Автор: Astrid Sigel, Helmut Sigel, Roland K.O. Sigel Название: Lead – Its Effects on Environment and Health ISBN: 3110441071 ISBN-13(EAN): 9783110441079 Издательство: Walter de Gruyter Рейтинг: Цена: 40910.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Volume 17, entitled Lead: Its Effects on Environment and Health of the series Metal Ions in Life Sciences centers on the interrelations between biosystems and lead. The book provides an up-to-date review of the bioinorganic chemistry of this metal and its ions; it covers the biogeochemistry of lead, its use (not only as gasoline additive) and anthropogenic release into the environment, its cycling and speciation in the atmosphere, in waters, soils, and sediments, and also in mammalian organs. The analytical tools to determine and to quantify this toxic element in blood, saliva, urine, hair, etc. are described. The properties of lead(II) complexes formed with amino acids, peptides, proteins (including metallothioneins), nucleobases, nucleotides, nucleic acids, and other ligands of biological relevance are summarized for the solid state and for aqueous solutions as well. All this is important for obtaining a coherent picture on the properties of lead, its effects on plants and toxic actions on mammalian organs. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 17, which are written by 36 internationally recognized experts from 13 nations. The impact of this recently again vibrant research area is manifested in nearly 2000 references, over 50 tables and more than 100 illustrations (half in color). Lead: Its Effects on Environment and Health is an essential resource for scientists working in the wide range from material sciences, inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching.
Elisabeth Behr-Sigel (1907-2005), a convert to Orthodoxy in her early twenties and a central figure of Orthodox theology among Russian emigres in Paris, first began to reflect on the question of women in the priesthood in 1976. Initially supporting the general consensus that priesthood would be impossible for the Orthodox, she came to retract this view, finding a basis for female ordination in women's distinct spiritual charisms. Behr-Sigel later shifted the foundation of her case to personhood, inspired by the work of fellow Orthodox theologian Vladimir Lossky, and arrived at the conclusion that all the Orthodox arguments against the ordination of women were, in fact, heretical at root.
In this volume, Wilson analyzes all of Behr-Sigel's writings about women and the priesthood across the whole sweep of her career, demonstrating the development of her thought on women over the last thirty years of her life. She evaluates her relationship to feminism, Protestantism and movements within Orthodoxy, finally drawing conclusions about this much-contested matter for the ongoing debate in both the East and the West."
Автор: Astrid Sigel, Helmut Sigel, Roland K.O. Sigel Название: Structural and Catalytic Roles of Metal Ions in RNA ISBN: 3110442825 ISBN-13(EAN): 9783110442823 Издательство: Walter de Gruyter Рейтинг: Цена: 16727.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes structural and catalytic roles of metal ions in RNA in an authoritative and timely manner. It deals with diffuse metal ion binding, RNA quadruplexes, the regulation of riboswitches, metal ions and ribozymes, including artificial
Автор: Astrid Sigel, Helmut Sigel, Roland K.O. Sigel Название: Metal Ions in Toxicology: Effects, Interactions, Interdependencies ISBN: 3110442817 ISBN-13(EAN): 9783110442816 Издательство: Walter de Gruyter Рейтинг: Цена: 16727.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: MILS-8 deals with the risk assessment of toxic metal ions and their interdependencies focusing on humans and their organs; thus it carries on the topic of MILS-7 that centered on the environment. This book is of special relevance for researchers in
Автор: Astrid Sigel, Helmut Sigel, Roland K.O. Sigel Название: Organometallics in Environment and Toxicology ISBN: 3110442809 ISBN-13(EAN): 9783110442809 Издательство: Walter de Gruyter Цена: 16727.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Volume 7, devoted to the vital and rapidly expanding research area around metal-carbon bonds (see also MILS-6), focuses on the environment. With more than 2500 references, 35 tables, and nearly 50 illustrations, many of these in color, it is an essential resource for scientists working in the wide range from organometallic chemistry, inorganic biochemistry, environmental toxicology all the way through to physiology and medicine. In 14 stimulating chapters, written by 29 internationally recognized experts, Organometallics in Environment and Toxicology highlights in an authoritative and timely manner environmental cycles of elements involving organometal(loid) compounds as well as the analytical determination of such species. This book examines methane formation involving the nickel coenzyme F430, as well as the organometal(loid) compounds formed by tin, lead, arsenic, antimony, bismuth, selenium, tellurium, and mercury. In addition, it deals with the environmental bioindication, biomonitoring, and bioremediation of organometal(loid)s, and it terminates with methylated metal(loid) species occurring in humans by evaluating assumed and proven health effects caused by these compounds.
Автор: Astrid Sigel, Helmut Sigel, Roland K.O. Sigel Название: Metal-Carbon Bonds in Enzymes and Cofactors ISBN: 3110442795 ISBN-13(EAN): 9783110442793 Издательство: Walter de Gruyter Рейтинг: Цена: 16727.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently appreciated. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds ar
Автор: Astrid Sigel, Helmut Sigel, Roland K.O. Sigel Название: Metallothioneins and Related Chelators ISBN: 3110442787 ISBN-13(EAN): 9783110442786 Издательство: Walter de Gruyter Рейтинг: Цена: 16727.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These sulfur-rich chelators, being important in metal ion homeostasis, find increasing attention. MILS-5, written by 30 internationally recognized experts, focuses on this hot topic. This book is an essential resource for scientists working in the w
Автор: Beanie Sigel, Juma Sampson Название: Loyalty and Deceit ISBN: 0984006036 ISBN-13(EAN): 9780984006038 Издательство: Неизвестно Цена: 2069.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Sigel Astrid, Sigel Helmut, Freisinger Eva Название: Metallo-Drugs: Development and Action of Anticancer Agents ISBN: 3110469847 ISBN-13(EAN): 9783110469844 Издательство: Walter de Gruyter Цена: 76442.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Volume 18, entitled Metallo-Drugs: Development and Action of Anticancer Agents of the series Metal Ions in Life Sciences centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching.
Описание: Elisabeth Behr-Sigel (1907-2005), a convert to Orthodoxy in her early twenties and a central figure of Orthodox theology among Russian emigres in Paris, first began to reflect on the question of women in the priesthood in 1976. Initially supporting the general consensus that priesthood would be impossible for the Orthodox, she came to retract this view, finding a basis for female ordination in women's distinct spiritual charisms. Behr-Sigel later shifted the foundation of her case to personhood, inspired by the work of fellow Orthodox theologian Vladimir Lossky, and arrived at the conclusion that all the Orthodox arguments against the ordination of women were, in fact, heretical at root. In this volume, Wilson analyzes all of Behr-Sigel's writings about women and the priesthood across the whole sweep of her career, demonstrating the development of her thought on women over the last thirty years of her life. She evaluates her relationship to feminism, Protestantism and movements within Orthodoxy, finally drawing conclusions about this much-contested matter for the ongoing debate in both the East and the West.
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