Автор: Makio Mike Название: Laparoscopic Colorectal Cancer Surgery ISBN: 9811023190 ISBN-13(EAN): 9789811023194 Издательство: Springer Рейтинг: Цена: 12577.00 р. 13974.00-10% Наличие на складе: Есть (1 шт.) Описание: This unique guide describes colorectal surgery procedures using medical terminology and anatomical terms originating from embryology. In the last decade, laparoscopic procedures in gastrointestinal surgery have been enhanced and their safety has significantly improved. With the number of cases of colorectal cancer surgery increasing and laparoscopic surgery no longer considered a specialized surgery, the recognition of the correct anatomy is vital in these procedures. Unfortunately, however, the understanding of clinical anatomy is frequently separate from that of basic surgical concepts. Initially, the dissecting layer should be presumed to derive from the fascial anatomy based on embryological recognition. Furthermore, the techniques currently being used by surgeons should be described in sufficient detail and the appropriate anatomical terms should always be used. In view of this, this valuable monograph benefits gastrointestinal surgeons and general surgeons who are involved in the treatment of colorectal cancer.
Автор: Acc Название: Understand Colorectal Cancer Lamin Chart ISBN: 0781773342 ISBN-13(EAN): 9780781773348 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 3087.00 р. Наличие на складе: Поставка под заказ.
Описание: Defines colorectal cancer and shows colorectal anatomy with the following pathologies: Adenocarcinoma of colon; Circumferential carcinoma of the transverse colon; Colonic polyps Adenocarcinoma of jejunum; and, Adenocarcinoma of the rectosigmoid region.
Автор: Slaby Ondrej, Calin George A. Название: Non-Coding Rnas in Colorectal Cancer ISBN: 3319824910 ISBN-13(EAN): 9783319824918 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer. This work further provides the comprehensive overview and novel insights into using of non-coding RNAs as colorectal cancer biomarkers enabling early detection of the disease, prognostic stratification of the patients and prediction of therapeutic response. The reader is introduced to the overview of modern non-coding RNAs-based therapeutic strategies, and summary of their preclinical testing performed in colorectal cancer. The work is written for researchers who want to explore current state of the knowledge in this interesting field of molecular oncology.
Описание: Colorectal cancer is a major killer as the cases are increasing worldwide. The researches and studies in this field would be helpful to provide some efficient therapeutic measures for colorectal cancer. This book presents some basic steps being taken in o
Автор: Correia Название: Colorectal Cancer Liver Metastases ISBN: 3030254852 ISBN-13(EAN): 9783030254858 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Поставка под заказ.
Описание: Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.).
Описание: Colorectal cancer is one of the most common cancers found in many parts of the world. The challenges and mortality that this disease accompany, call for better and improved methods for patient care and treatment. This book presents the essential work that
Автор: Maurizio Ponz de Leon Название: Colorectal Cancer ISBN: 3642627625 ISBN-13(EAN): 9783642627620 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Colorectal cancer is one of the most frequent human tumors. This volume provides an updated and comprehensive description of the most relevant features of colorectal cancer - from molecular biology to prevention, from hereditary syndromes to new treatment modalities.
Автор: Peter Jordan Название: Targeted Therapy of Colorectal Cancer Subtypes ISBN: 3030027708 ISBN-13(EAN): 9783030027704 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Поставка под заказ.
Описание: Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide. Recent years have increased significantly our understanding of the genetic alterations that can underlie CRC, but also unraveled the molecular heterogeneity of the disease. Although a simple correlation between genetic pathways, histopathological features and clinical outcome cannot be established, the heterogeneity of CRC is also an opportunity for the development of targeted therapeutic approaches, able to treat an individual tumor with higher efficiency and less toxic side effects. One CRC subtype is characterized by high mutation rates (MSI-H), DNA methylation changes (CIMP-H), mutation in the BRAF oncogene and occurrence of serrated adenomas in the proximal colon. Other groups prevail in the distal colon and consist of either adenomatous polyps with chromosomal aberrations (CIN) and WNT pathway activation, or carry frequent KRAS mutation and metabolic deregulation, or have strong mesenchymal and infiltrative characteristics. Characterization of driver-mutation events in these CRC subgroups has led to the development of specific drugs targeting, for example, the MAPK pathway, but initial clinical trials have revealed unexpected response rates. The collection of chapters in this volume address the biology of specific CRC subtypes and how these may be targeted to improve precision therapy and clinical benefit for the patients.
Автор: Rodriguez-Bigas Название: Hereditary Colorectal Cancer ISBN: 1441966021 ISBN-13(EAN): 9781441966025 Издательство: Springer Рейтинг: Цена: 44582.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. This is the first book to cover Hereditary nonpolyposis colorectal cancer, also known as the Lynch syndrome, in one comprehensive text.
Автор: Giovanni Maria Romano Название: Multimodal Treatment of Recurrent Pelvic Colorectal Cancer ISBN: 8847057663 ISBN-13(EAN): 9788847057661 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book analyzes all aspects of modern multimodal treatment of locally recurrent rectal cancer in the pelvis in order to offer a panoramic overview of the different therapeutic options and enable the reader to balance their benefits and drawbacks. Indications for surgery and the surgical techniques themselves, including reconstruction techniques after major exenterative surgery, are clearly described and evaluated. The role of new imaging tools, such as MRI and PET-CT, in staging recurrences and guiding therapy is assessed and detailed consideration is given to the use of neoadjuvant and iterative radiotherapy and the indications for systemic chemotherapy. Morbidity, mortality, oncologic outcomes, and quality of life issues are carefully analyzed and options for pain control and palliation are examined. Finally, a national survey is presented on the state of the art in the surgical treatment of locally recurrent rectal cancer in Italy. While there has been a dramatic fall in the incidence of local pelvic recurrences, their treatment remains a major clinical challenge which requires a multidisciplinary approach and careful selection of the most appropriate strategy in each case. This book will aid practitioners in making the correct decisions in individual patients.
Автор: Helmut K. Seitz; B.C. Morson; Ulrich A. Simanowski Название: Colorectal Cancer ISBN: 3642859321 ISBN-13(EAN): 9783642859328 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The past 20 years have seen a surge of research into colorectal cancer, which is a reflection of the need to improve our methods of treating patients suffering from this increasingly common form of cancer.
Автор: John D. Potter; Noralane M. Lindor (Eds.) Название: Genetics of Colorectal Cancer ISBN: 0387095675 ISBN-13(EAN): 9780387095677 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Genetic susceptibility refers to how variations in a person`s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This book explores various findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology.
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