Автор: Godfrey Grech; Iris Grossman Название: Preventive and Predictive Genetics: Towards Personalised Medicine ISBN: 3319153439 ISBN-13(EAN): 9783319153438 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Pharmacogenomics supports personalized medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large. Current routine practice for diagnosing and treating patients is conducted by correlating parameters such as age, gender and weight with risks and expected treatment outcomes. In the new era of personalized medicine the healthcare provider is equipped with improved ability to prevent, diagnose, treat and predict outcomes on the basis of complex information sources, including genetic and genomic data. Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.
Автор: Godfrey Grech; Iris Grossman Название: Preventive and Predictive Genetics: Towards Personalised Medicine ISBN: 3319380575 ISBN-13(EAN): 9783319380575 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.
Описание: This book is intended for periodontal residents and practicing periodontists who wish to incorporate the principles of moderate sedation into daily practice. Comprehensive airway management and rescue skills are then documented in detail so that the patient may be properly managed in the event that the sedation progresses beyond the intended level.
Описание: An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities;
Название: Personalised health care ISBN: 3030523985 ISBN-13(EAN): 9783030523985 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction (Boccia) 1. Chapter 1: Identification of biomarkers for the prevention of chronic disease (Editors: Adany, Boccia). 1.1 Van Duijn (Identification of biomarkers for primary and secondary prevention - Liu)1.2 Boccia (Identification of biomarkers for tertiary prevention - Mariani, Giraldi, Pastorino)1.3 Adany (Application of Single-Nucleotide Polymorphism-Related Risk Estimates in Identification of Increased Genetic Susceptibility to Specific Diseases)1.4 Giordano Bottа - Allelica (Non Academic Vision) Recommendation 1 Personalised interventions for the prevention of chronic diseases require robust evidence of efficacy and/or effectiveness of the new technology when implemented in health care. 2. Chapter 2: Evaluation of predictive genomic applications (Editor: Villari) 2.1 The economic evaluation of genetic/genomic applications (D'Andrea)2.2 The HTA approach for the evaluation of genetic/genomic applications (Pitini)2.3 Training needs in genomics of Public Health Professionals (Rosso) Recommendation 2A comprehensive evaluation of the value (outcomes/cost) of the new technology should also include evidence on the social aspects, and context-related dimensions to better support the clinical decision-making process. Genetic or genomic applications with evidence of efficacy, effectiveness, and cost-effectiveness should be implemented in clinical and public health practice. 3. Chapter 3: Ethico-legal and policy issues surrounding personalised medicine (Editor: Sandor) 3.1 Zawati (Ethical issue) 3.2 Calabro, Hoxaij, Boccia (Policy issue, with a focus on training in genomics for healthcare professionals)3.3 Calabro, Sassano, Boccia (Policy issue, with a focus on citizens and DTC)3.4 Sandor (Legal issue) Recommendation 3The era of genomics requires that we clarify and validate the obligations and responsibilities of the research community, research participants, and the general public including patients through collaboration and dissemination of high-quality ethical, policy, and legal analysis. 4. Chapter 4: Roles and responsibilities of stakeholders in informing healthy individuals on their genome: a sociotechnical analysis (Editor: Cornel) (Martina Cornel, Tessel Rigter, and Carla van El)4.1 Responsible translation of new genomic technologies in the context of screening of healthy adults4.2 Examples from hereditary cardiovascular diseases and hereditary cancers Recommendation 4 A dedicated effort is necessary to stimulate further implementation of evidence-based interventions in health care, such as testing of family members in cases of hereditary cancers or cardiovascular diseases. 5. Chapter 5: Identification of organizational models for the provision of predictive genomic applications (Editor: De Vito) 5.1 De Vito/Unim (Delivery models for genetic/genomic applications)5.2 Cornel (Barriers and Facilitating Factors for Implementation of Genetic Services)5.3 Gray/Jani (Design systems that integrate genomic information to deliver personalised care)5.4 Roldan (Clinical decision support tool to assist physicians in the screening of genetic diseases) Recommendation 5 The integration of genomic sciences in other medical spec
Описание: Bringing the experiences of patients, carers and practitioners to the fore, this book explores how individual and collective futures are crafted through their work and care. The authors chart the different kinds of care and work involved in efforts to personalise cancer medicine, as well as the ways in which benefits and opportunities are unevenly realised and distributed. -- .
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