Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research, Ahn Chul, Heo Moonseoung, Zhang Song
Название: Analysis of longitudinal data ISBN: 0199676755 ISBN-13(EAN): 9780199676750 Издательство: Oxford Academ Рейтинг: Цена: 8395.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This second edition has been completely revised and expanded to become the most up-to-date and thorough professional reference text in this fast-moving area of biostatistics. It contains an additional two chapters on fully parametric models for discrete repeated measures data and statistical models for time-dependent predictors.
Автор: Newsom Название: Longitudinal Data Analysis ISBN: 0415874149 ISBN-13(EAN): 9780415874144 Издательство: Taylor&Francis Рейтинг: Цена: 22202.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book provides accessible treatment to state-of-the-art approaches to analyzing longitudinal studies. Comprehensive coverage of the most popular analysis tools allows readers to pick and choose the techniques that best fit their research. The analyses are illustrated with examples from major longitudinal data sets including practical information about their content and design. Illustrations from popular software packages offer tips on how to interpret the results. Each chapter features suggested readings for additional study and a list of articles that further illustrate how to implement the analysis and report the results. Syntax examples for several software packages for each of the chapter examples are provided at www.psypress.com/longitudinal-data-analysis.
Although many of the examples address health or social science questions related to aging, readers from other disciplines will find the analyses relevant to their work. In addition to demonstrating statistical analysis of longitudinal data, the book shows how to interpret and analyze the results within the context of the research design. The methods covered in this book are applicable to a range of applied problems including short- to long-term longitudinal studies using a range of sample sizes.
The book provides non-technical, practical introductions to the concepts and issues relevant to longitudinal analysis. Topics include use of publicly available data sets, weighting and adjusting for complex sampling designs with longitudinal studies, missing data and attrition, measurement issues related to longitudinal research, the use of ANOVA and regression for average change over time, mediation analysis, growth curve models, basic and advanced structural equation models, and survival analysis.
An ideal supplement for graduate level courses on data analysis and/or longitudinal modeling taught in psychology, gerontology, public health, human development, family studies, medicine, sociology, social work, and other behavioral, social, and health sciences, this multidisciplinary book will also appeal to researchers in these fields.
Accurate sample size calculation ensures that clinical studies have adequate power to detect clinically meaningful effects. This results in the efficient use of resources and avoids exposing a disproportionate number of patients to experimental treatments caused by an overpowered study.
Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies.
The book focuses on issues specific to the two types of correlated outcomes: longitudinal and clustered. For clustered studies, the authors provide sample size formulas that accommodate variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas to account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the level at which to perform randomization actually becomes a design parameter. The authors show how this can greatly impact trial administration, analysis, and sample size requirement.
Addressing the overarching theme of sample size determination for correlated outcomes, this book provides a useful resource for biostatisticians, clinical investigators, epidemiologists, and social scientists whose research involves trials with correlated outcomes. Each chapter is self-contained so readers can explore topics relevant to their research projects without having to refer to other chapters.
Автор: Brajendra C. Sutradhar Название: Dynamic Mixed Models for Familial Longitudinal Data ISBN: 1461428017 ISBN-13(EAN): 9781461428015 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a theoretical foundation for analysis of discrete data such as count and binary data in the longitudinal setup. It presents differences between the familial and longitudinal correlation models, and illustrations of real life data analysis.
Автор: Elashoff Название: Joint Modeling of Longitudinal and Time-to-Event Data ISBN: 1439807825 ISBN-13(EAN): 9781439807828 Издательство: Taylor&Francis Рейтинг: Цена: 14086.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Longitudinal studies often incur several problems that challenge standard statistical methods for data analysis. These problems include non-ignorable missing data in longitudinal measurements of one or more response variables, informative observation times of longitudinal data, and survival analysis with intermittently measured time-dependent covariates that are subject to measurement error and/or substantial biological variation. Joint modeling of longitudinal and time-to-event data has emerged as a novel approach to handle these issues.
Joint Modeling of Longitudinal and Time-to-Event Data provides a systematic introduction and review of state-of-the-art statistical methodology in this active research field. The methods are illustrated by real data examples from a wide range of clinical research topics. A collection of data sets and software for practical implementation of the joint modeling methodologies are available through the book website.
This book serves as a reference book for scientific investigators who need to analyze longitudinal and/or survival data, as well as researchers developing methodology in this field. It may also be used as a textbook for a graduate level course in biostatistics or statistics.
Автор: Rizopoulos Dimitris Название: Joint Models of Longitudinal and Time-to-Event Data ISBN: 1439872864 ISBN-13(EAN): 9781439872864 Издательство: Taylor&Francis Рейтинг: Цена: 13779.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
In follow-up studies it is often of interest to investigate how a longitudinal outcome that is repeatedly measured in time is associated with a time to an event of interest. Typical examples in this setting come from biomarker research, such as HIV studies where longitudinal CD4 cell counts and viral load are collected in conjunction to the time-to-death, and prostate cancer studies where longitudinal PSA level measurements are collected in conjunction with the time-to-recurrence.
This book is the first providing a full treatment of random effects joint models for longitudinal and time-to-event outcomes that can be utilized to analyze such data. The content is primarily explanatory focusing on applications of joint modeling, but sufficient mathematical details are provided to facilitate understanding of the key features of these models. All illustrations put forward can be implemented in the R programming language via the freely available package JM written by the author.
Автор: Chow, Shein-chung Shao, Jun Wang, Hansheng Lokhnygina, Yuliya Название: Sample size calculations in clinical research ISBN: 0367657767 ISBN-13(EAN): 9780367657765 Издательство: Taylor&Francis Рейтинг: Цена: 5970.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Like the well-regarded and bestselling second edition, Sample Size Calculations in Clinical Research, Third Edition, presents statistical procedures for performing sample size calculations during various phases of clinical research and development. This new edition contains updates and four new chapters written specifically for this v
Longitudinal Analysis provides an accessible, application-oriented treatment of introductory and advanced linear models for within-person fluctuation and change. Organized by research design and data type, the text uses in-depth examples to provide a complete description of the model-building process. The core longitudinal models and their extensions are presented within a multilevel modeling framework, paying careful attention to the modeling concerns that are unique to longitudinal data. Written in a conversational style, the text provides verbal and visual interpretation of model equations to aid in their translation to empirical research results. Overviews and summaries, boldfaced key terms, and review questions will help readers synthesize the key concepts in each chapter.
Written for non-mathematically-oriented readers, this text features:
A description of the data manipulation steps required prior to model estimation so readers can more easily apply the steps to their own data
An emphasis on how the terminology, interpretation, and estimationof familiar general linear models relates to those of more complex models for longitudinal data
Integrated model comparisons, effect sizes, and statistical inference in each example to strengthen readers' understanding of the overall model-building process
Sample results sections for each example to provide useful templates for published reports
Examples using both real and simulated data in the text, along with syntax and output for SPSS, SAS, STATA, and Mplus at www.PilesOfVariance.com to help readers apply the models to their own data
The book opens with the building blocks of longitudinal analysis--general ideas, the general linear model for between-person analysis, and between- and within-person models for the variance and the options within repeated measures analysis of variance. Section 2 introduces unconditional longitudinal models including alternative covariance structure models to describe within-person fluctuation over time and random effects models for within-person change. Conditional longitudinal models are presented in section 3, including both time-invariant and time-varying predictors. Section 4 reviews advanced applications, including alternative metrics of time in accelerated longitudinal designs, three-level models for multiple dimensions of within-person time, the analysis of individuals in groups over time, and repeated measures designs not involving time. The book concludes with additional considerations and future directions, including an overview of sample size planning and other model extensions for non-normal outcomes and intensive longitudinal data.
Class-tested at the University of Nebraska-Lincoln and in intensive summer workshops, this is an ideal text for graduate-level courses on longitudinal analysis or general multilevel modeling taught in psychology, human development and family studies, education, business, and other behavioral, social, and health sciences. The book's accessible approach will also help those trying to learn on their own. Only familiarity with general linear models (regression, analysis of variance) is needed for this text.
Longitudinal Analysis provides an accessible, application-oriented treatment of introductory and advanced linear models for within-person fluctuation and change. Organized by research design and data type, the text uses in-depth examples to provide a complete description of the model-building process. The core longitudinal models and their extensions are presented within a multilevel modeling framework, paying careful attention to the modeling concerns that are unique to longitudinal data. Written in a conversational style, the text provides verbal and visual interpretation of model equations to aid in their translation to empirical research results. Overviews and summaries, boldfaced key terms, and review questions will help readers synthesize the key concepts in each chapter.
Written for non-mathematically-oriented readers, this text features:
A description of the data manipulation steps required prior to model estimation so readers can more easily apply the steps to their own data
An emphasis on how the terminology, interpretation, and estimationof familiar general linear models relates to those of more complex models for longitudinal data
Integrated model comparisons, effect sizes, and statistical inference in each example to strengthen readers' understanding of the overall model-building process
Sample results sections for each example to provide useful templates for published reports
Examples using both real and simulated data in the text, along with syntax and output for SPSS, SAS, STATA, and Mplus at www.PilesOfVariance.com to help readers apply the models to their own data
The book opens with the building blocks of longitudinal analysis--general ideas, the general linear model for between-person analysis, and between- and within-person models for the variance and the options within repeated measures analysis of variance. Section 2 introduces unconditional longitudinal models including alternative covariance structure models to describe within-person fluctuation over time and random effects models for within-person change. Conditional longitudinal models are presented in section 3, including both time-invariant and time-varying predictors. Section 4 reviews advanced applications, including alternative metrics of time in accelerated longitudinal designs, three-level models for multiple dimensions of within-person time, the analysis of individuals in groups over time, and repeated measures designs not involving time. The book concludes with additional considerations and future directions, including an overview of sample size planning and other model extensions for non-normal outcomes and intensive longitudinal data.
Class-tested at the University of Nebraska-Lincoln and in intensive summer workshops, this is an ideal text for graduate-level courses on longitudinal analysis or general multilevel modeling taught in psychology, human development and family studies, education, business, and other behavioral, social, and health sciences. The book's accessible approach will also help those trying to learn on their own. Only familiarity with general linear models (regression, analysis of variance) is needed for this text.
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