Tumor Microenvironment: Recent Advances, Birbrair Alexander
Автор: Andrei Thomas-Tikhonenko Название: Cancer Genome and Tumor Microenvironment ISBN: 1461425247 ISBN-13(EAN): 9781461425243 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: There exists a large body of evidence suggesting that well-known mutations in cancer genes profoundly affect tumor milieu. The reviews in this book explore in detail how tumor microenvironment and progression are "hard-wired" at the genetic level.
Автор: Ursini-Siegel Josie, Beauchemin Nicole Название: The Tumor Microenvironment: Methods and Protocols ISBN: 1493981439 ISBN-13(EAN): 9781493981434 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers core and emerging in vitro and in vivo protocols used to study how various components of the tumor microenvironment are established and subsequently interact with tumor cells to facilitate carcinogenesis.
Автор: Ursini-Siegel Название: The Tumor Microenvironment ISBN: 1493937995 ISBN-13(EAN): 9781493937998 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers core and emerging in vitro and in vivo protocols used to study how various components of the tumor microenvironment are established and subsequently interact with tumor cells to facilitate carcinogenesis. In addition, the book examines research topics including cellular and molecular biology approaches, in vivo genetic approaches, various “omics”-based strategies, therapeutic strategies to target the microenvironment, and, finally, advanced techniques in the fields of tissue engineering and nanotechnology. Written and validated in the laboratories of a number of trusted collaborating authors for the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Practical and authoritative, The Tumor Microenvironment: Methods and Protocols constitutes a compendium of techniques now available to a broad audience, including basic and clinician scientists, systems biologists, and biological engineers.
1 The genomic complexity of osteosarcoma and its implication for preclinical and clinical targeted therapies
2 Genomics and the Immune Landscape of Osteosarcoma
3 RECQ DNA Helicases and Osteosarcoma
4 Targeting the Cancer Epigenome with Histone Deacetylase Inhibitors in Osteosarcoma
5 Oncolytic viruses and their potential as a therapeutic opportunity in Osteosarcoma
6 Applying Osteosarcoma Immunology to Understand Disease Progression and Assess immunotherapeutic Response
7 Targetable intercellular signaling pathways facilitate lung colonization in osteosarcoma
8 Wnt Signaling in Osteosarcoma
9 Receptor Tyrosine Kinases in Osteosarcoma: 2019 update
10 The Role of ALDH in the Metastatic Potential of Osteosarcoma Cells and Potential ALDH Targets
11 Autophagy in OS
12 Fas signaling as a potential target for the treatment of osteosarcoma metastasis in the lungs
13 Exosomes: Dynamic Mediators of Extracellular Communication in the Tumor Microenvironment
14 Comparative Immunology and Immunotherapy of Canine Osteosarcoma
Index
Автор: Rebecca G. Bagley Название: The Tumor Microenvironment ISBN: 146142660X ISBN-13(EAN): 9781461426608 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explores the many biological and physical aspects of the tumor microenvironment. It represents a superb compilation of the latest thoughts and data on this topic, and the in-depth chapters are written by known professionals in the field.
Описание: This work describes the importance of tumor microenvironment in favouring tumor progression and angiogenesis. Under physiological conditions, angiogenesis is dependent on the balance of positive and negative angiogenic modulators within the vascular microenvironment and requires the functional activities of a number of molecules, including angiogenic factors, extracellular matrix proteins, adhesion molecules and proteolytic enzymes. In normal tissues, vascular quiescence is maintained by the dominant influence of endogenous angiogenesis inhibitors over angiogenic stimuli. Tumor angiogenesis is linked to a switch in the balance between positive and negative regulators, and mainly depends on the release by inflammatory or neoplastic cells of specific growth factors for endothelial cells, that stimulate the growth of the blood vessels of the host or the down-regulation of natural angiogenesis inhibitors. In particular, the inflammatory infiltrate may contribute to tumor angiogenesis, and there are many reports of associations between tumor inflammatory infiltrate, vascularity and prognosis. New therapeutic approaches have been developed with the aim to control tumor angiogenesis through targeting of different components of tumor microenvironment.
Автор: Koumenis Название: Tumor Microenvironment ISBN: 3319266640 ISBN-13(EAN): 9783319266640 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume covers the topics presented at the 3rd International Conference on Tumor Microenvironment and Cellular Stress by an international community of researchers. The conference brings together scientists to discuss different cellular and animal models of tumor microenvironment study and identify common pathways that are candidates for therapeutic intervention; stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology (e.g., HIF regulation) and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery; and critically evaluate novel targets for imaging or therapeutic intervention that would be of use to the tumor microenvironment community and pharmaceutical industry.
Автор: Aref Amir R., Barbie David Название: Ex Vivo Engineering of the Tumor Microenvironment ISBN: 3319832824 ISBN-13(EAN): 9783319832821 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo.
Автор: Birbrair Alexander Название: Tumor Microenvironment: Hematopoietic Cells - Part a ISBN: 3030357228 ISBN-13(EAN): 9783030357221 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment.
Автор: Rejniak Название: Systems Biology of Tumor Microenvironment ISBN: 3319420216 ISBN-13(EAN): 9783319420219 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This edited volume discusses the complexity of tumor microenvironments during cancer development, progression and treatment. Each chapter presents a different mathematical model designed to investigate the interactions between tumor cells and the surrounding stroma and stromal cells. The topics covered in this book include the quantitative image analysis of a tumor microenvironment, the microenvironmental barriers in oxygen and drug delivery to tumors, the development of tumor microenvironmental niches and sanctuaries, intravenous transport of the circulating tumor cells, the role of the tumor microenvironment in chemotherapeutic interventions, the interactions between tumor cells, the extracellular matrix, the interstitial fluid, and the immune and stromal cells. Mathematical models discussed here embrace both continuous and agent-based approaches, as well as mathematical frameworks of solid mechanics, fluid dynamics and optimal control theory. The topics in each chapter will be of interest to a biological community wishing to apply the mathematical methods to interpret their experimental data, and to a biomathematical audience interested in exploring how mathematical models can be used to address complex questions in cancer biology.
Описание: Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on the extracellular matrix components of the tumor microenvironment during cancer development.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
