Bioinformatics in Microrna Research, Huang Jingshan, Borchert Glen M., Dou Dejing
Автор: Kavi Kishor P.B.; Rajib Bandopadhyay; Prashanth Su Название: Agricultural Bioinformatics ISBN: 8132234863 ISBN-13(EAN): 9788132234869 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A common approach to understanding the functional repertoire of a genome is through functional genomics. With systems biology burgeoning, bioinformatics has grown to a larger extent for plant genomes where several applications in the form of protein-protein interactions (PPI) are used to predict the function of proteins. With plant genes evolutionarily conserved, the science of bioinformatics in agriculture has caught interest with myriad of applications taken from bench side to in silico studies. A multitude of technologies in the form of gene analysis, biochemical pathways and molecular techniques have been exploited to an extent that they consume less time and have been cost-effective to use. As genomes are being sequenced, there is an increased amount of expression data being generated from time to time matching the need to link the expression profiles and phenotypic variation to the underlying genomic variation. This would allow us to identify candidate genes and understand the molecular basis/phenotypic variation of traits. While many bioinformatics methods like expression and whole genome sequence data of organisms in biological databases have been used in plants, we felt a common reference showcasing the reviews for such analysis is wanting. We envisage that this dearth would be facilitated in the form of this Springer book on Agricultural Bioinformatics. We thank all the authors and the publishers Springer, Germany for providing us an opportunity to review the bioinformatics works that the authors have carried in the recent past and hope the readers would find this book attention grabbing.
Автор: Lesk Название: Introduction to Bioinformatics ISBN: 0199277877 ISBN-13(EAN): 9780199277872 Издательство: Oxford Academ Цена: 3958.00 р. Наличие на складе: Поставка под заказ.
Описание: Introduces the student to the power of bioinformatics as a set of scientific tools. This book explains how to access the data archives of genomes and proteins, and the kind of questions these data and tools can answer - how to make inferences from the data archives, to make connections among them, and to derive useful and interesting predictions.
Автор: Hans-Joachim B?ckenhauer; Dirk Bongartz Название: Algorithmic Aspects of Bioinformatics ISBN: 3642091008 ISBN-13(EAN): 9783642091001 Издательство: Springer Рейтинг: Цена: 11099.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book introduces some key problems in bioinformatics, discusses the models used to formally describe these problems, and analyzes the algorithmic approaches used to solve them. This book presents formal models in a mathematically precise, yet intuitive manner.
Автор: Jingshan Huang; Glen M. Borchert; Dejing Dou; Jun Название: Bioinformatics in MicroRNA Research ISBN: 1493970445 ISBN-13(EAN): 9781493970445 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. MicroRNAs, Long Non-Coding RNAs, and Their Functions in Human Disease
Min Xue, Ying Zhuo, and Bin Shan
2. MicroRNA Expression: Protein Participants in MicroRNA Regulation
4. MicroRNAs: Biomarkers, Diagnostics, and Therapeutics
Weili Huang
5. Relational Databases and Biomedical Big Data
N.H. Nisansa D. de Silva
6. Semantic Technologies and Bio-Ontologies
Fernando Gutierrez
7. Genome-Wide Analysis of MicroRNA-Regulated Transcripts
David Chevalier and Glen M. Borchert
8. Computational Prediction of MicroRNA Target Genes, Target Prediction Databases, and Web Resources
Justin T. Roberts and Glen M. Borchert
9. Exploring MicroRNA:: Target Regulatory Interactions by Computing Technologies
Yue Hu, Wenjun Lan, and Daniel Miller
10. The Limitations of Existing Approaches in Improving MicroRNA Target Prediction Accuracy
Rasiah Loganantharaj and Thomas A. Randall
11. Genomic Regulation of MicroRNA Expression in Disease Development
Feng Liu
12. Next Generation Sequencing for MicroRNA Expression Profile
Yue Hu, Wenjun Lan, and Daniel Miller
13. Handling High-Dimension (High-Feature) MicroRNA Data
Yue Hu, Wenjun Lan, and Daniel Miller
14. Effective Removal of Noisy Data Via Batch Effect Processing
Ryan G. Benton
15. Logical Reasoning (Inferencing) on MicroRNA Data
Jingsong Wang
16. Machine Learning Techniques in Exploring MicroRNA Gene Discovery, Targets, and Functions
Sumi Singh, Ryan G. Benton, Anurag Singh, and Anshuman Singh
17. Involvement of MicroRNAs in Diabetes and Its Complications
Bin Wu and Daniel Miller
18. MicroRNA Regulatory Networks as Biomarkers in Obesity: The Emerging Role
Lihua Zhang, Daniel Miller, Qiuping Yang, and Bin Wu
19. Expression of MicroRNAs in Thyroid Carcinoma
Gaohong Zhu, Lijun Xie, and Daniel Miller
Автор: Paul Название: Microrna perspectives in health an ISBN: 1138054836 ISBN-13(EAN): 9781138054837 Издательство: Taylor&Francis Рейтинг: Цена: 17609.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explores the role of miRNA as therapeutic agents, the progress made in this direction and the problems that need to be addressed for miRNA based therapies to become successful. It also discusses the basic biology of miRNA sythesis, regulation, and their role in disease biology.
Автор: Malik Yousef; Jens Allmer Название: miRNomics: MicroRNA Biology and Computational Analysis ISBN: 1627037470 ISBN-13(EAN): 9781627037471 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In miRNomics: MicroRNA Biology and Computational Analysis, expert researchers in the field present an overview of the current state of the art and aim to put the respective areas of research into a larger perspective.
Автор: Ulf Schmitz; Olaf Wolkenhauer; Julio Vera Название: MicroRNA Cancer Regulation ISBN: 9402400796 ISBN-13(EAN): 9789402400793 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses the role of microRNAs in the formation and progression of solid tumors. The main focus is on computational methods and applications, together with experimental techniques used to approach all aspects of microRNA regulation in cancer.
Автор: Karl L. Mettinger; Pranela Rameshwar; Vinod Kumar Название: Exosomes, Stem Cells and MicroRNA ISBN: 3030089991 ISBN-13(EAN): 9783030089993 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well as improved health span and life span. The use of exosomes from body fluids to define specific biomarkers for various tumors may also clear the path to patient-targeted treatments by developing exosome-derived microRNA based cancer therapeutics. It is essential reading for graduate students, research fellow and biomedical researchers in academia or the pharmaceutical or biotech industries.
Автор: Rani Название: MicroRNA Profiling ISBN: 1493965220 ISBN-13(EAN): 9781493965229 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume includes comprehensive descriptions of miRNA biogenesis and their role in the development and progression of various human diseases. The first few chapters of MicroRNA Profiling: Methods and Protocols discuss the effects of over-expressing and repressing of a target miRNA and their effects on cell viability and proliferation. The next few chapters explore the protocols for total RNA isolation from cells and cell-derived product including formalin fixed paraffin embedded tissue and plant tissue. The last few chapters discuss isolation and characterization of exosomes from medium conditioned by cell lines, serum, and plasma specimens. This book also includes discussions of several software tools, such as miRandola, PicTar, DIANA, and miRWalk. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and cutting-edge, MicroRNA Profiling: Methods and Protocols is a valuable resource for anyone interested in the field of Micro RNAs.
Автор: Ion Mandoiu; Giri Narasimhan; Yanqing Zhang Название: Bioinformatics Research and Applications ISBN: 3642015506 ISBN-13(EAN): 9783642015502 Издательство: Springer Рейтинг: Цена: 10480.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Constitutes the refereed proceedings of the 5th International Symposium on Bioinformatics Research and Applications, ISBRA 2009, held in Fort Lauderdale, FL, USA, in May 2009. This title covers a wide range of topics, including clustering and classification, gene expression analysis, gene networks, genome analysis, and protein domain interactions.
Описание: This book constitutes the proceedings of the 16th International Symposium on Bioinformatics Research and Applications, ISBRA 2020, held in Moscow, Russia, in December 2020. The 23 full papers and 18 short papers presented in this book were carefully reviewed and selected from 131 submissions.
Автор: Rune Matthiesen Название: Bioinformatics Methods in Clinical Research ISBN: 1617796700 ISBN-13(EAN): 9781617796708 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Covering the latest developments in clinical omics, this volume details the algorithms currently used in publicly available software tools. It looks at statistics, algorithms, automated data retrieval, and experimental consideration in the various omics areas.
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