Non-Coding Rnas in Cardiovascular Diseases, Xiao Junjie

Автор: Xia Li; Juan Xu; Yun Xiao; Shangwei Ning; Yunpeng
Название: Non-coding RNAs in Complex Diseases
ISBN: 9811307180 ISBN-13(EAN): 9789811307188
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This book offers an in-depth and comprehensive review on current understanding of regulatory ncRNAs in complex diseases from a view of bioinformatics. It conveys state-of-the-art bioinformatics tools and methods for ncRNAs from computational detection, functional prediction, to their roles in diseases. Computational methods used to investigate uncharacterised ncRNAs in diseases are mainly summarized in seven aspects: DNA variation of ncRNAs in diseases, prioritization of disease-related ncRNAs, dysregulation epigenetic factors that regulate ncRNA misexpression (DNA methylation and histone-modification), complex crosstalk across ncRNAs, ncRNAs acted as competing regulators to mediate the expression of protein-coding genes, non-coding RNAs mediated risk pathways,and their contributions to drug target predictions. The generally used data resources of ncRNAs are also listed in the end. This book provides important information on the current progress in the fast-moving fields of bioinformatics for regulatory ncRNAs. It provides a timely and useful reference for computational biologists, specifically with RNA interests, and other related areas.Prof. Xia Li is a Professor and the Dean of College of Bioinformatics Science and Technology, Harbin Medical University, China. Dr. Yun Xiao, Dr. Juan Xu, Dr. Shangwei Ning and Dr. Yunpeng Zhang are from College of Bioinformatics Science and Technology, Harbin Medical University, China.

Автор: Xia Li; Juan Xu; Yun Xiao; Shangwei Ning; Yunpeng
Название: Non-coding RNAs in Complex Diseases
ISBN: 9811344868 ISBN-13(EAN): 9789811344862
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This book offers an in-depth and comprehensive review on current understanding of regulatory ncRNAs in complex diseases from a view of bioinformatics. It conveys state-of-the-art bioinformatics tools and methods for ncRNAs from computational detection, functional prediction, to their roles in diseases. Computational methods used to investigate uncharacterised ncRNAs in diseases are mainly summarized in seven aspects: DNA variation of ncRNAs in diseases, prioritization of disease-related ncRNAs, dysregulation epigenetic factors that regulate ncRNA misexpression (DNA methylation and histone-modification), complex crosstalk across ncRNAs, ncRNAs acted as competing regulators to mediate the expression of protein-coding genes, non-coding RNAs mediated risk pathways,and their contributions to drug target predictions. The generally used data resources of ncRNAs are also listed in the end. This book provides important information on the current progress in the fast-moving fields of bioinformatics for regulatory ncRNAs. It provides a timely and useful reference for computational biologists, specifically with RNA interests, and other related areas.Prof. Xia Li is a Professor and the Dean of College of Bioinformatics Science and Technology, Harbin Medical University, China. Dr. Yun Xiao, Dr. Juan Xu, Dr. Shangwei Ning and Dr. Yunpeng Zhang are from College of Bioinformatics Science and Technology, Harbin Medical University, China.

Название: Long non-coding rnas in human disease
ISBN: 3319239066 ISBN-13(EAN): 9783319239064
Издательство: Springer
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Цена: 19591.00 р.
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Описание: The role oflncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, pastretroelements integrated within the human genome, as well as the role thesepseudogene-derived lncRNAs play in cancer development are discussed in detail.

Автор: Catherine M. Greene
Название: MicroRNAs and Other Non-Coding RNAs in Inflammation
ISBN: 3319382306 ISBN-13(EAN): 9783319382302
Издательство: Springer
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Цена: 18284.00 р.
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Описание: The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.e.

Автор: Khalil Ahmad M.
Название: Molecular Biology of Long Non-Coding Rnas
ISBN: 3030170888 ISBN-13(EAN): 9783030170882
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Advances in the field also include better characterization of human long non-coding RNAs, novel insights into their roles in human development and disease, their diverse mechanisms of action and novel technologies to study them.

Автор: Morris Kevin V.
Название: Long Non-Coding Rnas in Human Disease
ISBN: 3319795511 ISBN-13(EAN): 9783319795515
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.

Автор: Slaby Ondrej, Calin George A.
Название: Non-Coding Rnas in Colorectal Cancer
ISBN: 3319824910 ISBN-13(EAN): 9783319824918
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer. This work further provides the comprehensive overview and novel insights into using of non-coding RNAs as colorectal cancer biomarkers enabling early detection of the disease, prognostic stratification of the patients and prediction of therapeutic response. The reader is introduced to the overview of modern non-coding RNAs-based therapeutic strategies, and summary of their preclinical testing performed in colorectal cancer. The work is written for researchers who want to explore current state of the knowledge in this interesting field of molecular oncology.

Автор: Yi Feng; Lin Zhang
Название: Long Non-Coding RNAs
ISBN: 1493933760 ISBN-13(EAN): 9781493933761
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume assembles a broad spectrum of methods used in long non-coding RNAs (lncRNA) research, ranging from computational annotation of lncRNA genes to molecular and cellular analyses of the function of individual lncRNA.

Автор: Ahmad M. Khalil
Название: Molecular Biology of Long Non-coding RNAs
ISBN: 3030170853 ISBN-13(EAN): 9783030170851
Издательство: Springer
Рейтинг:
Цена: 15372.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Advances in the field also include better characterization of human long non-coding RNAs, novel insights into their roles in human development and disease, their diverse mechanisms of action and novel technologies to study them.

Автор: Volker A. Erdmann; Jan Barciszewski
Название: Non Coding RNAs in Plants
ISBN: 3642269990 ISBN-13(EAN): 9783642269998
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Discovered just 20 years ago, ncRNAs have been dubbed the `secret regulators` of cells. Only recently has their function in plants been investigated. In this book leading researchers relate recent discoveries about the role played by small ncRNA in plants.

Автор: Yi Feng; Lin Zhang
Название: Long Non-Coding RNAs
ISBN: 1493980351 ISBN-13(EAN): 9781493980352
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This volume assembles a broad spectrum of methods used in long non-coding RNAs (lncRNA) research, ranging from computational annotation of lncRNA genes to molecular and cellular analyses of the function of individual lncRNA.

Автор: Muller Fabbri
Название: Non-coding RNAs and Cancer
ISBN: 1493952374 ISBN-13(EAN): 9781493952373
Издательство: Springer
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Цена: 19589.00 р.
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Описание: This book provides essential information of the biogenesis, physiology and de-regulation of non-coding RNAs in cancer. It guides the reader to the most widely and effectively used bioinformatic approaches to the study of miRNAs.