Cytokines: Roles and Therapeutic Implications, Erik Krueger

Автор: Ghezzi Pietro
Название: Tissue Protective Cytokines
ISBN: 1627033076 ISBN-13(EAN): 9781627033077
Издательство: Springer
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Описание: Thorough and informative, this Methods in Molecular Biology(t) book presents key models used to characterize the tissue-protective actions of cytokines. Offers lists of materials and reagents, step-by-step laboratory protocols, troubleshooting tips and pitfalls.

Автор: Pietro Ghezzi; Anthony Cerami
Название: Tissue-Protective Cytokines
ISBN: 1493962442 ISBN-13(EAN): 9781493962440
Издательство: Springer
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Цена: 20263.00 р.
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Описание: Thorough and informative, this Methods in Molecular Biology (TM) book presents key models used to characterize the tissue-protective actions of cytokines. Offers lists of materials and reagents, step-by-step laboratory protocols, troubleshooting tips and pitfalls.

Автор: Alain Beschin; Werner E. G. M?ller
Название: Invertebrate Cytokines and the Phylogeny of Immunity
ISBN: 3642622364 ISBN-13(EAN): 9783642622366
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Based on the assumption that invertebrates as well as vertebrates possess factors regulating hematopoiesis, response to infection or wounding, studies dealing with the evolution of immunity have focused on the isolation and characterization of putative cytokine-related molecules from invertebrates.

Автор: J. Westwick; I.J.D. Lindley; S.L. Kunkel
Название: Chemotactic Cytokines
ISBN: 1468460110 ISBN-13(EAN): 9781468460117
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Proceedings of the Second International Symposium on Chemotactic Cytokines, held in London, UK, June 25--26, 1990

Автор: Echard, Arnaud
Название: Cytokinesis,137
ISBN: 012809673X ISBN-13(EAN): 9780128096734
Издательство: Elsevier Science
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Цена: 21222.00 р.
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Описание:

Cytokinesis, the latest volume in the Methods in Cell Biology series, looks at the latest advances in cytokinesis. Edited by leaders in the field, this volume presents proven, state-of-art techniques, along with relevant historical background and theory, to aid researchers in efficient design and effective implementation of experimental methodologies.

Автор: Jawahar L. Mehta; Pankaj Mathur; Naranjan S. Dhall
Название: Biochemical Basis and Therapeutic Implications of Angiogenesis
ISBN: 3319611143 ISBN-13(EAN): 9783319611143
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Leading authorities on the biochemistry of this complex physiological process explain its critical role in human growth and development as well as the pathogenesis of cancer, heart disease, and other morbidities. The book fully updates the current literature.

Автор: Cordero
Название: Inflammasomes: Clinical and Therapeutic Implications
ISBN: 3319893890 ISBN-13(EAN): 9783319893891
Издательство: Springer
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Цена: 20962.00 р.
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Описание: The inflammasome is a protein complex composed of an intracellular sensor—typically a Nod-like receptor (NLR), the precursor procaspase-1, and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrates, IL-1? and IL-18. The inflammasome has been implicated numerous diseases, and blockade of inflammasome-derived IL-1? has beneficial effects on several of these diseases. Different books have been edited about the biology of inflammasomes and about methods to study, however, the implication of this complex in the different diseases and pathological conditions show the need of a book about the clinical implications and therapeutic options. This project will show the context where inflammasomes are being studied and the molecular implications in the medical and clinical contexts. Other important topic of the inflammasomes will be the development of pharmacological inhibitors in order to improve new clinical applications. In this sense, we can find new drugs with inhibitory effects or old drugs with an inhibitory potential effect. There is a need for re-establishing the real benefits of the inflammasome inhibitions in pathological situations and the management of the differents diseases where inflammasomes are implicated.

Автор: Andreas Habenicht
Название: Growth Factors, Differentiation Factors, and Cytokines
ISBN: 3642748589 ISBN-13(EAN): 9783642748585
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Leading international experts contribute to this selection of reviews covering the merging fields of growth factors, differentiation factors, and cytokines.

Автор: Vijay K. Kuchroo; Nora Sarvetnick; David A. Hafler
Название: Cytokines and Autoimmune Diseases
ISBN: 0896038564 ISBN-13(EAN): 9780896038561
Издательство: Springer
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Описание: Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases.

Автор: Mario D. Cordero; El?sabet Alcocer-G?mez
Название: Inflammasomes: Clinical and Therapeutic Implications
ISBN: 3030077586 ISBN-13(EAN): 9783030077587
Издательство: Springer
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Цена: 20962.00 р.
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Описание: The inflammasome is a protein complex composed of an intracellular sensor—typically a Nod-like receptor (NLR), the precursor procaspase-1, and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrates, IL-1? and IL-18. The inflammasome has been implicated numerous diseases, and blockade of inflammasome-derived IL-1? has beneficial effects on several of these diseases. Different books have been edited about the biology of inflammasomes and about methods to study, however, the implication of this complex in the different diseases and pathological conditions show the need of a book about the clinical implications and therapeutic options. This project will show the context where inflammasomes are being studied and the molecular implications in the medical and clinical contexts. Other important topic of the inflammasomes will be the development of pharmacological inhibitors in order to improve new clinical applications. In this sense, we can find new drugs with inhibitory effects or old drugs with an inhibitory potential effect. There is a need for re-establishing the real benefits of the inflammasome inhibitions in pathological situations and the management of the differents diseases where inflammasomes are implicated.

Автор: Nikolaos Labrou
Название: Therapeutic Enzymes: Function and Clinical Implications
ISBN: 9811377081 ISBN-13(EAN): 9789811377082
Издательство: Springer
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Цена: 21661.00 р.
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Описание: Therapeutic enzymes exhibit fascinating features and opportunities, and represent a significant and promising subcategory of modern biopharmaceuticals for the treatment of several severe diseases. Research and drug developments efforts and the advancements in biotechnology over the past twenty years have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of both rare and common disorders. The introduction and regulatory approval of twenty different recombinant enzymes has enabled effective enzyme-replacement therapy. This volume aims to overview these therapeutic enzymes, focusing in particular on more recently approved enzymes produced by recombinant DNA technology. This volume is composed of four sections. Section 1 provides an overview of the production process and biochemical characterization of therapeutic enzymes, while Section 2 focuses upon the engineering strategies and delivery methods of therapeutic enzymes. Section 3 highlights the clinical applications of approved therapeutic enzymes, including aspects on their structure, indications and mechanisms of action. Together with information on these mechanisms, safety and immunogenicity issues and various adverse events of the recombinant enzymes used for therapy are discussed. Section 4, provides discussion on the prospective and future developments of new therapeutic enzymes. This book is aimed at academics, researchers and students undertaking advanced undergraduate/postgraduate programs in the biopharmaceutical/biotechnology area who wish to gain a comprehensive understanding of enzyme-based therapeutic molecules.