Multiplex Biomarker Techniques: Methods and Applications, Guest Paul C.
Автор: Paul C. Guest Название: Multiplex Biomarker Techniques ISBN: 1493967290 ISBN-13(EAN): 9781493967292 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed book arrives as there is an increasing need for multiplex biomarker readouts for improved clinical management and to support the development of new drugs by pharmaceutical companies, due to continuous technical developments and new insights into the high complexity of many diseases.
Автор: Feng Wang Название: Biomarker Methods in Drug Discovery and Development ISBN: 1617379255 ISBN-13(EAN): 9781617379253 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, expert researchers provide a tool box for those who have a general interest in biomarker research and for those currently specializing in certain technologies but desiring an understanding of other available methodologies.
Автор: Roberto Scatena Название: Advances in Cancer Biomarkers ISBN: 9402404201 ISBN-13(EAN): 9789402404203 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Prelims.- I Generality.- II Tumor markers-a critical revision.- Enzymes.- Hormones.- Oncofetal proteins.- Cytokeratins.- Carbohydrate markers.- Blood group antigens.- Genetic markers.- Various protein markers.- III Perspectives.- The role of Circulating tumor Cells as tumor markers.- Index.
Название: Toxicologic Biomarkers ISBN: 0367453703 ISBN-13(EAN): 9780367453701 Издательство: Taylor&Francis Рейтинг: Цена: 9492.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Responding to the explosion of advances in the use of biomarkers to efficiently, rapidly, and economically evaluate the health effects of chemical entities, this authoritative reference provides a detailed overview of the theory, development, and practical application of biomarkers in the toxicological, environmental, forensic, and pharmaceutical s
Описание: This book describes current research on disease biomarkers, including oncofetal molecules in cancer prediction and treatment, evolving development in cancer biology at the cellular and molecular levels and understanding of new classes of molecules in diseases.
Автор: Lambert Holly Название: Biomarkers in Drug Discovery and Disease Diagnosis ISBN: 1632428350 ISBN-13(EAN): 9781632428356 Издательство: Неизвестно Рейтинг: Цена: 23335.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Kewal K. Jain Название: The Handbook of Biomarkers ISBN: 1627038361 ISBN-13(EAN): 9781627038362 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Of the thousands of biomarkers that are currently being discovered, relatively few are being validated for further applications, and the potential of a biomarker can be quite difficult to evaluate. To aid in this imperative research, Dr. Kewal K. Jain’s Handbook of Biomarkers thoroughly describes many different types of biomarkers and their discovery using various "-omics" technologies, such as proteomics and metabolomics, along with the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials. With biomarkers described first according to technologies and then according to various diseases, this detailed book features the key correlations between diseases and classifications of biomarkers, which provides the reader with a guide to sort out current and future biomarkers. Comprehensive and cutting-edge, The Handbook of Biomarkers serves as a vital guide to furthering our understanding of biomarkers, which, by facilitating the combination of therapeutics with diagnostics, promise to play an important role in the development of personalized medicine, one of the most important emerging trends in healthcare today.
The high failure rate in the pharmaceutical industry has positioned biomarkers and personalized medicine in the frontline as possible solutions. If executed right, biomarkers and companion diagnostics (CDx) can potentially help the drug industry enhance the probability of success, accelerating time to market, and, more importantly, benefit patients by supporting accurate diagnosis and selection of the most effective and least toxic therapies. Biomarkers, Diagnostics, and Precision Medicine in the Drug Industry aims to examine the challenges and limitations in biomarkers and laboratory tests. It also offers advice on best practices to ensure proper application of biomarkers and bridges the gap between diagnostic business development claims and real-life deliverables. The book covers biomarkers for different purposes, provides examples from different technologies which includes standard-of-care approved assays as well as for-investigational-use and for-research-use-only assays. It also includes new data for biomarkers in different therapeutic indications and offers case studies and practical examples. Biomarkers, Diagnostics, and Precision Medicine in the Drug Industry serves as a reference to drug developers, IVD providers, healthcare givers, academics, and researchers for best practices to help increase the probability of success.
Provides the unique insight of an expert with extensive experience in diagnostics and clinical laboratory on one side and drug discovery and development on the other side
Addresses the challenges of drug development and precision medicine and suggests how to eliminate or mitigate these challenges through better utilization of biomarkers and diagnostics in drug development and patient management
Features case studies and real-life examples from different classes of biomarkers on different platforms for different therapeutic areas
Автор: Martin Ingelsson; Lars Lannfelt Название: Immunotherapy and Biomarkers in Neurodegenerative Disorders ISBN: 1493935585 ISBN-13(EAN): 9781493935581 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With a focus on Alzheimer`s disease, the firstsections of the book examine immunotherapeutic approaches for theaforementioned disease as well as for Parkinson`s disease and Huntington`s disease,amongst others.
Автор: Martin Ingelsson; Lars Lannfelt Название: Immunotherapy and Biomarkers in Neurodegenerative Disorders ISBN: 1493980785 ISBN-13(EAN): 9781493980789 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With a focus on Alzheimer`s disease, the firstsections of the book examine immunotherapeutic approaches for theaforementioned disease as well as for Parkinson`s disease and Huntington`s disease,amongst others.
Автор: Yihong Yao Название: Genomic Biomarkers for Pharmaceutical Development, ISBN: 0123973368 ISBN-13(EAN): 9780123973368 Издательство: Elsevier Science Рейтинг: Цена: 11193.00 р. Наличие на складе: Поставка под заказ.
Описание: Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing the inherent challenges of targeting the appropriate indications, biomarker robustness, regulatory hurdles, commercialization and much more. It features case studies devoted to the applications of pharmacogenomics, toxicogenomics, and other genetic technologies as they support drug discovery and development. . With chapters written by international authorities in industry and academia, this work is a truly unique presentation of the thoughts and approaches that lead to the development of personalized medicine. Intended for all those involved in clinical translational research, this book is the ideal resource for scientists searching for the applications, strategies and successful approaches of translational science in pharmaceutical development.
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