The Epithelial-To Mesenchymal Transition: Methods and Protocols, Campbell Kyra, Theveneau Eric
Автор: Itzhak D. Goldberg; Eliot M. Rosen Название: Epithelial—Mesenchymal Interactions in Cancer ISBN: 3034898932 ISBN-13(EAN): 9783034898935 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Joachim R. Wolff; Jobst Sievers; Martin Berry Название: Mesenchymal-Epithelial Interactions in Neural Development ISBN: 3642718396 ISBN-13(EAN): 9783642718397 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop on Mesenchymal-Epithelial Interaction in Neural Development held at West-Berlin,FRG, March 17-21, 1986
Автор: Scott H. Randell; M. Leslie Fulcher Название: Epithelial Cell Culture Protocols ISBN: 1493956795 ISBN-13(EAN): 9781493956791 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In its 2nd edition, this Methods in Molecular Biology (TM) volume provides a cross section of up-to-date culture protocols for the most studied cell systems and supporting technologies. Includes materials lists, step-by-step protocols and troubleshooting tips.
Автор: Lucas G. Chase; Mohan C Vemuri Название: Mesenchymal Stem Cell Therapy ISBN: 1627039147 ISBN-13(EAN): 9781627039147 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.
Описание: Written by researchers from around the globe, this book reviews the properties of Mesenchymal stem cells, summarizes the current state of knowledge in stem cell research, reports on cutting-edge methods and protocols and offers insight on effective therapies.
Автор: Mariana Garcia Название: Mesenchymal Stromal Cells as Tumor Stromal Modulators ISBN: 0128031026 ISBN-13(EAN): 9780128031025 Издательство: Elsevier Science Рейтинг: Цена: 18696.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mesenchymal stromal/ stem cells (MSCs) represent a heterogeneous cell population with immunomodulating, tissue repairing, differentiating, migratory and angiogenic abilities, making them important tools for clinical and translational research. An understanding of the role of MSCs in modulating tumor growth provides a glimpse into their role in non-pathological tissue remodeling and potential regenerative tissue therapies. Mesenchymal Stromal Cells as Tumor Stromal Modulators is a comprehensive source for the understanding of the role of MSCs as ubiquitous connective tissue cell components, which may have both direct and indirect effects on the tumor microenvironment and potential for regenerative therapeutics for various diseases. Using cancer as a model disease, this book explores the transformative role MSCs play in the recruitment of disease cells, cell repair and immunological defenses.
Автор: Birgit Weyand; Massimo Dominici; Ralf Hass; Roland Название: Mesenchymal Stem Cells - Basics and Clinical Application II ISBN: 3642379435 ISBN-13(EAN): 9783642379437 Издательство: Springer Рейтинг: Цена: 39130.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Engineered MSCs from Patient-Specific iPS Cells, by Irina Eberle, Mohsen Moslem, Reinhard Henschler, Tobias Cantz
Fate of Intravenously Injected Mesenchymal Stem Cells and Significance for Clinical Application, by Beate Wagner, Reinhard Henschler
The Implications of Stem Cell Applications for Diseases of the Respiratory System, by Mei Ling Lim, Philipp Jungebluth, Paolo Macchiarini
Potential of Mesenchymal Stem Cell Applications in Plastic and Reconstructive Surgery, by Birgit Weyand, Peter M. Vogt
General Principles for the Regeneration of Bone and Cartilage, by Michael Jagodzinski, C. Haasper
Adult Mesenchymal Stem Cells Explored in the Dental Field, by K. M. Fawzy El-Sayed, C. D rfer, F. F ndrich, F. Gieseler, M. H. Moustafa, H. Ungefroren
Mesenchymal Stem Cell Therapy and Lung Diseases, by Khondoker M. Akram, Sohel Samad, Monica Spiteri, Nicholas R. Forsyth
Mesenchymal Stem Cells as Cellular Immunotherapeutics in Allogeneic Hematopoietic Stem Cell Transplantation, by Claudia Papewalis, Daniela Topolar, Barbara G tz, Stefan Sch nberger, Dagmar Dilloo
New Cell-Based Therapy Paradigm: Induction of Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells into Pro-Inflammatory MSC1 and Anti-inflammatory MSC2 Phenotypes, by Aline M. Betancourt
Interactions Between Mesenchymal Stem Cells and Dendritic Cells, by Grazia Maria Spaggiari, Lorenzo Moretta
MSC and Tumors: Homing, Differentiation, and Secretion Influence Therapeutic Potential, by Naomi D'souza, Jorge Sans Burns, Giulia Grisendi, Olivia Candini, Elena Veronesi, Serena Piccinno, Edwin M. Horwitz, Paolo Paolucci, Pierfranco Conte, Massimo Dominici
Sources of Mesenchymal Stem Cells: Current and Future Clinical Use, by Michela Pozzobon, Martina Piccoli, Paolo De Coppi
Role of the EU Framework in Regulation of Stem Cell-Based Products, by Giovanni Migliaccio, Cristina Pintus
Автор: Birgit Weyand; Massimo Dominici; Ralf Hass; Roland Название: Mesenchymal Stem Cells - Basics and Clinical Application I ISBN: 3642356702 ISBN-13(EAN): 9783642356704 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Prospective Isolation and Characterization of Human Bone Marrow-Derived MSCs, by A. Harichandan, K. Sivasubramaniyan, H.-J. B hring Urine as a Source of Stem Cells, by Christina Benda, Ting Zhou, Xianming Wang, Weihua Tian, Johannes Grillari, Hung-Fat Tse, Regina Grillari-Voglauer, Duanqing Pei, Miguel A. Esteban Expansion of Mesenchymal Stem/Stromal Cells under Xenogenic-Free Culture Conditions, by Sven Kinzebach, Karen Bieback Adipose-Derived Mesenchymal Stem Cells: Biology and Potential Applications, by Danielle Minteer, Kacey G Marra, J Peter Rubin Potential for Osteogenic and Chondrogenic Differentiation of MSC, by Antonina Lavrentieva, Tim Hatlapatka, Anne Neumann, Birgit Weyand, Cornelia Kasper Potential for Neural Differentiation of Mesenchymal Stem Cells, by Letizia Ferroni, Chiara Gardin, Ilaria Tocco, Roberta Epis, Alessandro Casadei, Vincenzo Vindigni, Giuseppe Mucci, Barbara Zavan Migratory Properties of Mesenchymal Stem Cells, by Thomas Dittmar, Frank Entschladen Dissecting Paracrine Effectors for Mesenchymal Stem Cells, by Stefania Bruno, Federica Collino, Ciro Tetta, Giovanni Camussi Proteomics Approaches in the Identification of Molecular Signatures of Mesenchymal Stem Cells, by Yin Xiao, Jiezhong Chen Does the Adult Stroma Contain Stem Cells?, by Richard Sch fer
Автор: Darwin J. Prockop; Donald G. Phinney; Bruce A. Bun Название: Mesenchymal Stem Cells ISBN: 1617377678 ISBN-13(EAN): 9781617377679 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For over forty years, mesenchymal stem cells (MSCs) have been scrutinized and studied, garnering much attention due to their broad therapeutic efficacy. In this essential book, leaders in the field were assembled to contribute detailed methodologies for the isolation and characterization of human and rodent MSCs.
Автор: Massimiliano Gnecchi Название: Mesenchymal Stem Cells ISBN: 1493980858 ISBN-13(EAN): 9781493980857 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Поставка под заказ.
Автор: Malemud Charles J., Alsberg Eben Название: Mesenchymal Stem Cells and Immunomodulation ISBN: 3319835734 ISBN-13(EAN): 9783319835730 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Overview.- Part I: Autoimmune Diseases.- Chapter 1: Altering Immune-Mediated Inflammatory Responses With Stem Cells.- Chapter 2: Rheumatoid Arthritis.- Chapter 3: Systemic Lupus Erythematosus.- Chapter 4: Crohn's Diseases.- Chapter 5: Multiple Sclerosis.- Part II: Cancer.- Chapter 6: Eliminating Cancer with Stem Cells by Correcting Dysfunctional Immunity.- Chapter 7: Asymmetric Cell Division of Stem and Progenitor Cells in Homeostasis and Cancer.- Chapter 8: Stem Cells: Modifiers of Defective Transcription Factor Activity Induced by Cytokines in Cancer.- Chapter 9: Therapeutic Targeting of Prostate Cancer with Stem Cells.- Chapter 10: The Efficacy of Stem Cells in Experimental Animal Models of Leukemia.- Part III: Cardiovascular Disease.- Chapter 11: Immune-Mediated Inflammation in Heart Disease.- Chapter 12: Stem Cell Therapy: Dampening Immune-Mediated Inflammation in Coronary Artery Disease.- Part IV: Neurodegenerative Diseases.- Chapter 13: Similarities and Differences in Stem Cells Between Cancer, Normal and Injured Brain.- Chapter 2: Defective Immune Modulation in Parkinson's Disease: Potential Role of Stem Cells.- Part V: Immune Modulation In Pregnancy and Parturition.- Chapter 14: Role of Immune-Mediated Inflammation in Pregnancy.- Chapter 15: Cytokine-Mediated Inflammation in Pre-Term Labor.- Chapter 16: Using Stem Cells to Prevent Inflammation-Induced Pre-Term Labor.
Автор: Peiman, Hematti Название: Mesenchymal Stromal Cells ISBN: 0128028262 ISBN-13(EAN): 9780128028261 Издательство: Elsevier Science Рейтинг: Цена: 14654.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial. Written by professionals with hands-on experience in bringing MSC therapies to the clinic, and building on the biology and mechanisms of action, this unique book covers the development and production of clinical-grade products that are suitable for use in humans. From design of a cell production facility, to obtaining regulatory approval and reimbursement issues, it is a useful guide for researchers and administrators across biomedical research.
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