EAN): 9780792363958
Издательство: Springer
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Цена: 34799.00 р.
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Описание: Covers the molecular and cellular aspects of cancer metastasis, and discusses the clinical aspect of micro- and macro-metastases, which result in the death of the majority of patients with cancer. This book attempts to examine the status of the basic scientific and clinical research in the area, and is intended for clinicians and oncologists.

Genomic instability and cancer metastasis

Название: Genomic instability and cancer metastasis
ISBN: 3319121359 ISBN-13(EAN): 9783319121352
Издательство: Springer
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Цена: 22203.00 р.
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Описание: Genomic Instability and Cancer Metastasis

Genomic Instability and Immortality in Cancer

Автор: Enrico Mihich; Leland Hartwell
Название: Genomic Instability and Immortality in Cancer
ISBN: 1461374480 ISBN-13(EAN): 9781461374480
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Proceedings of the Eighth Annual Pezcoller Symposium held in Trento, Italy, June 17-19, 1996

Chromosomal Instability in Cancer Cells

Автор: B. Michael Ghadimi; Thomas Ried
Название: Chromosomal Instability in Cancer Cells
ISBN: 3319349627 ISBN-13(EAN): 9783319349626
Издательство: Springer
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Цена: 11179.00 р.
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Описание: This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer.

Genome Instability

Автор: Marco Muzi-Falconi; Grant W Brown
Название: Genome Instability
ISBN: 1493973053 ISBN-13(EAN): 9781493973057
Издательство: Springer
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Цена: 22359.00 р.
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Описание:

1. The A-like Faker Assay for Measuring Yeast Chromosome III Stability

Carolina A. Novoa, J. Sidney Ang, and Peter C. Stirling

2. The Chromosome Transmission Fidelity Assay for Measuring Chromosome Loss in Yeast

Supipi Duffy and Philip Hieter

3. Measuring Mutation Rates using the Luria-Delbrьck Fluctuation Assay

Gregory I. Lang

4. Molecular Genetic Characterization of Mutagenesis Using a Highly Sensitized Single-Stranded DNA Reporter System in Budding Yeast

Kin Chan

5. Analyzing Genome Rearrangements in Saccharomyces cerevisiae

Anjana Srivatsan, Christopher D. Putnam, and Richard D. Kolodner

6. High Resolution Mapping of Modified DNA Nucleobases using Excision Repair Enzymes

Monica Ransom, D. Suzi Bryan and Jay R. Hesselberth

7. Integrated Microarray-based Tools for Detection of Genomic DNA Damage and Repair Mechanisms

Patrick van Eijk, Yumin Teng, Mark R. Bennet, Katie E. Evans, James R. Powell, Richard M. Webster, and Simon H. Reed

8. Study of UV-induced DNA Repair Factor Recruitment: Kinetics and Dynamics

Sertic S., Roma S., Plevani P., Lazzaro F., and Muzi-Falconi M.

9. Inserting Site-specific DNA Lesions into Whole Genomes

Vincent Pagиs and Robert P Fuchs

10. A qPCR-based Protocol to Quantify DSB Resection

Matteo Ferrari, Shyam Twayana, Federica Marini, and Achille Pellicioli

11. Alkaline Denaturing Southern Blot Analysis to Monitor Double-strand Break Processing

Chiara Vittoria Colombo, Luca Menin, and Michela Clerici

12. Single Molecule Analysis of Resection Tracks

Pablo Huertas and Andrйs Cruz-Garcнa

13. Mapping DNA Breaks by Next-generation Sequencing

Laura Baranello, Fedor Kouzine, Damian Wojtowicz, Kairong Cui, Keji Zhao, Teresa M Przytycka, Giovanni Capranico, and David Levens

14. Genome-wide Profiling of DNA Double-strand Breaks by the BLESS and BLISS Methods

Reza Mirzazadeh, Tomasz Kallas, Magda Bienko, and Nicola Crosetto

15. DNA Replication Profiling using Deep Sequencing

Xanita Saayman, Cristina Ramos-Pйrez, and Grant W Brown

16. Quantitative Bromodeoxyuridine Immunoprecipitation Analyzed by High-Throughput Sequencing (qBrdU-seq or QBU)

Joanna E. Haye-Bertolozzi and Oscar M. Aparicio

17. Strand-specific Analysis of DNA Synthesis and Proteins Association with DNA Replication Forks in Budding Yeast

Chuanhe Yu, Haiyun Gan, and Zhiguo Zhang

18. Analysis of Replicative Polymerase Usage by Ribonucleotide Incorporation

Andrea Keszthelyi, Izumi Miyabe, Katie Ptasińska, Yasukazu Daigaku, Karel Naiman, and Antony M. Carr

19. Dynamic Architecture of Eukaryotic DNA Replication Forks in vivo, Visualized by Electron Microscopy

Ralph Zellweger and Massimo Lopes

20. A Molecular Toolbox to Engineer Site-Specific DNA Replication Perturbation

Nicolai B. Larsen, Ian D. Hickson, and Hocine W. Mankouri

21. Single Cell Gel Electrophoresis for the Detection of Genomic Ribonucleotides

Barbara Kind, Christine Wolf, Kerstin Engel, Alexander Rapp, M. Cristina Cardoso, and Min Ae Lee-Kirsch

22. Measuring the Levels of Ribonucleotides Embedded in Genomic DNA

Meroni A., Nava G.M., Sertic S., Plevani P., Muzi-Falconi M. and Lazzaro F.

23. Mapping Ribonucleotides Incorporated into DNA by Hydrolytic End-Sequencing

Clinton D. Orebaugh, Scott A. Lujan, Adam B. Burkholder, Anders R Clausen, and Thomas A. Kunkel

Electric Cell-Substrate Impedance Sensing  and Cancer Metastasis

Автор: Wen G. Jiang
Название: Electric Cell-Substrate Impedance Sensing and Cancer Metastasis
ISBN: 9400793804 ISBN-13(EAN): 9789400793804
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This book reviews the fundamentals of electric cell-substrate impedance sensing, and recent progress which permits high-throughput automated analyses. Coverage focuses on applications in cell based investigations, particularly in the area of cancer biology.

Cancer Metastasis

Автор: Volker Schirrmacher; Reinhard Schwartz-Albiez
Название: Cancer Metastasis
ISBN: 3540504710 ISBN-13(EAN): 9783540504719
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Proceedings of the 2nd Int. Conference of the Metastasis Research Society of a Satellite Workshop, Heidelberg, September 26-29, 1988

Chromosomal Instability in Cancer Cells

Автор: B. Michael Ghadimi; Thomas Ried
Название: Chromosomal Instability in Cancer Cells
ISBN: 3319202901 ISBN-13(EAN): 9783319202907
Издательство: Springer
Рейтинг:
Цена: 11878.00 р.
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Описание: This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer. Cancer is a disease of the chromosomes, and chromosomal instability in cancer disrupts gene function by either inactivating tumor suppressor genes or activating growth-promoting oncogenes. The chromosomal basis for these aberrations is either translocations, which change the integrity of genes, or abnormal numbers of chromosomes, a condition referred to as aneuploidy, which results in abnormal gene expression levels. Such structural or numerical chromosomal aberrations are specific for distinct tumor entities. The degree of chromosomal instability and the degree of intratumor heterogeneity have profound consequences for disease outcome and for therapeutic stratification.

Oral Cancer Metastasis

Автор: Jeffrey Myers
Название: Oral Cancer Metastasis
ISBN: 1489984763 ISBN-13(EAN): 9781489984760
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Squamous cell carcinoma of the oral cavity (SCCOC) is one of the most prevalent tumors of the head and neck region, but survival rates have not significantly improved. This book summarizes the current status of investigations into SCCOC metastases.

Lung Cancer Metastasis

Автор: Venkateshwar Keshamouni; Douglas Arenberg; Gregory
Название: Lung Cancer Metastasis
ISBN: 148998111X ISBN-13(EAN): 9781489981110
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Lung cancer is the leading cause of cancer-related mortality. Metastatic lung cancer is responsible for more than ninety percent of lung cancer related deaths. However, relatively little progress has been made in understanding the process of lung cancer metastasis. The two main aims of this book are a) to introduce clinical aspects to basic scientists and basic molecular and cellular concepts to clinical investigators, in order to promote collaboration and foster much needed translational research; and b) to introduce new and emerging concepts and approaches in metastasis research to lung cancer research community at large. In this attempt, the book will cover a broad spectrum of subjects ranging from the current trends in the clinical management of the metastatic disease, to the systems biology approach for gaining insights into the mechanisms of metastasis. Some of the subjects covered will include: defining basic hallmarks of a metastatic cell, the concept of tumor stem cells, epithelial-mesenchymal transitions, evasion of immune-surveillance, tumor-stromal interactions, angiogenesis, molecular imaging and biomarker discovery.


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