Preclinical Evaluation of Antimicrobial Nanodrugs, Bueno Juan
Автор: Bruno Oliveira de Veras Название: Antimicrobial Potential of Essential Oils ISBN: 1536169455 ISBN-13(EAN): 9781536169454 Издательство: Nova Science Рейтинг: Цена: 13462.00 р. Наличие на складе: Невозможна поставка.
Описание: Instead of relying on prescription medications with numerous dangerous side effects, what if you could opt for a safer, natural alternative to address your health concerns? Medicinal plants for therapeutic purposes have been used for many years. The antimicrobial activity of essential oils and their major constituents has been widely documented by several works, however, in a fragmented way. Based on this premise, this book is designed to provide an overview of current knowledge about the antimicrobial properties of essential oils and their mechanisms of action, either alone or in combination, as a possible tool for obtaining new antibiotics.
Автор: Anton Ficai, Alexandru Mihai Grumezescu Название: Nanostructures for antimicrobial therapy ISBN: 0323461522 ISBN-13(EAN): 9780323461528 Издательство: Elsevier Science Рейтинг: Цена: 26107.00 р. Наличие на складе: Поставка под заказ.
Описание:
Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms.
Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments.
Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues.
Автор: Jeffrey K. Aronson Название: Meyler`s Side Effects of Antimicrobial Drugs, ISBN: 0444532722 ISBN-13(EAN): 9780444532725 Издательство: Elsevier Science Рейтинг: Цена: 8420.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Suitable for internal medicine physicians and general practitioners who prescribe antibiotic drugs, like penicillin and tetracycline that cure bacterial infections, and antiviral drugs used to treat patients with HIV and herpes viruses.
Автор: Samanta, Indranil Название: Antimicrobial Resistance In Agriculture ISBN: 0128157704 ISBN-13(EAN): 9780128157701 Издательство: Elsevier Science Рейтинг: Цена: 16161.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Antimicrobial Resistance in Agriculture: Perspective, Policy and Mitigation is a valuable industrial resource that addresses complex, multi-factorial topics regarding farm, wild, companion animals, fish, and how the environment plays an important role in amplification and transmission of resistant bugs into the human food chain. Information of phenotypical and genotypical properties of each bacterial genus associated with antimicrobial resistance, transmission dynamics from different reservoirs (food animals, poultry, fishes) and control measures with alternative therapy, such as phytobiotics and nanomaterials are provided. Researchers, scientists and practitioners will find this an essential resource on the judicial use of antibiotics in animals and humans.
Автор: Bueno Juan Название: Preclinical Evaluation of Antimicrobial Nanodrugs ISBN: 3030438546 ISBN-13(EAN): 9783030438548 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The design and development of new standardized protocols for evaluating antimicrobial nanomedicines is needed for both the industry and clinical laboratory. These protocols must aim to evaluate laboratory activity and present models of pharmacokinetic-pharmacodynamic and toxicokinetic behavior that predict absorption and distribution. Likewise, these protocols must follow a theranostics approach, be able to detect promising formulations, diagnose the infectious disease, and determine the correct treatment to implement a personalized therapeutic behavior. Given the possibilities that nanotechnology offers, not updating to new screening platforms is inadequate as it prevents the correct application of discoveries, increasing the effect of the valley of death between innovations and their use. This book is structured to discuss the fundamentals taken into account for the design of robust, reproducible and automatable evaluation platforms. These vital platforms should enable the discovery of new medicines with which to face antimicrobial resistance (RAM), one of the great problems of our time.
Автор: by S Snigdha; Sabu Thomas; Название: Engineered Antimicrobial Surfaces ISBN: 9811546290 ISBN-13(EAN): 9789811546297 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume looks at the different aspects involved in controlling microbial growth and the techniques employed in obtaining sterile surfaces. It covers research on coatings, nano-materials, herbal materials, naturally occurring antimicrobials in designing antimicrobial surfaces. It discusses issues of antibiotic resistance, synthesis techniques, toxicity, and current and potential applications of antimicrobial surfaces, and this book will serve as a useful reference to a broad range of scientists, industrial practitioners, graduate and undergraduate students, and other professionals in the fields of polymer science and engineering, materials science, surface science, bioengineering and chemical engineering.
Автор: Molly Courtenay Название: Antimicrobial stewardship for nursing practice / ISBN: 178924269X ISBN-13(EAN): 9781789242690 Издательство: Marston Book Services Рейтинг: Цена: 4425.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With antimicrobial resistance on the rise, appropriate stewardship is more important than ever. This textbook, the first written by nurses for nurses, provides a clear and concise approach to good practice.
Описание: The increasing prevalence of antibiotic-resistant bacteria, known as superbugs, has threatened the field of infectious disease medicine over most of the past century. Antimicrobial peptides, a crucial part of innate immunity that exists in most living organisms, have become a central pillar for the next generation of medical challenges for infectious diseases, cancer, and other health problems. The development of new antimicrobial peptides to tackle ongoing superbug infections, cancer and other diseases is a fast-growing research area for chemistry, medical physics, biological science, food and agricultural science and different disciplines of medicine. This volume discusses the basic science behind potential pharmacological agents, which is necessary to understand how these peptides can be used in our daily lives. The book provides a foundation for a wide variety of antimicrobial peptide-based therapeutic approaches, which is invaluable for established scientists, junior researchers, and students involved in basic science, material science, the medical field and different disciplines of engineering. It contains nine chapters written by world leaders in this area, covering basic science and possible therapeutic applications with immense societal implications. Antimicrobial peptides are an exciting new therapeutic agent with promising applications for a wide variety of illnesses.
Автор: Fong Название: Antimicrobial Resistance in the 21st Century ISBN: 3319785370 ISBN-13(EAN): 9783319785370 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Antimicrobial resistance is now a general problem. Many of us have elderly relatives who died from a drug-resistant infection, and some of us have suffered from a resistant urinary infection that likely came from intestinal bacteria following antibiotic consumption. Antimicrobial Resistance in the 21st Century provides a broad introduction to the subject in which the situation with problematic pathogens is detailed, the biology of resistance is described, and gaining approval for new antibiotics is discussed. Some topics are immediately practical, such as watching for resistant pathogen sub-populations in cultures taken from patients; other topics point to future research efforts that may lead to new antimicrobials and ways to stimulate the action of existing ones. Overall, Antimicrobial Resistance in the 21st Century provides an update for physicians, serves as a starting point for graduate students interested in solving the resistance problem, and may serve as a text for a course on resistance. Lay readers familiar with microbiology will gain an appreciation for a medical issue that promises to be one of the most important of our time. Ignatius Fong, Department of Medicine, University of Toronto Series Editor – Emerging Infectious Diseases of the 21st Century David Shlaes, Founder, Anti-Infectives Consulting Editor – Antimicrobial Agents and ChemotherapyKarl Drlica, The Public Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey
Описание: The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Antimicrobial Drug Interactions,” delivers a quick clinical resource that distills relevant drug interactions by antimicrobial drug class. The book provides informative tables on specific drug-drug interactions that include the degree and severity of the expected interaction. A mechanistic basis for drug-drug interactions is also provided to link observed interactions to pharmacologic characteristics of key drug classes. This complete resource is organized by major antibacterial, antimycobacterial, antiviral, antifungal, antimalarial, and antiprotozoal class. In line with current innovations in antimicrobial drug development, a distinct chapter on the pharmacologic management of drug interactions in hepatitis B virus (HBV) and hepatitis C virus (HCV)-related infections is included. Two new chapters are dedicated to the management of human immunodeficiency virus (HIV) drug-drug interactions given the breadth of antiretroviral class-specific effects. This comprehensive review of known drug interactions and strategies to manage them is an invaluable resource to all health care practitioners.
Автор: Tom?s G. Villa; Patricia Veiga-Crespo Название: Antimicrobial Compounds ISBN: 3662512165 ISBN-13(EAN): 9783662512166 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. It combines basic research with clinical applications.
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