Fibrous Proteins: Structures and Mechanisms, David A.D. Parry; John M. Squire
Автор: Tzi Bun Ng, Jack Wong, Ryan Tse, Tak Fu Tse, Helen Chan Название: Hemagglutinins: Structures, Functions and Mechanisms ISBN: 1536157082 ISBN-13(EAN): 9781536157086 Издательство: Nova Science Рейтинг: Цена: 32312.00 р. Наличие на складе: Невозможна поставка.
Описание: Hemagglutinins refers to glycoproteins which bring about agglutination of erythrocytes or hemagglutination. Hemagglutination can be used to identify surface antigens on erythrocytes (with known antibodies) and, hence, the blood type of an individual. Hemagglutinins consist of lectins and antibodies. Lectins (from the Latin legere, "to select") are non-immune glycoproteins that exhibit reversible binding to specific carbohydrate structures, glycans of glycoproteins, glycolipids and polysaccharides. Lectins own at least one non-catalytic domain, and, in some cases, a few carbohydrate binding domains, which enable them to effect agglutination of erythrocytes and other cells or precipitation of glycoconjugates. Lectins are found in a constellation of organisms and display an array of activities. Topics discussed in this book encompass algal lectins, plant type 2 ribosome inactivating proteins, edible legume lectins, jacalin, jacalin-related lectin, wheat lectins, rice lectins, banana lectins and potato lectin, immunomodulatory action of plant lectins, piezoelectric assay using the galactose-binding Bauhinia monandra leaf lectin and its antibody as a potent tool for detection of antigen-antibody recognition, assays using hemagglutinins of different origins to investigate their mechanisms of action, lectins from medicinal herbs and medicinal mushrooms, C-type lectins from a diversity of invertebrates and vertebrates, fish lectins and amphibian lectins.
Автор: Alfred Wittinghofer Название: Ras Superfamily Small G Proteins: Biology and Mechanisms 2 ISBN: 3319378082 ISBN-13(EAN): 9783319378084 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.
Описание: This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased infectious prions (PrPSc), using MD and MM techniques. As we all know, prion diseases, caused by the body's own proteins, are invariably fatal and highly infectious neurodegenerative diseases effecting humans and almost all animals for a major public health concern. Prion contains no nucleic acids and it is a misshapen or conformation-changed protein that acts like an infectious agent; thus prion diseases are called “protein structural conformational” diseases. PrPC is predominant in ?-helices but PrPSc are rich in ?-sheets in the form as amyloid fibrils; so very amenable to be studied by MD techniques. Through MD, studies on the protein structures and the structural conversion are very important for revealing secrets of prion diseases and for structure-based drug design or discovery. Rabbits, dogs, horses and buffaloes are reported to be the few low susceptibility species to prion diseases; this book's MD studies on these species are clearly helpful to understand the mechanism underlying the resistance to prion diseases. PrP(1-120) usually has no clear molecular structures; this book also studies this unstructured region through MD and especially MM techniques from the global optimization point of view. This book is ideal for practitioners in computing of biophysics, biochemistry, biomedicine, bioinformatics, cheminformatics, materials science and engineering, applied mathematics and theoretical physics, information technology, operations research, biostatistics, etc. As an accessible introduction to these fields, this book is also ideal as a teaching material for students.
Автор: Alfred Wittinghofer Название: Ras Superfamily Small G Proteins: Biology and Mechanisms 1 ISBN: 3709118050 ISBN-13(EAN): 9783709118054 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes regulated by specific members of this family. The focus of this first volume is on the Rho and Ras subfamily of small G proteins. Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease. Together with Volume 2, this book provides a comprehensive and state-of-the-art work on small G-proteins (GTPases). It is intended for graduates and professors in biochemistry and cell biology already working on small G-proteins (small GTPases), but also offers an extremely valuable resource for those readers who are new to the field.
Автор: Alfred Wittinghofer Название: Ras Superfamily Small G Proteins: Biology and Mechanisms 1 ISBN: 370911988X ISBN-13(EAN): 9783709119884 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The focus of this first volume is on the Rho and Ras subfamily of small G proteins.Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease.
Автор: Nakasako Masayoshi Название: Hydration Structures of Proteins: Atomic Details ISBN: 4431569170 ISBN-13(EAN): 9784431569176 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Topics on protein hydration from the past 25 years are examined, most of which involve crystallography, fluorescence measurements, and molecular dynamics simulations.In X-ray crystallography and molecular dynamics simulations, recent advances have accelerated the study of hydration structures over the entire surface of proteins.
Автор: Alfred Wittinghofer Название: Ras Superfamily Small G Proteins: Biology and Mechanisms 2 ISBN: 3319077600 ISBN-13(EAN): 9783319077604 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily members. As in Volume 1, the book is written by international renowned scientists in the field of small G-proteins. In elaborate reviews, biochemistry, structure, function and G-protein - effector interactions are described. Together with Volume 1 this book provides an comprehensive state-of-the-art work on small G-proteins (GTPases). It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.
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