Non-coding RNAs in the Vasculature, Thomas Thum; Stefanie Dimmeler
Автор: Amy Firth; Jason X.-J. Yuan Название: Lung Stem Cells in the Epithelium and Vasculature ISBN: 3319162314 ISBN-13(EAN): 9783319162317 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers the identification and role of endogenous lung stem cells in health and disease, particularly the most recent advances. In addition, it discusses the rapidly growing field of stem cells and cell therapy as it relates to lung biology and disease as well as ex vivo lung bioengineering. Such approaches may provide novel therapeutic approaches for lung diseases. Human pluripotent stem cell differentiation to model the pulmonary epithelium and vasculature is also discussed. World-recognized scientists who specialize in studying both the lung epithelium and pulmonary vasculature contribute the chapters. Topics covered include: stem cell niches in the lung, the role of progenitor cells in fibrosis and asthma, iPSC in modeling lung disease, vascular repair by endothelial progenitor cells and circulating fibrocytes in pulmonary vascular remodeling. This volume of the Stem Cell Biology and Regenerative Medicine series is essential reading for researchers and clinicians interested in stem cells, lung biology and regenerative medicine. It is also an invaluable resource for advanced students studying cell biology, regenerative medicine and lung physiology.
Автор: Yong-Xiao Wang Название: Pulmonary Vasculature Redox Signaling in Health and Disease ISBN: 3319632442 ISBN-13(EAN): 9783319632445 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The main goal of this book is to form a high-quality platform in which well-known and emerging pioneering basic, translational and clinical scientists can present their latest, exciting findings in the studies of redox signaling in the pulmonary vasculature.
Описание: The main goal of this book is to form a high-quality platform in which well-known and emerging pioneering basic, translational and clinical scientists can present their latest, exciting findings in the studies of redox signaling in the pulmonary vasculature.
Автор: Morris Kevin V. Название: Long Non-Coding Rnas in Human Disease ISBN: 3319795511 ISBN-13(EAN): 9783319795515 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.
Автор: ?ur?ica Ugarkovi? Название: Long Non-Coding RNAs ISBN: 364226655X ISBN-13(EAN): 9783642266553 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Long Non-Coding RNAs provides an overview of the rapidly advancing field, and describes the epigenetic and non-epigenetic mechanisms by which they regulate various biological functions in model systems. Readers will find a discussion of the role of ncRNAs in sex chromosome dosage compensation, and more.
Автор: Song Erwei Название: The Long and Short Non-Coding Rnas in Cancer Biology ISBN: 9811093679 ISBN-13(EAN): 9789811093678 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Non-coding RNAs: New Players in Cancers.- The Working Modules of Long Non-coding RNAs in Cancer Cells.- Methods to Study Long Non-coding RNA Biology in Cancer.- Relationship between Non-coding RNA Dysregulation and Epigenetic Mechanisms in Cancer.- Non-coding RNAs in Growth and Death of Cancer Cells.- Non-coding RNAs in Cancer Cell Plasticity.- Non-coding RNAs in Regulation of Cancer Metabolic Reprogramming.- Non-coding RNAs in Tumor Angiogenesis.- Non-coding RNAs in Cancer Immunity.- Non-coding RNAs in Therapeutic Resistance of Cancer.- Non-coding RNAs Regulating Cancer Signaling Network.- Non-coding RNAs Regulating NFkB Signaling.- Non-coding RNAs Regulating p53 and c-Myc Signaling.- Viral Non-coding RNAs in Cancer Biology.- Non-coding RNAs in Cancer Diagnosis.- Therapeutic Potentials of Non-coding RNAs: Targeted Delivery of NcRNAs in Cancer Cells.
Автор: Volker A. Erdmann; Jan Barciszewski Название: Non Coding RNAs in Plants ISBN: 3642269990 ISBN-13(EAN): 9783642269998 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Discovered just 20 years ago, ncRNAs have been dubbed the `secret regulators` of cells. Only recently has their function in plants been investigated. In this book leading researchers relate recent discoveries about the role played by small ncRNA in plants.
Автор: Robert J. Tomanek Название: Coronary Vasculature ISBN: 148997380X ISBN-13(EAN): 9781489973801 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Ischemic heart disease is the leading cause of morbidity and mortality in the developed world. The high metabolism and oxygen demand of the cardiac myocardium depends on both a high blood flow and a rich capillary density. For this reason, the growth of the coronary vasculature is vital, not only in early development, but also in the adult faced with various stresses. Novel technologies have enabled the discovery of the molecular mechanisms underlying the growth and assembly coronary vessels, and this volume covers the hierarchy of the coronary vasculature from its embryonic origins through its postnatal growth, adulthood, and senescence. Chapters address normal coronary development, coronary anomalies and their possible underlying developmental errors, coronary vessel adaptations to exercise training, aging, hypoxia, myocardial ischemia, and cardiac hypertrophy. This comprehensive overview of current research in coronary vessels and myocardial perfusion was written by Dr. Robert J. Tomanek, Emeritus Professor of Anatomy and Cell Biology at the University of Iowa. The book reviews, discusses, and integrates findings from various areas of coronary vasculature research, and as a result, will be a valuable reference source for cardiovascular scientists and physicians for many years to come.
Автор: Ahmad M. Khalil Название: Molecular Biology of Long Non-coding RNAs ISBN: 3030170853 ISBN-13(EAN): 9783030170851 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Advances in the field also include better characterization of human long non-coding RNAs, novel insights into their roles in human development and disease, their diverse mechanisms of action and novel technologies to study them.
Автор: Yi Feng; Lin Zhang Название: Long Non-Coding RNAs ISBN: 1493933760 ISBN-13(EAN): 9781493933761 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume assembles a broad spectrum of methods used in long non-coding RNAs (lncRNA) research, ranging from computational annotation of lncRNA genes to molecular and cellular analyses of the function of individual lncRNA.
Автор: Yi Feng; Lin Zhang Название: Long Non-Coding RNAs ISBN: 1493980351 ISBN-13(EAN): 9781493980352 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume assembles a broad spectrum of methods used in long non-coding RNAs (lncRNA) research, ranging from computational annotation of lncRNA genes to molecular and cellular analyses of the function of individual lncRNA.
Автор: Slaby Ondrej, Calin George A. Название: Non-Coding Rnas in Colorectal Cancer ISBN: 3319824910 ISBN-13(EAN): 9783319824918 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer. This work further provides the comprehensive overview and novel insights into using of non-coding RNAs as colorectal cancer biomarkers enabling early detection of the disease, prognostic stratification of the patients and prediction of therapeutic response. The reader is introduced to the overview of modern non-coding RNAs-based therapeutic strategies, and summary of their preclinical testing performed in colorectal cancer. The work is written for researchers who want to explore current state of the knowledge in this interesting field of molecular oncology.
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