Aging and Hearing: Causes and Consequences, Helfer Karen S., Bartlett Edward L., Popper Arthur N.
Автор: Semyon M. Slobounov Название: Injuries in Athletics: Causes and Consequences ISBN: 1489993886 ISBN-13(EAN): 9781489993885 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Over the past decade, the scientific information on psychology of injury has increased considerably. The purpose of this book is to accumulate the latest development in psychological analyses, evaluation, and management of sport-related injuries, including traumatic brain injuries.
Автор: Schweizer Название: The Behavioral Consequences of Stroke ISBN: 1461476712 ISBN-13(EAN): 9781461476719 Издательство: Springer Рейтинг: Цена: 24456.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Comprehensive and providing an in-depth review of the behavioral consequences of stroke, this title sheds new light on aspects of critical care stroke treatment, imaging and diagnosis, in-patient treatment, and full range of post-care issues.
Автор: Michael R. D`Andrea Название: Intracellular Consequences of Amyloid in Alzheimer`s Disease ISBN: 0128042567 ISBN-13(EAN): 9780128042564 Издательство: Elsevier Science Рейтинг: Цена: 8083.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: . Consequences of Intracellular Amyloid in Alzheimer’s Disease addresses one of the more currently unresolved aspects confounding Alzheimer’s research, the significance of intraneuronal amyloid. It seeks to explain some of the unresolved questions concerning intracellular amyloid and its origin, entry, and toxicity. . Following up on Dr. D’Andrea’s first book, Bursting Neurons and Fading Memories: An Alternative Hypothesis for the Pathogenesis of Alzheimer’s Disease, this book further examines the Inside-Out or Bursting alternative hypothesis of how amyloid escapes the circulatory system to ultimately enter neurons, also examining whether there is a relationship between intracellular amyloid, amyloid plaques, and cognitive impairment. Through a comprehensive explanation of the currently relevant scientific research on intracellular amyloid compiled in this handy reference, readers will better understand the mechanisms that lead to neuron death.
Автор: Tom A. Schweizer; R. Loch Macdonald Название: The Behavioral Consequences of Stroke ISBN: 1489986200 ISBN-13(EAN): 9781489986207 Издательство: Springer Рейтинг: Цена: 17468.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A comprehensive, state-of-the-art contribution to a field that is rapidly developing, The Behavioral Consequences of Stroke provides a broad overview of the cognitive and neurobehavioral effects of stroke. As attention to paralysis and the more obvious physical disabilities stroke patients incur expands, greater attention is being paid today to the cognitive and neurobehavioral complications that impact stroke morbidity and even functional neurological recovery in patients. Written by an international panel of experts and edited by a neurosurgeon and by a cognitive neuroscientist, this unique title addresses the full range of issues relevant to the field, including epidemiology, general treatment, sensorimotor control after stroke, post-stroke aphasia, memory loss after stroke, post-stroke depression, the role of imaging after a stroke, and an update on some stroke clinical trials, to name just some of the areas covered. Illuminative and an influential addition to the literature, The Behavioral Consequences of Stroke will serve as an invaluable resource for neurologsits, neurosurgeons, physiatrists and other physicians, as well as physical, speech and occupational therapists, nurses, psychologists, and other professionals.
Автор: Silva Sophie Название: Hearing Impairment and Disability ISBN: 1632418207 ISBN-13(EAN): 9781632418203 Издательство: Неизвестно Рейтинг: Цена: 24140.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Cummins Hannah Название: Audiology: Clinical Aspects of Hearing ISBN: 163241726X ISBN-13(EAN): 9781632417268 Издательство: Неизвестно Рейтинг: Цена: 25749.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book the best surgical solutions for conductive hearing loss due to ossicular fixations are thoroughly described and discussed. The first section covers thympanosclerosis, collating all knowledge on the pathogenesis and pathology of this obscure condition, as well as the surgical methods used in fixation of the ossicular chain, when caused by myringosclerosis and tympanosclerosis.The second section covers postinflammatory, posttraumatic, and postoperative bony fixations of the ossicular chain. In the third section, the voluminous topic of otosclerosis, in particular the evolution of stapes surgery, the various stapedectomy and stapedotomy methods, and the complications of surgery for otosclerosis, are covered in great detail. This section also includes the problems that are encountered in otosclerosis surgery when the ear has been affected with chronic otitis.In the fourth section, congenital ossicular fixations and defects are covered along with some new aspects on the classification and embryology of these problems.For all topics, there is in-depth discussion of the pathogenesis and pathology of the diseases in question. Excellent hand-drawn illustrations provide a level of detail and comprehension not attainable through photography.This book will cover tympanosclerotic, bony, and fibrous fixations, retractions, atelectasis, secretory and adhesive otitis, ventilation problems of the middle ear, cholesteatoma in the tympanic cavity and more!
Автор: Lindsay Aitkin Название: Neuronal Mechanisms of Hearing ISBN: 1468439103 ISBN-13(EAN): 9781468439106 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In contrast to the level of interest which is paid to the orga- nization of meetings about the structure and function of the audi- tory periphery, the central auditory system has received little attention in the last several years.
Автор: Le Prell Colleen G., Lobarinas Edward, Popper Arthur N. Название: Translational Research in Audiology, Neurotology, and the Hearing Sciences ISBN: 3319821997 ISBN-13(EAN): 9783319821993 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Translational Research is the interface between basic science and human clinical application, including the entire process from animal studies to human clinical trials (phases I, II, and III). Translational Research moves promising basic science results from the laboratory to bedside application. Yet, this transition is often the least-defined, least-understood part of the research process. Most scientific training programs provide little or no systematic introduction to the issues, challenges, and obstacles that prevent effective research translation, even though these are the key steps that enable high-impact basic science to ultimately result in significant clinical advances that improve patient outcome. This volume will provide an overview of key issues in translation of research from “bedside to bench to bedside”, not only from the perspective of the key funding agencies, but also from the scientists and clinicians who are currently involved in the translational research process. It will attempt to offer insight into real-world experience with intellectual property and technology transfer activities that can help move auditory technologies ahead, as scientists and clinicians typically have little or no formal training in these areas. Translational Research in Audiology and the Hearing Sciences will be aimed at graduate students and postdoctoral investigators, as well as professionals and academics. It is intended to function as a high-profile and up-to-date reference work on Translational Research in the auditory sciences, emphasizing research programs in the traditional areas including drugs and devices, as well as less traditional, still emerging, areas such as sensorineural hearing loss, auditory processing disorder, cochlear implants and hearing aids, and tinnitus therapies.
Автор: Andrew H. Bass; Joseph A. Sisneros; Arthur N. Popp Название: Hearing and Hormones ISBN: 3319799762 ISBN-13(EAN): 9783319799766 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews the growing literature that is consistent with the hypothesis that hormones can regulate auditory physiology and perception across a broad range of animal taxa, including humans. Understanding how hormones modulate auditory function has far reaching implications for advancing our knowledge in the basic biomedical sciences and in understanding the evolution of acoustic communication systems. A fundamental goal of neuroscience is to understand how hormones modulate neural circuits and behavior. For example, steroids such as estrogens and androgens are well-known regulators of vocal motor behaviors used during social acoustic communication. Recent studies have shown that these same hormones can also greatly influence the reception of social acoustic signals, leading to the more efficient exchange of acoustic information.
Автор: Ramkumar Название: Inflammatory Mechanisms in Mediating Hearing Loss ISBN: 3319925067 ISBN-13(EAN): 9783319925066 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Common forms of preventable hearing loss are drug and noise-induced hearing loss which are believed to be produced by a similar mechanism. The generation of reactive oxygen species appears to be a common mechanism mediating hearing loss produced by these different sources. As such, a number of laboratories have focused their research towards identifying the sources of ROS production in the cochlea following administration of chemotherapeutic agents or noise exposure. This led to the identification of ROS generating enzymes, such as xanthine oxidases, nitric oxide synthase, and NADPH oxidases which are activated and/or induced during the development of hearing loss. A consequence of these findings was the implementation of antioxidants in preclinical studies for the treatment of hearing loss. These antioxidants have provided different levels of protection in animal and human studies, but none of these have been approved by the US Food and Drug Administration for the treatment of hearing loss. More recently, it was shown that noise-induced hearing loss was associated with recruitment of inflammatory cells and mediators in the cochlea. This finding would suggest that noise could produce injury to the cochlea which stimulates local and/or circulating inflammatory cells. A similar finding was observed in the cochlea following administration of the anticancer drug, cisplatin. In addition, our laboratory and others have provided a plausible mechanism by which noise or chemotherapeutic agents could stimulate the inflammatory response. Surprisingly, this mechanism involves ROS activation of transcription factors linked to inflammatory processes in the cochlea. These studies have led to the use of anti-inflammatory agents for the treatment of hearing loss. Preliminary studies targeting inflammatory cytokines appear especially promising in preclinical studies. A primary goal of this project is to describe our current understanding of the oxidant hypothesis of noise and drug-induced hearing loss and show how this relates to cochlear inflammation. Several different aspects of the cochlear inflammatory process will be discussed in detail, ranging from the sources of inflammatory cells, chemokines, inflammatory cytokines, and cochlea resident immune cells. Molecular pathways leading to activation of the local inflammatory process will be highlighted and treatment options will be discussed. The relevance of certain clinically used anti-inflammatory interventions, such as trans-typmanic steroids will also be discussed. Furthermore, we will examine recent patents focusing on the use of anti-inflammatory agents for the treatment of drug and noise-induced hearing loss.
Автор: Lindsay Aitkin Название: Hearing — the Brain and Auditory Communication in Marsupials ISBN: 3642637051 ISBN-13(EAN): 9783642637056 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This monograph evolved from years of research into the auditory pathway and hearing of many species of marsupials.
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