Cancer and Zebrafish: Mechanisms, Techniques, and Models, Langenau David M.

Автор: David M. Langenau
Название: Cancer and Zebrafish
ISBN: 3319306529 ISBN-13(EAN): 9783319306520
Издательство: Springer
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Цена: 28734.00 р.
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Описание: This volume focuses on defining the unique attributes of using the zebrafish cancer model for discovering important pathways and potential drug targets for the treatment of human cancers.

Автор: Gerlai, Robert T.
Название: Behavioral And Neural Genetics Of Zebrafish
ISBN: 0128175281 ISBN-13(EAN): 9780128175286
Издательство: Elsevier Science
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Цена: 23075.00 р.
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Описание:

The past decade has seen a rapid accumulation of knowledge on the behavioral characteristics of zebrafish, and their use in increased investigation into the neurobiological basis of behavior. This simple vertebrate represents an ideal compromise between system complexity and practical simplicity, with its mammalian sequence homology, fecundity, transparent embryology, and conveniently small size. Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and the most current concepts pertinent to their neurobehavioral genetics. Discussing its natural behavior, motor function, and learning and memory, it focuses on the fry and adult zebrafish and features a comprehensive account of modern genetic and neural methods adapted to or specifically developed for Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish will be presented, as well as a section on bioinformatics and big-data related questions. Focusing on this excellent translational tool, this book examines a species with which investigators may model and analyze even such complex human diseases as those associated with brain dysfunction.

Автор: Mario F. Wulliman; Barbara Rupp; Heinrich Reichert
Название: Neuroanatomy of the Zebrafish Brain
ISBN: 3034898525 ISBN-13(EAN): 9783034898522
Издательство: Springer
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Цена: 12577.00 р.
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Автор: Hiromi Hirata; Atsuo Iida
Название: Zebrafish, Medaka, and Other Small Fishes
ISBN: 9811318786 ISBN-13(EAN): 9789811318788
Издательство: Springer
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Цена: 25155.00 р.
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Описание: This book provides cutting-edge studies and technologies using small fishes, including zebrafish, medaka, and other fishes as new model animals for molecular biology, developmental biology, and medicine. It also introduces eccentric fish models that are pioneering new frontiers of biology. Zebrafish and medaka have been developed as lower vertebrate model organisms because these small fish are easy to raise in the laboratory and are useful for the live imaging of the morphology and activity of cells and tissues in intact animals. By virtue of those specific advantages, fish studies have demonstrated the common features of vertebrates and raised further questions toward understanding the mystery of life. The book consists of four parts: “Development and Cell Biology”, “Homeostasis and Reproduction”, “Clinical Models”, and “Eccentric Fish”. Together they describes the core area of small fish study – often considered mere zoology but which is actually proving to be the universal basis of life. Written by leading scientists, the book helps readers to understand small fishes, inspires scientists to utilize small fishes in their studies, and encourages anyone who wants to participate in the large and fantastic world of small fish.

Автор: Allan V. Kalueff; Jonathan M. Cachat
Название: Zebrafish Models in Neurobehavioral Research
ISBN: 1493959220 ISBN-13(EAN): 9781493959228
Издательство: Springer
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Цена: 19564.00 р.
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Описание: Animal models have traditionally played a crucial role in improving our understanding of brain pathogenesis. Zebrafish (Danio rerio) have generated considerable discoveries in the areas of genetics, embryology, endocrinology, and neuroscience. Zebrafish Models in Neurobehavioral Research emphasizes the growing importance of zebrafish in neurobehavioral research and portrays an extensive, thorough perspective on the emergence of zebrafish as robust and translational models. Written by leading international experts, the book covers major topics ranging from stress to learned recognition of environment, encompassing a wide spectrum of the utility of zebrafish within neurobiological disciplines. The chapters provide authoritative reviews of many zebrafish paradigms commonly used in the field today. This book will be a useful guide for zebrafish researchers, and will complement another related book from the popular Neuromethods series, Zebrafish Neurobehavioral Protocols. Comprehensive and up-to-date, Zebrafish Models in Neurobehavioral Research serves as an ideal resource for scientists new to the field as well as for established researchers seeking valuable insight into the growing utility of zebrafish in neuroscience.

Автор: Detrich, III, H. William
Название: The Zebrafish: Disease Models and Chemical Screens,105
ISBN: 0128034734 ISBN-13(EAN): 9780128034736
Издательство: Elsevier Science
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Цена: 22570.00 р.
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Описание: The Zebrafish: Disease Models and Chemical Screens, Fourth Edition, the latest volume in the Methods in Cell Biology series, looks at methods for analyzing genetics, genomics, and transcriptomics of zebrafish. Chapters cover such topics as gene-trap mutagenesis, genetic screens for mutations, gene editing in zebrafish, homologous gene targeting, genome-wide RNA tomography, developmental epigenetics, and the zebrafish interactome. * Covers sections on model systems and functional studies, imaging-based approaches, and emerging studies* Includes chapters written by experts in the field* Contains cutting-edge material on the topics discussed

Автор: Dr. Thomas Mueller
Название: Atlas of Early Zebrafish Brain Development
ISBN: 0124186696 ISBN-13(EAN): 9780124186699
Издательство: Elsevier Science
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Цена: 15917.00 р.
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Описание: . Atlas of Early Zebrafish Brain Development: A Tool for Molecular Neurogenetics, Second Edition, remains the only neuroanatomical expression atlas of important genetic and immunohistochemical markers of this vertebrate model system. . It represents a key reference and interpretation matrix for analyzing expression domains of genes involved in Zebrafish brain development and neurogenesis, and serves as a continuing milestone in this research area. . This updated volume provides in-situ hybridized and immunostained preparations of complete series of brain sections, revealing markers of the fundamental stages in the life history of neuronal cells in very high quality preparations and photographic plates. Specific additions to this edition include documentation on the distribution of neurons expressing GABA, dopamine and serotonin, material on the basal ganglia, hypothalamus, and the caudal, segmented part of the diencephalon, new theories on the early organization of the telencephalon and thalamus, and integration of a comparative perspective on the mid- and hindbrain.

Автор: Hiromi Hirata; Atsuo Iida
Название: Zebrafish, Medaka, and Other Small Fishes
ISBN: 9811346976 ISBN-13(EAN): 9789811346972
Издательство: Springer
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Цена: 16070.00 р.
Наличие на складе: Поставка под заказ.

Описание: This book provides cutting-edge studies and technologies using small fishes, including zebrafish, medaka, and other fishes as new model animals for molecular biology, developmental biology, and medicine. It also introduces eccentric fish models that are pioneering new frontiers of biology.Zebrafish and medaka have been developed as lower vertebrate model organisms because these small fish are easy to raise in the laboratory and are useful for the live imaging of the morphology and activity of cells and tissues in intact animals. By virtue of those specific advantages, fish studies have demonstrated the common features of vertebrates and raised further questions toward understanding the mystery of life.The book consists of four parts: “Development and Cell Biology”, “Homeostasis and Reproduction”, “Clinical Models”, and “Eccentric Fish”. Together they describes the core area of small fish study – often considered mere zoology but which is actually proving to be the universal basis of life.Written by leading scientists, the book helps readers to understand small fishes, inspires scientists to utilize small fishes in their studies, and encourages anyone who wants to participate in the large and fantastic world of small fish.

Автор: Detrich, III, H. William
Название: The Zebrafish: Genetics, Genomics, and Transcriptomics,135
ISBN: 0128034742 ISBN-13(EAN): 9780128034743
Издательство: Elsevier Science
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Цена: 21222.00 р.
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Описание: "

The Zebrafish: Genetics, Genomics, and Transcriptomics, Fourth Edition, "is the latest volume in the "Methods in Cell Biology "series that looks at methods for the analysis of genetics, genomics, and transcriptomics of Zebrafish.

Chapters cover such topics as gene-trap mutagenesis, genetic Screens for mutations, gene editing in zebrafish, homologous gene targeting, genome-wide RNA tomography, and developmental epigenetics and the zebrafish interactome.
Covers sections on model systems and functional studies, imaging-based approaches, and emerging studiesPresents chapters written by experts in the fieldContains cutting-edge material on the topic

Автор: Itia Amandine Favre?Bulle
Название: Imaging, Manipulation and Optogenetics in Zebrafish
ISBN: 3030071642 ISBN-13(EAN): 9783030071646
Издательство: Springer
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Цена: 15372.00 р.
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Описание: The work described here investigates the advantages and limitations of using laser light for the deep in-vivo illumination and micromanipulation of the neuronal system in zebrafish. To do so, it combines and develops novel optical methods such as optogenetics, light sheet microscopy and optical micromanipulation. It also demonstrates, for the first time, that directional and focused laser beams can successfully be used to target large objects at considerable depth in a living organism to exert purely optical force – in this case on otoliths (ear stones) – and create fictive vestibular stimuli in a stationary animal. The behavioural study and simultaneous imaging of the whole brain reveal the location of the brain cells specific to each ear stone. Elucidating these fundamental neural processes holds substantial value for basic neuroscience researchers, who still have only a vague grasp of how brain circuits mediate perception. As such, it represents highly innovative research that has already led to high-impact publications and is now being intensively pursued.