This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Thomas, Sabu Название: Molecular Imprinted Polymer Composites ISBN: 0128199520 ISBN-13(EAN): 9780128199527 Издательство: Elsevier Science Рейтинг: Цена: 34529.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Molecular Imprinted Polymer Composites: Synthesis, Characterisation and Applications covers the design of composite materials containing nanostructures and molecular imprinted polymers that has materialized the ever-sought out vision of homogeneous molecular imprinted polymers. The inherent high surface-to-volume ratio of nanostructures has served well in increasing the surface area of conventional bulk polymers. In recent decades, molecularly imprinted polymer nanocomposite materials have attracted much attention for their potential applications in the fields of separation science, sensing, drug delivery, waste water treatment and catalysis, hence this book provides a much needed update on progress.
Автор: Bo Mattiasson; Lei Ye Название: Molecularly Imprinted Polymers in Biotechnology ISBN: 3319207288 ISBN-13(EAN): 9783319207285 Издательство: Springer Рейтинг: Цена: 32652.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Controlled radical polymerization techniques for molecular imprinting.- From bulk polymers to nanoparticles.- Post-imprinting and in-cavity functionalization.- Characterization of MIPs (affinity, selectivity, site heterogeneity...).- Theoretical aspects and computer modelling.- MIPs in aqueous environments, by Bin Lu.- MIPs for binding macromolecules.- Solid phase extraction.- Sensors.- MIPs for catalysis and synthesis.- Wastewater treatment.- MIPs as tools for bioassays, biotransformation and drug delivery.
Описание: This book describes the various approaches for developing novel drug delivery systems and the criteria for selection of drugs and polymers for the development of nanotechnology and targeted drug delivery systems. It also covers concepts, events and biological processes involved in drug targeting, tumour targeting and brain specific delivery. The major focus is to describe innovative approaches, types, formulation techniques, technologies, applications and evaluation of certain novel drug delivery systems such as liposomes, nanoparticles, microcapsules or microspheres, monoclonal antibodies, niosomes, aquasomes, phytosomes, and electrosomes.
The book encapsulated the change through intense analysis, new technologies, innovative evaluation of carriers and an array of practical approaches for pulmonary drug and nucleic acid based therapeutic delivery system, which will be handy for budding scientist and professional as well. Innovative techniques for drug delivery systems, applications of old theories with distinct reevaluation and well explained diagrams are the major part of this book.
Описание: The second volume of the series on inorganic biochemistry and bio- physics is singularly devoted to magnetic resonance on systems of high molecular complexity. Recently, there have been important advances in magnetic resonance studies of polymers; these advances touch on all aspects of magnetic resonance, both theoretical and applied. Particular emphasis is placed here on multipulse experiments. We believe such an report will be of considerable interest to the readers of our series owing to the importance of magnetic resonance techniques in the investigation of biopolymers. Ivano Bertini Harry Gray Series Editors Preface This book is a record of the Proceedings of the International Symposium on "Advanced Magnetic Resonance Techniques in Systems of High Molecular Complexity", which was held in Siena between 15 and 18 May 1985. The idea of the meeting is due to Proff. N.M. Atherton, G. Giacometti and E. Tiezzi with the aim of honouring the scientific personality of Prof. S.I. Weissman. The meeting has been organized with the assistance of a National Committee formed by R. Basosi, I. Bertini, P. Bucci, C. Corvaia, A. Gamba, G. Martini, G.F. Pedulli, P.A. Temussi, and C.A. Veracini. The invited lecturers responded enthusiastically and a comprehensive picture of the theoretical and practical aspects of magnetic resonance could be therefore provided. The book contains all the plenary lectures delivered during the meeting and also a wide selection among the huge amount of contributions collected by the organizers.
Автор: Bo Mattiasson; Lei Ye Название: Molecularly Imprinted Polymers in Biotechnology ISBN: 3319371487 ISBN-13(EAN): 9783319371481 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Controlled radical polymerization techniques for molecular imprinting.- From bulk polymers to nanoparticles.- Post-imprinting and in-cavity functionalization.- Characterization of MIPs (affinity, selectivity, site heterogeneity...).- Theoretical aspects and computer modelling.- MIPs in aqueous environments, by Bin Lu.- MIPs for binding macromolecules.- Solid phase extraction.- Sensors.- MIPs for catalysis and synthesis.- Wastewater treatment.- MIPs as tools for bioassays, biotransformation and drug delivery.
Описание: A summary of the latest developments and applications of molecular imprinting for selective chemical sensing.
Автор: Songjun Li Название: Molecularly Imprinted Catalysts ISBN: 012801301X ISBN-13(EAN): 9780128013014 Издательство: Elsevier Science Рейтинг: Цена: 23244.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Molecularly Imprinted Catalysts: Principle, Synthesis, and Applications is the first book of its kind to provide an in-depth overview of molecularly imprinted catalysts and selective catalysis, including technical details, principles of selective catalysis, preparation processes, the catalytically active polymers themselves, and important progress made in this field. It serves as an important reference for scientists, students, and researchers who are working in the areas of molecular imprinting, catalysis, molecular recognition, materials science, biotechnology, and nanotechnology. Comprising a diverse group of experts from prestigious universities and industries across the world, the contributors to this book provide access to the latest knowledge and eye-catching achievements in the field, and an understanding of what progress has been made and to what extent it is being advanced in industry.
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