Sample size calculations in clinical research, Chow, Shein-chung Shao, Jun Wang, Hansheng Lokhnygina, Yuliya
Автор: Brown M.J. et al. Название: Clinical Pharmacology, 12 ed. IE ISBN: 0702073296 ISBN-13(EAN): 9780702073298 Издательство: Elsevier Science Рейтинг: Цена: 5746.00 р. Наличие на складе: Поставка под заказ.
Описание:
'The very last thing a drug regulator wishes to be able to say is, like Lord Byron (1788-1824), on the publication of his poem Childe Harold's Pilgrimage, 'I awoke one morning and found myself famous.'
The twelfth edition of this long-established textbook of clinical pharmacology (first published in 1960) continues its fine tradition of balancing science and practice for improved evidence-based drug therapy and good prescribing in therapeutic settings increasingly complicated by intercurrent disease and polypharmacy.
Автор: Bradley Efron and Trevor Hastie Название: Computer Age Statistical Inference ISBN: 1107149894 ISBN-13(EAN): 9781107149892 Издательство: Cambridge Academ Рейтинг: Цена: 9029.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The twenty-first century has seen a breathtaking expansion of statistical methodology, both in scope and in influence. 'Big data', 'data science', and 'machine learning' have become familiar terms in the news, as statistical methods are brought to bear upon the enormous data sets of modern science and commerce. How did we get here? And where are we going? This book takes us on an exhilarating journey through the revolution in data analysis following the introduction of electronic computation in the 1950s. Beginning with classical inferential theories - Bayesian, frequentist, Fisherian - individual chapters take up a series of influential topics: survival analysis, logistic regression, empirical Bayes, the jackknife and bootstrap, random forests, neural networks, Markov chain Monte Carlo, inference after model selection, and dozens more. The distinctly modern approach integrates methodology and algorithms with statistical inference. The book ends with speculation on the future direction of statistics and data science.
Автор: Whittlesea, Cate Название: Clinical Pharmacy and Therapeutics,IE. 6 ed. ISBN: 0702070114 ISBN-13(EAN): 9780702070112 Издательство: Elsevier Science Рейтинг: Цена: 5304.00 р. Наличие на складе: Поставка под заказ.
Описание:
'This new edition of Clinical Pharmacy and Therapeutics was really very helpful when I was doing an MSc course in Advancing Pharmacy Practice and it was really very helpful in all the clinical diseases I have to read for my PBL. I also used it as one of my most reliable reference books for the in-course simulation ward rounds and other clinical case studies. It is a great book to have as a practising clinical or hospital pharmacist or even community pharmacist.
It will also be of great use to anyone doing a course in pharmacotherapy. This book will always be of use to you throughout your studentship or when practising after graduation. It is also more portable than most other pharmacotherapy textbooks with the same amount of information.'
Now in its sixth edition, this best-selling, multi-disciplinary textbook continues to draw on the skills of pharmacists, clinicians and nurses to present optimal drug regimens.
The authors integrate an understanding of the disease processes with an appreciation of the pathophysiological processes, clinical pharmacy and the evidence base. Each chapter is co-written by a pharmacist and a clinician, and each chapter begins with key points and ends with cases to test understanding. The sixth edition is now on StudentConsult for the first time, giving online access to the full text.
Автор: Kahn Название: Pharmaceutical and Clinical Calculations, 2nd Edition ISBN: 1566768128 ISBN-13(EAN): 9781566768122 Издательство: Taylor&Francis Рейтинг: Цена: 27562.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Suitable for pharmacy students and practitioners, this title emphasizes contemporary pharmacy practices. It explains calculations involving various dosage forms such as oral liquids, solids, semi-solids, and topical medications. It includes coverage on discussion of prescription and medication orders and the calculations of suppositories.
Автор: Takashi Sozu; Tomoyuki Sugimoto; Toshimitsu Hamasa Название: Sample Size Determination in Clinical Trials with Multiple Endpoints ISBN: 3319220047 ISBN-13(EAN): 9783319220048 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1.Introduction.- 2.Continuous Co-primary Endpoints.- 3.Binary Co-primary Endpoints.- 4.Convenient Sample Size Formula.- 5.Continuous Primary Endpoints.- 6. Further Developments.- A.Sample Size Calculation Using other Contrasts for Binary Endpoints.- B.Empirical Power for Sample Size Calculation for Binary Co-primary Endpoints.- C.Numerical Tables for Ck in the Convenient Sample Size Formula for the Three Co-primary Continuous Endpoints Cace.- D.Software Programs for Sample Size Calculation for Continuous Co-primary Endpoints.- References.
Автор: Shuster Название: CRC Handbook of Sample Size Guidelines for Clinical Trials ISBN: 1138105392 ISBN-13(EAN): 9781138105393 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume helps medical researchers design clinical trials to improve survival, remission duration, or time to recurrence of disease. Written in a user-friendly step-by-step format, this work enables researchers, even those with no background in statistics, determine sample size and write statistical considerations for their protocols.
Описание: This volume helps medical researchers design clinical trials to improve survival, remission duration, or time to recurrence of disease. Written in a user-friendly step-by-step format, this work enables researchers, even those with no background in statistics, determine sample size and write statistical considerations for their protocols.
Accurate sample size calculation ensures that clinical studies have adequate power to detect clinically meaningful effects. This results in the efficient use of resources and avoids exposing a disproportionate number of patients to experimental treatments caused by an overpowered study.
Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies.
The book focuses on issues specific to the two types of correlated outcomes: longitudinal and clustered. For clustered studies, the authors provide sample size formulas that accommodate variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas to account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the level at which to perform randomization actually becomes a design parameter. The authors show how this can greatly impact trial administration, analysis, and sample size requirement.
Addressing the overarching theme of sample size determination for correlated outcomes, this book provides a useful resource for biostatisticians, clinical investigators, epidemiologists, and social scientists whose research involves trials with correlated outcomes. Each chapter is self-contained so readers can explore topics relevant to their research projects without having to refer to other chapters.
Описание: This book explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies. For clustered studies, the authors provide sample size formulas that account for variable cluster sizes and within-cluster correlation. For longitudinal studies, they present samp
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