Translational Neuroscience: Fundamental Approaches for Neurological Disorders, Tuszynski Mark H.
Автор: Haines Duane E. Название: Fundamental Neuroscience for Basic and Clinical Applications ISBN: 0323396321 ISBN-13(EAN): 9780323396325 Издательство: Elsevier Science Рейтинг: Цена: 12968.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Using a rigorous yet clinically-focused approach, Fundamental Neuroscience for Basic and Clinical Applications, 5th Edition, covers the fundamental neuroscience information needed for coursework, exams, and beyond. It integrates neuroanatomy, pharmacology, and physiology, and offers a full section devoted to systems neurobiology, helping you comprehend and retain the complex material you need to know.
Highlights clinical content in blue
throughout the text, helping you focus on what you need to know in the clinical environment.
Presents thoroughly updated information in every chapter, with an emphasis on new clinical thinking as related to the brain and systems neurobiology.
Features hundreds of correlated state-of-the-art imaging examples, anatomical diagrams, and histology photos - nearly half are new or improved for this edition.
Pays special attention to the correct use of clinical and anatomical terminology, and provides new clinical text and clinical-anatomical correlations.
Автор: Tanu Wadhera, Deepti Kakkar Название: Interdisciplinary Approaches to Altering Neurodevelopmental Disorders ISBN: 1799830691 ISBN-13(EAN): 9781799830696 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 39640.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Explores neurodevelopmental disorders and a diverse array of diagnostic tools and therapies assisted by neurotechnological devices. The book covers a wide range of topics, including individual-centred design, artificial intelligence, and multifaceted therapies.
Название: Translational neuroscience ISBN: 1489976523 ISBN-13(EAN): 9781489976529 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Chapter 1 - Introduction - Mark H. Tuszynski
Section 1: Molecular Approaches
Chapter 2 - Gene Therapy of CNS Disorders using Recombinant AAV vectors - Giridhar Murlidharan, R. Jude Samulski and Aravind Asokan
Chapter 3 - NGF and BDNF Gene Therapy for Alzheimer's Disease - Alan H. Nagahara and Mark H. Tuszynski
Chapter 4 - GDNF and AADC Gene Therapy for Parkinson's Disease - Krystof Bankiewicz, Waldy San Sebastian, Lluis Samaranch and John Forsayeth
Chapter 5 - GAD Gene Therapy for Parkinson's Disease - Michael G. Kaplitt and Matthew J. During
Chapter 6 - Anti-sense Oligonucleotides
for Amyotrophic Lateral Sclerosis - Wade K. Self and Timothy M. Miller
Chapter 7 - Gene therapy for Inborn Errors of Metabolism: Batten Disease - Dolan Sondhi, Ronald G. Crystal and Stephen M. Kaminsky
Chapter 8 - Gene Therapy for Spinal Cord Injury - Ioana Goganau and Armin Blesch
Chapter 9 - Gene Therapy for Epilepsy - Thomas J. McCown
Chapter 10 - Gene therapy for Pain - Darren Wolfe, David Krisky, James Goss, James Wechuck, Marina Mata and David J. Fink
Section 2: Cellular Approaches
Chapter 11 - Stem Cells for Parkinson's Disease - Andrйs Bratt-Lealand Jeanne F. Loring
quot;serif"">Chapter 12 - Could Stem Cells be used to treat or model Alzheimer's Disease? - Edsel M. Abud and Mathew Blurton-Jones
Chapter 13 - Stem cells for Amyotrophic Late
ral Sclerosis - Anthony Donsante, Lindsey Nicole Urquia and Nicholas M. Boulis
Chapter 14 - Stem cells for Multiple Sclerosis - Pamela Sarkar and Neil Scolding
Chapter 15 - Cell Therapy for Pediatric Disorders of Glia - Joana M. Osorio and Steven A. Goldman
Chapter 16 - Neural Stem Cells for Spinal Cord Injury - Paul Lu, Ruhel Amhad
le="mso-bidi-font-size:12.0pt;font-family: "Times New Roman","serif""> and Mark H. Tuszynski
Chapter 17 - Marrow-derived Mesenchymal Stromal Cells in the Treatment of Stroke - Steve C. Cramer
Chapter 19 - Discovery of Potent Gamma Secretase Modulators for the Treatment of Alzheimer's Disease - Kevin D. Rynearson, Rudolph E. Tanzi and Steven L. Wagner
Chapter 20 - Blocking the Nogo-A signalling pathway to promote regeneration and pla
sticity after spinal cord injury and stroke - tachment: initial; background-size: initial; background-origin: initial; background-clip: initial; background-position: initial; background-repeat: initial;">Anna Magdalena Guzik-Kornacka, Flуra Vajda, Martin E. Schwab
Chapter 21 - Intrinsic neuronal mechanisms in axon regeneration after spinal cord injury - Fengfeng Bei and Zhigang He
Chapter 22 - Voltage-gated ion channels as molecula
r targets for pain - Gerald W. Zamponi, Chongyang Hanand Stephen G. Waxman
Section 4: Activity-Dependent Plasticity and Neurorehabilitation
Chapter 24 - Neural Prostheses for Neurotrauma - Arthur Prochazka
Chapter 25 - Why is Fu
nctional Electrical Stimulation Therapy Capable of Restoring Motor Function Following Severe Injury to the Central Nervous System? - Mary K. Nagai, Cesar Marquez-Chin and Milos R. Popovic
Chapter 26 - Deep Brain Stimulation for Neuropsychiatric Disorders - Ausaf A. Bari, Nicolas Kon Kam King, Nir Lipsman and Andres M. Lozano
Chapter 27 - Novel Interventions for Stroke: Nervous System Cooling - Patrick D. Lyden, Jessica Lamb and Padmesh S. Rajput
Описание: Examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This title focuses on the neurosciences, neurology, and literature that shows how science and the humanities can come together - and have come together in the past.
Название: Biomarkers of Brain Injury and Neurological Disorders ISBN: 1482239825 ISBN-13(EAN): 9781482239829 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book explores the recent advances in the techniques and platforms used in biomarker research that have revolutionized the way we study, diagnose, and treat brain injury conditions. The contributors describe different biomarker studies pertaining to brain injury and other neurological disorders and analyze the different models and technologies used to identify these biological markers. The book includes findings from "Omics research" that have been utilized to decipher and identify such biomarkers. It discusses protein, microRNA, and altered gene profiles and reviews neurological disorders such as multiple sclerosis, Charcot-Marie-Tooth disease, and prion and Alzheimer's disease.
Описание: This volume highlights proteomics studies of quantitative PTM changes in both peripheral and central nervous system proteomes utilizing the most recent advances in mass spectrometry. Chapters include practical information pertaining to the fundamentals of sample preparation, liquid chromatography, and tandem mass spectrometry instrumental analysis and will elucidate best practices in the interpretation of data using modern bioinformatics approaches. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.Authoritative and practical, Analysis of Post-Translational Modifications and Proteolysis in Neuroscience aims to ensure successful results in the further study of this vital field.
Автор: Larry Squire Название: Fundamental Neuroscience, ISBN: 0123858704 ISBN-13(EAN): 9780123858702 Издательство: Elsevier Science Рейтинг: Цена: 14315.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Offers a comprehensive presentation of the discipline of neuroscience, from molecules to cognition. This book builds from an introductory section that includes fundamental neuroanatomy and covers cellular and molecular neuroscience, development, sensory systems, motor systems, regulatory systems, and behavioral and cognitive neuroscience.
Описание: This case series book offers a practical and accessible approach to psychiatry, addressing major clinical problems ranging from psychosis to aging effects, each of which is tackled as it arises in everyday settings.
Описание: A comprehensive book that reviews advances in ocular motor research on topics of general interest, rare, specialized or unique conditions, and pertinent basic neuroscience. A rare collection with contributions from basic neuroscientists, neurologists, and ophthalmologists. Includes dedicated chapters on mathematical models, pharmacotherapy, neuromodulation, motion perception, visual influence on eye movement, physiology of strabismus, and microsaccades. This book is dedicated to David Robinson - one of the pioneers of contemporary ocular motor and vestibular neuroscience.
Автор: Conn, P. Michael Название: Conn`s Translational Neuroscience ISBN: 0128023813 ISBN-13(EAN): 9780128023815 Издательство: Elsevier Science Рейтинг: Цена: 20212.00 р. Наличие на складе: Поставка под заказ.
Описание:
Conn's Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain, ' with the results providing insight into the underlying basis of many neurological disease processes.
This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis.
In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn's Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance.
A critical examination of translational medicine, when private risk is transferred to the public sector and university research teams become tech startups for global investors.
A global shift has secretly transformed science and medicine. Starting in 2003, biomedical research in the West has been reshaped by the emergence of translational science and medicine--the idea that the aim of research is to translate findings as quickly as possible into medical products. In The Market in Mind, Mark Dennis Robinson charts this shift, arguing that the new research paradigm has turned university research teams into small biotechnology startups and their industry partners into early-stage investment firms. There is also a larger, surprising consequence from this shift: according to Robinson, translational science and medicine enable biopharmaceutical firms, as part of a broader financial strategy, to outsource the riskiest parts of research to nonprofit universities. Robinson examines the implications of this new configuration. What happens, for example, when universities absorb unknown levels of risk? Robinson argues that in the years since the global financial crisis translational science and medicine has brought about "the financialization of health."
Robinson explores such topics as shareholder anxiety and industry retreat from Alzheimer's and depression research; how laboratory research is understood as health innovation even when there is no product; the emergence of investor networking events as crucial for viewing science in a market context; and the place of patients in research decisions. Although translational medicine justifies itself by the goal of relieving patients' suffering, Robinson finds patients' voices largely marginalized in translational neuroscience.
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