Описание: Describes methods for the production of viral and non-viral gene transfer vectors, as well as protocols for critical applications in stem cell biology, cancer, diabetes, HIV and tissue engineering.
Описание: The field of gene therapy has undergone remarkable advances, promising to impact human healthcare in the 21st century. This book provides methods for the processing and characterization of viral and non-viral gene transfer vectors, as well as promising approaches to design vectors for efficient, targeted and regulated gene delivery and expression.
Автор: A. Pullman; Joshua Jortner Название: Nucleic Acids: The Vectors of Life ISBN: 940097227X ISBN-13(EAN): 9789400972278 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Sixteenth Jerusalem Symposium on Quantum Chemistry and Biochemistry held in Jerusalem, Israel, May 2-5, 1983
Автор: Merten Название: Viral Vectors for Gene Therapy ISBN: 161779094X ISBN-13(EAN): 9781617790942 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The huge potential for gene therapy to cure a wide range of diseases has led to high expectations and a great increase in research efforts in this area, particularly in the study of delivery via viral vectors, widely considered to be more efficient than DNA transfection. In Viral Vectors for Gene Therapy: Methods and Protocols, experts in the field present a collection of their knowledge and experience featuring methodologies that involve virus production, transferring protocols, and evaluating the efficacy of gene products. While thoroughly covering the most popular viral vector systems of adenovirus, retrovirus, and adeno-associated virus, this detailed volume also explores less common viral vector systems such as baculovirus, herpes virus, and measles virus, the growing interest in which is creating a considerable demand for large scale manufacturing and purification procedures. Written in the highly successful Methods in Molecular Biology™ series format, many chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and vital tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Viral Vectors for Gene Therapy: Methods and Protocols provides basic principles accessible to scientists from a wide variety of backgrounds for the development of gene therapy viral products that are safe and effective.
Описание: When organisms are deliberately or accidentally introduced into a new ecosystem a biological invasion may take place. These so-called ‘invasive species’ may establish, spread and ecologically alter the invaded community. Biological invasions by animals, plants, pathogens or vectors are one of the greatest environmental and economic threats and, along with habitat destruction, a leading cause of global biodiversity loss. In this book, more than 50 worldwide invasion scientists cover our current understanding of biological invasions, its impacts, patterns and mechanisms in both aquatic and terrestrial systems.
Описание: This book covers the fundamental topics and tools involved in conceptualizing vectors and their applications in the fields of engineering and sciences in a lucid manner. The text includes important topics such as transformation groups, groups of isometries and the Euler group, with applications to rigid displacements.
Автор: Fredric P. Manfredsson; Matthew J. Benskey Название: Viral Vectors for Gene Therapy ISBN: 1493990640 ISBN-13(EAN): 9781493990641 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This volume discusses protocols, ranging from vector production to delivery methods, used to execute gene therapy applications. Chapters are divided into four parts, and cover topics such as design, construction, and application of transcription activation-like effectors; multi-modal production of adeno-associated virus; construction of oncolytic herpes simplex virus; AAV-mediated gene delivery to the mouse liver; and intrathecal delivery of gene therapeutics by direct lumbar puncture in mice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and authoritative, Viral Vectors for Gene Therapy: Methods and Protocols is a valuable resource for researchers, clinicians, and students looking to utilize viral vectors in gene therapy experiments.
Автор: Jacques Derek Charlwood Название: The Ecology of Malaria Vectors ISBN: 0367248484 ISBN-13(EAN): 9780367248482 Издательство: Taylor&Francis Рейтинг: Цена: 11482.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This practical book covers all aspects of the biology of malaria vectors, with notes on the vectors of dengue. It is designed to fill the gap between very specialised texts and undergraduate books on general disease vectors, and is ideal as a textbook for postgraduate courses in entomology and mosquito vectors of disease.
Автор: Haber, Morey J. Hibbert, Brad Название: Asset attack vectors ISBN: 1484236262 ISBN-13(EAN): 9781484236260 Издательство: Springer Рейтинг: Цена: 6288.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Michael J. Castle Название: Adeno-Associated Virus Vectors ISBN: 1493991388 ISBN-13(EAN): 9781493991389 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides a complete and timely guide to the use of adeno-associated virus (AAV) vectors for genetic manipulation of mammalian tissues. Beginning with methods for the design and characterization of AAV vectors, the book continues with protocols for AAV delivery to various components of the central nervous system, to a number of sensory systems, and to a broad range of other tissues. Novel techniques such as ultrasound-targeted delivery to the brain, subpial delivery to the spinal cord, and subILM delivery to the retina are accompanied by chapters that provide an overview and comparison of current methods for AAV delivery to tissues such as brain, heart, liver, and lung. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible step-by-step laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.
Authoritative and comprehensive, Adeno-Associated Virus Vectors: Design and Delivery aims to enhance the utility of AAV vectors for targeted gene transfer to living animals and continue the ongoing development of novel AAV-based gene therapies for human disease.
Автор: Kenneth Palmer; Yuri Gleba Название: Plant Viral Vectors ISBN: 3642408281 ISBN-13(EAN): 9783642408281 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This wide-ranging review shows how far our understanding of plant viral vectors has come, with experts in `vectorology` contributing chapters on their work applying the science to cutting-edge techniques in genetics, nanotechnology, and other fields.
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